Abstract People frequently dream of recent experiences, which may reflect the consolidation of memories in the sleeping brain. Many studies demonstrate that experimentally introducing new learning prior to sleep can induce dreams of recently encoded memories. Here, for the first time, we tested whether activating a remote memory just before sleep can similarly induce participants to dream about...
SLEEP Advances2025Luis Alfredo Moctezuma, Marta Molinas, Takashi Abe1 citation
Abstract This study proposes a method to automatically identify dream experience (DE) and no experience (NE) during the sleep stage N2 of nonrapid eye movement (NREM). We investigated the use of machine learning (ML) to automatically identify when a subject is having a dream during NREM from electroencephalography (EEG) signals. We use permutation-based channel selection to identify the most...
During an acute episode of depersonalization/derealization (DP/DR), people report a complex and idiosyncratic change in their perceptual experience. Specifically, derealisation describes the experience of detachment from the external world and altered visual perception in which the surroundings look faded, foggy, or dream-like. Whilst some have argued that there may not be genuine perceptual...
Although mechanistic studies on Yoga and meditation have demonstrated their efficacy over the past few decades, very few studies have focused on the Yogic state of Samaadhi, characterized by an ultimate state of peace and happiness. In this study, we probed electrophysiological correlates of Samaadhi in a Yogi par excellence. This research was conducted in the 1980s and is now being brought to...
Dying patients can experience vivid dreams, visions or unexpected lucid episodes despite declining clinical and mental status. This review examines patient end-of-life experiences (ELEs) and their implications to the mind-brain relationship (MBR). A Scoping Review (ScR) was conducted, searching major academic databases for qualitative, quantitative, or mixed methods studies. Data were...
PLoS One2025Anne S. Fleiner, Daniel Kolnier, Nicholas Hagger-Vaughan et al.1 citation
Propofol and ketamine are widely used general anaesthetics, but have different effects on consciousness: propofol gives a deeply unconscious state, with little or no dream reports, whereas vivid dreams are often reported after ketamine anaesthesia. Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist, while propofol is a γ-aminobutyric-acid (GABAA) receptor positive allosteric...
Opioids are widely used for anesthesia and postoperative analgesia; however, their use is related to increased risks of untoward effects including hyperalgesia and chronic postsurgical pain (CPSP). We aim to compare opioid-free anesthesia (OFA) with opioid-based anesthesia (OBA) on the incidence of CPSP after video-assisted thoracoscopic surgery (VATS). This randomized controlled clinical trial...
Silene undulata is historically used for inducing vivid and prophetic lucid dreams, but limited information exists on its phytochemical composition and potential pharmacological properties. This study aimed to investigate the phytochemical composition of S. undulata through LC-MS/MS analysis and explore its potential serotonergic activity, which could support and confirm the traditional use of...
How is it that psychedelics so profoundly impact brain and mind? According to the model of "Relaxed Beliefs Under Psychedelics" (REBUS), 5-HT2a agonism is thought to help relax prior expectations, thus making room for new perspectives and patterns. Here, we introduce an alternative (but largely compatible) perspective, proposing that REBUS effects may primarily correspond to a particular (but...
This essay presents the dreams of a long-term patient over the course of treatment in order to explore the transpersonal potential of the relational unconscious—those open channels of unconscious communication between people. At a key moment, the patient brings in the therapist’s own childhood dream, serving to break a period of impasse and reset the therapy. Dreams and their interpretation...