Abstract Background and Aims Mental health challenges such as depression, anxiety, and existential distress are common among individuals with terminal illness. Preliminary evidence suggests that death acceptance may protect against these issues, but there is limited research on the role of psychedelic-assisted therapy in fostering death acceptance. This scoping review aims to explore the...
Altered states of consciousness (ASC) represent a universal human capacity for accessing and transforming the subconscious mind, employed across cultures and millennia through diverse contemplative, somatic, pharmacological, ritual, and technological modalities. This comprehensive review synthesizes evidence from over 25 distinct disciplines spanning five clusters: (A) contemplative and...
Quality in SportApril 3, 2026Tetiana Savchak, S B Ivanchuk, Anhelina Kaminskaya et al.
Purpose of research: This literature-based review was created to evaluate the effectiveness of yoga and mindfulness-based interventions (MBIs) in managing chronic and acute cancer-related pain. Research materials and methods: A systematic review of literature from 2012 - 2026 across databases including PubMed, Scopus, and Web of Science was conducted. Full-text versions of Meta-Analyses,...
Abstract Background Determining health information quality on online drug platforms is crucial for revealing and shaping substance use practices. The study aims to assess the scope and quality of health-related information on the largest Polish drug forum, Hyperreal. Ultimately, the goal was to explore how the case of Hyperreal illustrates user-driven knowledge construction around drug use and...
CONTEXT: People living with serious illness frequently experience intense existential suffering related to awareness of finitude. Psychedelic-assisted therapies have been associated with reductions in death anxiety and existential distress, yet the experiential processes underlying transformations in the relationship with finitude remain insufficiently understood. OBJECTIVES: To synthesize...
Meditation-related difficulties have been systematically documented in contemporary contemplative science, yet the prescriptive resources preserved in the ancient Buddhist commentarial literature remain underutilized in comparative research. This study analyzes the case of five hundred monks in the Paramatthajotikā I’s commentary on the Karaṇīya-metta-sutta. During intensive practice, these...
Depression and psychological distress are highly prevalent among patients with cancer and are associated with impaired quality of life, reduced treatment adherence, and poorer clinical outcomes. Standard pharmacological and psychosocial interventions often demonstrate limited efficacy or delayed onset of action in oncological and palliative settings. Psilocybin-assisted therapy has recently...
IMPORTANCE: As psychedelic-assisted therapies gain clinical legitimacy, their cultural portability remains underexamined. While promising results have emerged from trials on existential distress in life-limiting illness, most protocols reflect Euro-American values. The expansion of these therapies calls for a pivot toward cultural humility and renewed attention to what constitutes a "good...
Psychological stress not only undermines quality of life for people with cancer but also fuels tumor growth. Emerging evidence from the nascent field of cancer neuroscience suggests that adrenergic signaling from direct tumor-neuron interactions drives cancer progression, resistance to treatment, and worse outcomes. Cancer neuroscientists are increasingly seeking to repurpose psychoactive...
Spiritual interventions, including meditation, prayer, mindfulness, and compassionate care, have gained increasing attention for their potential to enhance both psychological resilience and overall health. This systematic review and meta-analysis examined eight eligible studies conducted across the USA, Europe, and China to assess the impact of such interventions on key outcomes, namely anxiety...