Brain and Neurological Disorders
June 21, 2022
Abdul Wahab Alahmari
Many psychedelics drugs are praised on social media platforms like YouTube by non-experts or bias documentaries claiming that these drugs have therapeutic effects on addicted patients or clarity of the mind. The aim of this paper is to collect a neuroimaging documentation of these psychedelics’ drugs and their effect on the brain. That can be documented on MRI, CT, or any other imaging modalities.
medRxiv
June 16, 2022
Caroline L. Alves, Thaise G. L. de O. Toutain, Joel Augusto Moura Porto et al.
preprint
There is a growing interest in the medical use of psychedelic substances as preliminary studies using them for psychiatric disorders have shown positive results. In particularly, one of these substances is N,N-dimethyltryptamine (DMT) an agonist serotonergic psychedelic that can induce profound alterations in state of consciousness. In this work, we propose a computational method based on...
European Psychiatry
June 1, 2022
Johannes T. Reckweg, Natasha L. Mason, Cees van Leeuwen et al.
3 citations
Introduction 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) is a tryptamine with ultra-rapid onset and short duration of psychedelic effects. Prospective studies for other tryptamines have suggested beneficial effects on mental health outcomes. Objectives In preparation for a study in patients with depression, the present study GH001-HV-101 aimed to assess the impact of four different dose levels...
Scientific Reports
May 24, 2022
David Wyndham Lawrence, Robin Carhart-Harris, Roland R. Griffiths et al.
64 citations
Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine (N, N-DMT) experience is critical to facilitate and support ongoing research and therapeutic models targeting mental health conditions and central nervous system pathology. A qualitative analysis was conducted of all N, N-DMT experiences posted to the r/DMT Reddit community over a 10-year period from 2009 to...
bioRxiv (Cold Spring Harbor Laboratory)
May 22, 2022
Leonard Lerer, Eric Reynolds, Jeet Varia et al.
preprint
Abstract There is growing interest in the therapeutic potential of 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) for psychiatric disorders. While 5-MeO-DMT can be chemically synthesized, the parotoid gland secretions of Incilius alvarius (also known as the Colorado River or Sonoran Desert toad) contain 5-MeO-DMT and other molecules including bufotenine, bufagenins, bufotoxins, and indole...
Fieldwork in Religion
May 19, 2022
Anna Lutkajtis
Luke, David and Rory Spowers, eds. 2021. DMT Entity Encounters: Dialogues on the Spirit Molecule. Rochester, VT: Park Street Press. xiv + 370 pp. ISBN: 978-1-64411-233-5 (pbk)
Research Square
April 28, 2022
David Wyndham Lawrence, Robin Carhart-Harris, Roland R. Griffiths et al.
2 citations
preprint
Abstract Background: Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine (N, N-DMT) experience is critical to facilitate and support ongoing research and therapeutic models targeting mental health conditions and central nervous system pathology. Methods: Qualitative analysis of all N, N-DMT experiences posted to the r/DMT Reddit community over a 10-year period...
Journal of Herbmed Pharmacology
April 1, 2022
Neyder Contreras, Antistio Alvíz-amador, Isabella Manzur-Villalobos
5 citations
Introduction: The 5-HT1B receptor has a potential role in various psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder. The objective of this study was to perform docking and molecular dynamics simulation to evaluate at atomic level the behavior of N,N-dimethyltryptamine (DMT) on 5-HT1B receptor.Methods: In this study, initially, a search for DMT was performed...
Human Psychopharmacology: Clinical and Experimental
March 17, 2022
Edward James, Joachim Keppler, Thomas L Robertshaw et al.
Data sharing is not applicable to this article as no new data were created or analysed in this study.
Human Psychopharmacology: Clinical and Experimental
March 17, 2022
Rafael Lancelotta
2 citations
The author confirms that the data supporting the findings of this study are available within the article [and/or] its supplementary materials.