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LSD research published in 2024

Page 5 of 5: studies 81 to 91 of 91, newest first. Back to the LSD overview

Studies

Albert Hofmanns Weg zum psychotogenen LSD

2024 Frank P. Petersen

Dale gefragt wurde, wer die Isolierung des wasserlöslichen, mysteriösen Wirkstoffs aus den Keulenkopf-Sklerotien angehen könne, dachte er gleich an seinen langjährigen Kollegen und Chefchemiker Harold Ward Dudley (1887–1935) am National Institute for Medical Research. Er kannte ihn bestens von gemeinsamen Forschungsarbeiten zu Histamin, Acetylcholin und Insulin, bei denen Dudley harte Nüsse zu...

Commentary: Evidence-Informed Recommendation to Achieve Approximate Parity in the Allowed Number of Doses for Common Psychedelics.

Journal of Psychoactive Drugs 2024 Kelan Thomas, Robert L. Jesse, Nicky J. Mehtani et al. 4 citations

In recent years, policymakers have proposed and implemented regulatory changes promoting the deprioritization, decriminalization, or state-level legalization of one or more psychedelic substances, usually referencing data from clinical trials as reasons to support liberalizing drug control policies. As psychedelic policies continue to be drafted, personal possession limits may be considered for...

Lysergic acid diethylamide stimulates cardiac human H2 histamine and cardiac human 5-HT4-serotonin receptors.

Naunyn-Schmiedeberg's Archives of Pharmacology 2024 Ulrich Gergs, Hannes Jacob, Pauline Braekow et al. 16 citations

Lysergic acid diethylamide (LSD) is an artificial hallucinogenic drug. Thus, we hypothesized that LSD might act 5-HT4 serotonin receptors and/or H2 histamine receptors. We studied isolated electrically stimulated left atrial preparations, spontaneously beating right atrial preparations, and spontaneously beating Langendorff-perfused hearts from transgenic mice with cardiomyocyte-specific...

Pharmacokinetics, pharmacodynamics and urinary recovery of oral lysergic acid diethylamide administration in healthy participants.

British Journal of Clinical Pharmacology 2024 Friederike Holze, Livio Erne, Urs Duthaler et al. 12 citations

Lysergic acid diethylamide (LSD) is currently investigated for several neurological and psychiatric illnesses. Various studies have investigated the pharmacokinetics and the pharmacokinetic-pharmacodynamic relationship of LSD in healthy participants, but data on urinary recovery and confirmatory studies are missing. The present study characterized the pharmacokinetics,...

Use of Lysergic Acid Diethylamide by Major Depression Status.

JAMA Psychiatry 2024 Claire A Walsh, Lauren Gorfinkel, Dvora Shmulewitz et al. 24 citations

Renewed interest in the clinical potential of hallucinogens may lead people with depression to a generally more positive view of the use of lysergic acid diethylamide (LSD). Therefore, past-year LSD use among people with depression may be increasing in prevalence. To assess time trends in the prevalence of past-year nonmedical LSD use by past-year major depression status and the variation in...

The Rising Use of LSD among Business Managers.

Substance Use & Misuse 2024 Benjamin A. Korman 4 citations

Although studies have demonstrated that the use of lysergic acid diethylamide (LSD) is on the rise in the United States, it remains unclear how this trend looks across the hierarchical ladder of the American workforce. This is relevant given that LSD is increasingly being touted as a means of boosting creativity and performance, with mounting anecdotal evidence that business managers in...

DOI: 10.1080/10826084.2023.2267105 (opens in new tab) Full text (opens in new tab) LSD Business managers Trends Psychedelics hallucinogens +7

Longitudinal associations between psychedelic use and unusual visual experiences in the United States and the United Kingdom.

Journal of Psychopharmacology 2024 Otto Simonsson, Peter S. Hendricks, Cecilia Ud Stenfors et al.

Whereas findings from case reports and cross-sectional studies suggest that naturalistic psychedelic use may be associated with unusual visual experiences that occur after the acute pharmacological effects have subsided, such findings need to be replicated in longitudinal studies to better understand potential cause-and-effect relationships. To investigate longitudinal associations between...

Dose-dependent LSD effects on cortical/thalamic and cerebellar activity: brain oxygen level-dependent fMRI study in awake rats.

Brain Communications 2024 Ashley Ghaw, Alisha Chunduri, Arnold Chang et al. 13 citations

Lysergic acid diethylamide is a hallucinogen with complex neurobiological and behavioural effects. This is the first study to use MRI to follow functional changes in brain activity in response to different doses of lysergic acid diethylamide in fully awake, drug-naive rats. We hypothesized that lysergic acid diethylamide would show a dose-dependent increase in activity in the prefrontal cortex...

Does LSD confer lasting psychological resilience? an investigation of naturalistic users experiencing job loss.

PLoS One 2024 Benjamin A. Korman

Recent studies on classic psychedelics have suggested that their use is associated with psychological strengths and resilience, thereby conferring users a type of psychological protection relative to non-users. However, this idea has been brought into question by recent findings suggesting that lifetime users of lysergic acid diethylamide (LSD) report worse mental health during stressful...

DOI: 10.1371/journal.pone.0304991 (opens in new tab) Full text (opens in new tab) Psychedelics Mental health Unemployment Psychological resilience +1

[The nursing role in psychedelic-assisted psychotherapy].

Revue de l'infirmiere 2024 Caroline Amberger, Laurent Szczesniak

In this article, we aim to highlight the specific role of nurses in the interdisciplinary model of psychedelic-assisted psychotherapy. We argue that the plural competencies of our profession are at the heart of future issues in psychiatry and the use of psychedelics.