International journal of cardiology
February 2004
Paula Raviña, Jose Maria Quiroga, Tomas Raviña
3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') is an amphetamine synthetic analog widely used as an recreational drug. Acute and severe toxic effects following MDMA ingestion include hyperthermia, arrhythmias, rhabdomyolisis, disseminated intravascular coagulation, hepatotoxicity and even death. Recently, we treated a patient in whom hyperkalemia, in the absence of renal failure,...
Psychological Medicine
January 28, 2004
Karen L. Hanson, Mónica Luciana
71 citations
Background. Use of MDMA (ecstasy), a serotonin neurotoxin, has been associated with memory impairment and psychological dysfunction. This study examined cognitive functioning in abstinent MDMA users and MDMA-naïve controls. Method. Participants completed measures of intelligence, motor function, attention, memory span, verbal fluency, immediate and delayed verbal memory, and working memory....
Life Sciences
January 2, 2004
Rabi Simantov
3,4-Methylenedioxymethamphetamine (MDMA), commonly referred to as Ecstasy, is a widely abused, psychoactive recreational drug, which induces short- and long-term neuropsychiatric behaviors. This drug is neurotoxic to serotonergic neurons in vivo, and induces programmed cell death in cultured human serotonergic cells and rat neocortical neurons. Over the years it has been shown that MDMA alters...
Dancecult
2004
Daniel Paul Schnee
An absolute insider of the international underground electronic music scene for 20 years or so, Riccardo Balli is the best conceivable Charon for those who weren't there and want to get at least a flavour of what it was-and still is-all about. But beware, Balli is neither a music critic nor a music historian. Rather, a DJ, label owner, composer, novelist, live performer and, above all, a...
Neuropsychobiology
2004
A. C. Parrott
152 citations
MDMA (3,4-methylenedioxymethamphetamine) or ‘ecstasy’ is a ring-substituted amphetamine derivative, which is widely used as a recreational drug, most particularly at dances and raves. Around 80–95% of dancers/ravers report using ecstasy/MDMA, compared to 5–15% of young people in general. This paper will consider the possible contribution of stimulatory environmental conditions to the...
Adicciones
December 15, 2003
Una D. Mccann, George A. Ricaurte
El incremento del consumo de éxtasis (MDMA) por parte de los jóvenes ha obligado al estudio de efectos a corto y medio plazo sobre el SNC. En la última década, se demostró la existencia de neurotoxicidad serotoninérgica en el SNC. Recientemente aparecieron estudios tendentes a demostrar también daño dopaminérgico que se ha evidenciado en experimentación animal. Las diferentes técnicas de...
Adicciones
December 15, 2003
Pedro Lorenzo Fernández, Ignacio Lizasoain Hernández
En este capítulo hacemos una revisión de las características farmacológicas de las principales drogas recreativas englobadas en 2 grupos: drogas de diseño y alucinógenos. Las drogas de diseño (término acuñado por G Henderson) comprenden: el grupo de los derivados de las feniletilaminas (derivados de anfetaminas) como el MDMA (éxtasis), el grupo de los opiáceos sean derivados del fentanilo o de...
Adicciones
December 15, 2003
Pilar A. Sáiz Martínez, Paz García-Portilla González, Begoña Paredes Ojanguren et al.
3 citations
La MDMA (éxtasis), es sin duda, la droga que mayor popularidad ha alcanzado durante la última década. A pesar de haber sido sintetizada en 1912, no es hasta finales de los años 70 cuando comienza a ser utilizada por diversos grupos poblacionales en Estados Unidos (estudiantes, yuppies, gays y new agers). En el año 1985 es incluida en la Lista I de la Comprehensive Substances Act americana y en...
Addiction Biology
December 1, 2003
Nahal Ketabi‐Kiyanvash, Johanna Weiss, Walter Emil Haefeli et al.
Abstract: There are increasing numbers of deaths related to taking MDMA, MDE and PMA reported where the deceased typically took several different drugs with these compounds. Hence, mutual modulation of the pharmacokinetics in drug combinations with “ecstasy” might be a risk factor for “ecstasy”‐related morbidity. Regarding potential drug‐drug interactions, there are no data evaluating a...
Journal of Psychopharmacology
December 1, 2003
C. T. J. Lamers, Johannes G. Ramaekers, N. D. Muntjewerff et al.
105 citations
Ecstasy (3,4-methylenedioxymethamphetamine, MDMA) is a psychoactive recreational drug widely used by young people visiting dance parties, and has been associated with poor cognitive function. The current study assessed the influence of a single dose of MDMA 75 mg and alcohol 0.5 g/kg on cognition, psychomotor performance and driving-related task performance. Twelve healthy recreational ecstasy...