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Nicky J. Mehtani

6 papers in the library · 42 citations · publishing 2024-2025

Papers

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Psychedelic Augmentation of 12-Step Engagement: A Novel, Accessible Approach to Enhance Community-Based Recovery from Substance Use Disorders.

Journal of Psychoactive Drugs November 10, 2025 Nicky J. Mehtani, Maha N. Mian, Gabrielle Agin-Liebes et al. 1 citation

Amid an evolving psychedelic drug policy landscape and limitations of existing substance use disorder (SUD) treatments, a novel addiction recovery paradigm has emerged involving augmentation of 12-Step program engagement with therapeutic psychedelic use. A preliminary qualitative analysis was initiated to describe this movement by examining real-world experiences of participants in remission...

DOI: 10.1080/02791072.2025.2583960 (opens in new tab) Full text (opens in new tab) Addiction Community-based treatment Substance use disorders 12-step recovery +1

Ketamine-Assisted Recovery (KARE): protocol for an open-label pilot trial of ketamine-assisted psychotherapy for publicly insured patients with methamphetamine use disorder and HIV risks

BMJ Open August 1, 2025 Nicky J. Mehtani, B. Anderson, Irina Alexander et al.

INTRODUCTION: Methamphetamine use disorder (MeUD) is a debilitating condition with no FDA-approved pharmacotherapies that has been associated with poor neurological, psychiatric and cardiovascular outcomes, particularly among low-income populations. The use of methamphetamine also increases risks for sexually transmitted infections (STIs) by reducing behavioural inhibitions while enhancing...

DOI: 10.1136/bmjopen-2025-100775 (opens in new tab) Ketamine Protocol science Methamphetamine Open label +3

A systematic review of income and education reporting in psychedelic clinical trials

Nature Mental Health May 1, 2025 Daniel H. Grossman, Kevin R. Madden, Nicky J. Mehtani et al. 10 citations

Socioeconomic status (SES) substantially influences mental health outcomes and treatment access, yet its reporting in psychedelic-assisted therapy trials remains underexplored. Here we systematically reviewed 98 articles (49 primary trials and 49 secondary analyses) published between 2006 and 2024 examining classic psychedelics and MDMA for mental health conditions. Only 12% of primary trials...

On Minimizing Risk and Harm in the Use of Psychedelics.

Psychiatric Research and Clinical Practice February 11, 2025 Jules Evans, Marc Aixalà, Brian T Anderson et al. 18 citations

Objective: This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net. Methods: A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety. Results: The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors...

DOI: 10.1176/appi.prcp.20240128 (opens in new tab) Full text (opens in new tab) Psychedelic therapy Mental health safety Therapeutic protocols Harm reduction +1

Psilocybin-assisted therapy and HIV-related shame

Scientific Reports August 2, 2024 Jennifer Mitchell, Nicky J. Mehtani, Mallory O. Johnson et al. 9 citations

Abstract As a proposed mediator between stigma-related stressors and negative mental health outcomes, HIV-related shame has been predictive of increased rates of substance use and difficulties adhering to antiretroviral treatment among people with HIV. These downstream manifestations have ultimately impeded progress toward national goals to End the HIV Epidemic , in part due to limited success...

Commentary: Evidence-Informed Recommendation to Achieve Approximate Parity in the Allowed Number of Doses for Common Psychedelics.

Journal of Psychoactive Drugs 2024 Kelan Thomas, Robert L. Jesse, Nicky J. Mehtani et al. 4 citations

In recent years, policymakers have proposed and implemented regulatory changes promoting the deprioritization, decriminalization, or state-level legalization of one or more psychedelic substances, usually referencing data from clinical trials as reasons to support liberalizing drug control policies. As psychedelic policies continue to be drafted, personal possession limits may be considered for...