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End-of-life distress: all studies

Page 19 of 40: studies 181 to 190 of 392, newest first. Back to the end-of-life distress overview

Research

Improving access to psilocybin-assisted therapy: barriers, challenges, and recommendations

Frontiers in Public Health January 29, 2026 Vivian W. L. Tsang, Camille Roney, Pamela Kryskow et al.

Psilocybin-assisted therapy (PAT) is an emerging intervention that combines the administration of psilocybin with structured psychological support to address profound psychological, emotional, and existential distress. Central to this model is the recognition that many forms of suffering-particularly at end of life-are relational in nature and require relational forms of healing. It is our...

DOI: 10.3389/fpubh.2026.1767210 (opens in new tab) Psilocybin Intervention counseling Existentialism Transformative learning +10

Examining the Perspectives of Key Stakeholders on the Problems, Policies, and Politics Regarding Accessing Psychedelic Interventions to Alleviate End‐of‐Life Distress

Politics &amp Policy January 24, 2026 Sarah Kratina, Robert Schwartz, Carol Strike et al. 2 citations

ABSTRACT Psychedelic interventions are not publicly available through Canada's healthcare system. Despite growing scientific evidence, public interest, and efforts to expand access to psychedelic therapies for end‐of‐life psychological suffering, Canadian policies remain restrictive. Efforts are underway to expand access, but knowledge gaps exist regarding the policy landscape in Canada. This...

THE PSYCHEDELIC RENAISSANCE: A SYSTEMATIC REVIEW OF PSILOCYBIN AND LSD IN THE TREATMENT OF PSYCHIATRIC DISORDERS

International Journal of Innovative Technologies in Social Science January 23, 2026 Jakub Klepacz, Radosław Swędrak, Marzena Swojnóg et al.

The escalating global burden of mental health disorders, coupled with the stagnation of innovation in traditional monoaminergic pharmacotherapy (e.g., SSRIs), has precipitated a critical need for novel therapeutic paradigms. This article presents a comprehensive systematic review of the so-called "Psychedelic Renaissance," focusing on the clinical resurgence of classical serotonergic...

Liminal Competence: An Original Construct for Sustainable Threshold-Dwelling in Ongoing Loss

OALib 2026 Tim Mussche 2 citations

Healthcare chaplains and clinicians increasingly encounter patients whose losses do not conclude: those in palliative trajectories, persons with progressive neurological disease, dementia caregivers, displaced persons, and incarcerated individuals.This article is a conceptual contribution that derives its construct from interdisciplinary literature rather than from new empirical data.The...

When the Body Sleeps but the Self Remains: An Autoethnographic Study of Recurrent Sleep Paralysis

Open Mind 2026 Fatema Shabbir preprint

This research project presents a six-year autoethnographic case study examining recurrent sleep paralysis through the lens of lived experience. While sleep paralysis is commonly explained through neurophysiological mechanisms—particularly REM atonia intrusion—there remains a significant gap in qualitative literature capturing how the condition is experienced subjectively over time. The purpose...

Mindfulness and Buddhist principles in oncology: Risks, misconceptions and recommendations for ethical integration.

Journal of Psychosocial Oncology 2026 Chloe Wells, William van Gordon, Paul Barrows 3 citations

Mindfulness-based interventions are gaining recognition as effective therapeutic tools for psychological distress in oncology. However, the widespread adoption of mindfulness in Western clinical contexts has raised ethical and philosophical concerns, particularly regarding the Westernisation and cultural appropriation of Buddhist wisdom. This paper examines the ethical implications of employing...

The dying-moment dream hypothesis: heaven and hell as the brain's final dream.

Frontiers in Psychology 2026 Recai Kayış

Reports of near-death experiences (NDEs), end-of-life visions (ELVs), and culturally embedded afterlife narratives frequently describe profoundly positive or distressing states. Traditional interpretations treat these phenomena as evidence of external metaphysical realms. The Dying-Moment Dream Hypothesis proposes an alternative, neurobiologically grounded explanation: that culturally...

Healthcare Providers' Perspectives on Psychedelic-Assisted Therapies Across Clinical Contexts: "I Can Offer Medical Assistance in Dying, but I Can't Prescribe Psychedelics".

Global Advances in Integrative Medicine and Health 2026 Haley D M Schuman, Raèf Mina, Sofia Barkova et al.

Healthcare providers' (HCPs) perspectives on psychedelic-assisted therapy (PAT) are critical to clinical integration but remain underexplored in Canadian palliative and oncology contexts. This study examines HCP attitudes toward ketamine, psilocybin, and MDMA, and the systemic and ethical factors influencing implementation. An exploratory qualitative study using semi-structured interviews was...

Pharmacological Management of Anxiety in End‐of‐Life Care: A Systematic Review of Benzodiazepines, Opioids, and Psilocybin

Human Psychopharmacology: Clinical and Experimental 2026 Brunno Freitas Da Costa, Paula Hartmann, Daniel Pagnin

ABSTRACT Objective Anxiety is common in patients receiving end‐of‐life care and significantly impacts their quality of life. However, pharmacological management remains challenging due to complex clinical presentations and potential side effects, emphasizing the need for systematically reviewing existing treatments. Here we aim to systematically evaluate the efficacy and safety of...