The MIT Press eBooks
November 21, 2023
Ross Crockford
1 citation
Hausner originally doubted that she could be helped.But as he listened to a recording of Hana's third LSD session, he saw some hope."The most pronounced aspect of this session is her archetypal regression into the realm of antiquity and to the very beginnings of humanity," Hausner later wrote. 1 "Hana is beginning to formulate a new attitude toward death and eternity."Over the next six months,...
The MIT Press eBooks
November 21, 2023
Stephen Snelders
1 citation
Dutch psychedelic history had its own characteristics. In psychiatry, LSD therapy was used for the management of the traumas of World War II; in Dutch society, overlapping groups of activists and psychedelics users were involved in a playful transformation of society into a “Magical Center”; and in economics, the Netherlands became a key player in the illegal production and distribution of LSD...
The MIT Press eBooks
November 21, 2023
Magaly Tornay
From its very beginning, when a drop of LSD-25 permeated the skin of Albert Hofmann’s fingertips in Sandoz laboratories in 1943, the substance has been a negotiator of boundaries. Symbolized by Hofmann’s bicycle ride, the first intentional trip with the mysterious drug, it has since stood for journeys into unknown realms, expanding limits, and subverting authority. In its early history,...
European Psychiatry
November 17, 2023
L. Silva, L. Bravo
1 citation
Introduction Lysergic acid diethylamide (LSD) a semi synthetic hallucinogen, was first synthetized by Albert Hofmann in 1938 and its psychological properties were not discovered until 1943. There was a brief renaissance of its use in psychiatry, specifically in assisted psychotherapy for the treatment of alcoholism, neurosis and psychosomatic disorders. However, research with LSD and others...
South African Medical Journal
November 6, 2023
J Van Der Walt, R Parker
3 citations
Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic pain often fails to meet the needs of these patients. Novel ways of treating people who suffer from chronic nociplastic pain with classic psychedelic agents may offer a new lens...
Journal of Psychopharmacology
October 31, 2023
Kurt Stocker, Matthias Hartmann, Laura Ley et al.
22 citations
Background: Research with the Psychedelic Experience Questionnaire/Scale (PES) focuses on questions relating to mystical experience (Mystical Experience Questionnaire (MEQ)). The psychometric potential of the non-MEQ items of the PES remains largely unexplored. Aims: We investigated whether the PES also yields subscales besides the MEQ30 subscales. Methods: Data from 239 PES measurements (140...
Cultura y Droga
October 19, 2023
Verónica María Peña Garcia
Este artículo busca dar a conocer las experiencias y los enfoques de trabajo que tienen los facilitadores de estados expandidos de consciencia que acompañan procesos con LSD. Reconociendo que el acompañamiento de este tipo de experiencias es una práctica que viene en aumento y que reduce los riesgos inherentes a las mismas, surgió el deseo de ahondar sobre éstas, brindando una perspectiva desde...
Research Directions Depression
October 13, 2023
Ian B. Hickie, F. Markus Leweke, Allan H. Young
1 citation
In recent years, there has been considerable enthusiasm among research groups focused on developing novel therapies for treatment-resistant depression, and a wider community that has had experiences using recreational drugs, in more systematic evaluation of the therapeutic value of these compounds (Goodwin et al., 2022; Young, 2023). This has also been associated with advocacy for...
The Journal of Organic Chemistry
October 6, 2023
Jeremy R Tuck, Lee E. Dunlap, David E. Olson
7 citations
Lysergic acid diethylamide (LSD), a semisynthetic ergoline alkaloid analogue and hallucinogen, is a potent psychoplastogen with promising therapeutic potential. While a variety of synthetic strategies for accessing ergoline alkaloids have emerged, the complexity of the tetracyclic ring system results in distinct challenges in preparing analogues with novel substitution patterns. Methods of...
Pilot and Feasibility Studies
October 5, 2023
Carina Joy Donegan, Dimitri Daldegan-Bueno, Rachael Sumner et al.
23 citations
Globally, an estimated 260 million people suffer from depression [1], and there is a clear need for the development of new, alternative antidepressant therapies. In light of problems with the tolerability and efficacy of available treatments [2], a global trend is emerging for patients to self-treat depression with microdoses of psychedelic drugs such as lysergic acid diethylamide (LSD) and...