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LSD: all studies

Page 189 of 282: studies 1,881 to 1,890 of 2,815, newest first. Back to the LSD overview

Research

Measuring Insight Level After Psychedelic Experience Among The Indian Population

April 27, 2024 Chandana P Vibin, Jahangir Majeed

This study explores the relationship between psychedelic use and insight among Indian adults aged 18 to 40 years. Psychedelics, such as LSD and psilocybin, are known for altering consciousness and potentially enhancing self-awareness. A total of 100 participants (79 males and 21 females) completed the Psychedelic Integration Scale (PIS), which includes the Integration Engagement Scale (IES) and...

Discovery and Structure–Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists

Journal of Medicinal Chemistry April 22, 2024 Karla Frydenvang, Emil Märcher-Rørsted, Anders A. Jensen et al. 7 citations

Classical psychedelics such as psilocybin, lysergic acid diethylamide (LSD), and N,N-dimethyltryptamine (DMT) are showing promising results in clinical trials for a range of psychiatric indications, including depression, anxiety, and substance abuse disorder. These compounds are characterized by broad pharmacological activity profiles, and while the acute mind-altering effects can be ascribed...

DOI: 10.1021/acs.jmedchem.4c00082 (opens in new tab) Pharmacology 5-HT Receptor Structure–activity relationship Serotonin agonist +1

The selective 5-HT2A receptor agonist LPH-5 induces persistent and robust antidepressant-like effects in rodents

bioRxiv Preprint Server April 19, 2024 Anders A. Jensen, Cláudia R. Cecchi, Meghan Hibicke et al. preprint

Psychedelic-assisted psychotherapy has over the last decade emerged as a promising treatment strategy for mental health disease, and the therapeutic potential in classical psychedelics such as psilocybin, LSD and 5-MeO-DMT is presently being pursued in a plethora of clinical trials. However, the resurgent interest in the drugs as therapeutics has also prompted a search for novel agents with...

Trips Through the Skin: Reviewing Cutaneous Drug Reactions to Psychedelics and Hallucinogens

Dermatitis April 18, 2024 Syed Minhaj Rahman, Yousef Salem, Aamir Hussain 4 citations

Although psychedelic and hallucinogenic substances have gained popularity for therapeutic use, their dermatologic adverse effects are poorly characterized. This review characterizes the cutaneous reactions associated with psychedelic and hallucinogenic drugs. A review of PubMed and Scopus was conducted from the inception of databases to August 31, 2023. Search terms included drug names and...

DOI: 10.1089/derm.2023.0292 (opens in new tab) Psilocybin Hallucinogen Trips architecture Dermatology

A dual-receptor model of serotonergic psychedelics

bioRxiv (Cold Spring Harbor Laboratory) April 15, 2024 Arthur Juliani, Veronica Chelu, Laura Graesser et al. 4 citations preprint

Abstract Serotonergic psychedelics have been identified as promising next-generation therapeutic agents in the treatment of mood and anxiety disorders. While their efficacy has been increasingly validated, the mechanism by which they exert a therapeutic effect is still debated. A popular theoretical account is that excessive 5-HT2a agonism disrupts cortical dynamics, relaxing the precision of...

MDMA (3,4-methylenedioxy-methamphetamine)

Drug Addiction Mechanisms in the Brain April 8, 2024 Jayalakshmi Krishnan 1 citation

3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug very similar to hallucinogens and stimulants. This drug is also called ecstasy or molly. It produces feelings of pleasure, warmth, distorted sensory time and perception. MDMA increases the activity of serotonin, dopamine and norepinephrine in the brain. It causes various health effects such as nausea, sweating, chills, muscle...

Are first responders interested in psychedelics? Assessing previous use, interest, and willingness to participate in psychedelic-assisted therapy

Journal of Psychedelic Studies April 2, 2024 Sonia M. Brodie, Chelsea Stunden, Jay A. Olson et al.

AbstractBackground and aimsFirst responders such as firefighters and police officers often experience traumatic events as part of their work. As a result, they are more likely to have mental health issues such as post-traumatic stress disorder, depression, and anxiety compared to the general population. Psychedelic-assisted therapy has emerged as a promising avenue to alleviate these issues,...

Acid flashbacks: The psychedelic horror film post-1979

Horror Studies April 1, 2024 Payton McCarty-Simas

While the term ‘psychedelic horror film’ may seem simple on its surface, the category it describes has never been thoroughly examined and defined. This article, using Harry M. Benshoff’s ‘The short-lived life of the Hollywood LSD film’, as an entry point, will analyse recurrent examples of psychedelic horror film, focusing on the nature of their recurring appeal. Given the lack of scholarship...

Psychedelic Renaissance: Evidence and Culture

Psychiatric News April 1, 2024 Adrian Preda

Back to table of contents Previous article Next article Editor's DeskFull AccessPsychedelic Renaissance: Evidence and CultureAdrian Preda, M.D.Adrian Preda, M.D.Published Online:21 Mar 2024https://doi.org/10.1176/appi.pn.2024.04.4.39The ebb and flow of societal beliefs often resemble a pendulum's swing, oscillating between acceptance and rejection. This phenomenon is not confined to the annals...

Für ein besseres Verständnis anhaltender Wahrnehmungsstörungen nach der Einnahme klassischer Psychedelika

Fortschritte der Neurologie · Psychiatrie April 1, 2024 Stefan Borgwardt, Tomislav Majić, Mihai Avram et al.

Klassische Psychedelika wie Psilocybin, Lysergsäurediethylamid (LSD), Ayahuasca oder 5-Methoxy-Dimethyltryptamin (5-MeO-DMT) stehen wieder vermehrt im Fokus des psychiatrisch-psychotherapeutischen und neurowissenschaftlichen Interesses. Dies ist vor allem auf aktuelle klinische Studien zurückzuführen, die einen möglichen therapeutischen Nutzen von Psychedelika in der Behandlung verschiedener...