Amanita muscaria mushrooms, known for their hallucinogenic effects, have grown in popularity and availability. However, use can cause delirium, coma, and death. Moreover, the US Food and Drug Administration (FDA) has stated that Amanita muscaria, its extracts, and certain constituents (muscimol, ibotenic acid, and muscarine) are unapproved additives that do not meet the Generally Recognized as...
Objective: Amanita muscaria mushrooms, known for their hallucinogenic effects, have grown in popularity and availability. However, use can cause delirium, coma, and death. Moreover, the US Food and Drug Administration (FDA) has stated that Amanita muscaria, its extracts, and certain constituents (muscimol, ibotenic acid, and muscarine) are unapproved additives that do not meet the Generally...
= 26.38, ~50% past-month cannabis use by design) completed an online survey. Multivariable regression assessed sociodemographics, mental health, and adverse childhood events (ACEs) in relation to: (1) past-year psychedelic use; and (2) among those reporting lifetime use: (a) lifetime microdosing and (b) use motives. Lifetime and past-year psychedelic use were 27.7% and 11.9% (commonly...
Retail sales of intoxicants, including derived intoxicating cannabis products (DICPs) such as delta-8 tetrahydrocannabinol (THC) and hallucinogenic mushrooms, have rapidly increased throughout the US, despite their sale being federally illegal. This study assessed DICP and hallucinogenic mushroom availability in US smoke shops with differing DICP and psilocybin laws. In May-October 2025, using...
This study assessed the correlates of cannabis and psychedelic use and legalization support among young adults in the United States (US). Using 2025 data among adults ages 18–34 (n = 3227), we assessed cannabis and psychedelic message exposure and perceptions, mental health symptoms (Patient Health Questionnaire-4 [PHQ-4]), and adverse childhood experiences (ACEs) in relation to past-6-month...
Following the United States (U.S.) Federal Agriculture Improvement Act of 2018, many retailers began selling intoxicating cannabis products, including Delta-8 tetrahydrocannabinol (THC) as "hemp," claiming that it provided a legal loophole to do so. This qualitative study assessed Delta-8 THC messaging on YouTube, the world's second-most visited website. In 2022, two researchers searched the...
Delta-8 tetrahydrocannabinol (THC) is a psychoactive substance from the Cannabis plant that has been rising in popularity in the United States since the 2018 US Farm Bill implicitly legalized it. This study reviewed research from peer-reviewed and non-peer-reviewed (e.g. anecdotal and news) reports related to delta-8 THC to summarize current knowledge and implications for public health and...
The 2018 U.S. Federal Agriculture Improvement Act ("Farm Bill") resulted in what some have called a "legal loophole" in cannabis regulation. As different types of cannabis products proliferate, so has the terminology used to attempt to categorize them. This article presents a variety of potential descriptors to encourage dialogue about the language used to classify the multitude of psychoactive...