INTRODUCTION: The pineal gland is a photo-neuro-endocrine organ situated inside the brain, that secretes serotonin, melatonin and N,N-dymethyltriptamine. This narrative review will address the latest information gathered on this function of the gland as well as the unknown roles it may have. The different histological and pathological findings of the pineal gland have demonstrated a role in...
This article refers to:5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety
The real or perceived proximity to death often results in a non-ordinary state of consciousness characterized by phenomenological features such as the perception of leaving the body boundaries, feelings of peace, bliss and timelessness, life review, the sensation of traveling through a tunnel and an irreversible threshold. Near-death experiences (NDEs) are comparable among individuals of...
February 27, 2019Matheus Arts, Linda de Jonge, S. Petrykiv1 citation
Background: Ayahuasca, also called yagu00e9, is a psychoactive potion of various plant infusions consisting of the Banisteriopsis caapi vine, containing beta-carbolines, and the leaves of the N,N-dimethyltryptamine (DMT)-containing Psychotria viridis, which acts as a potent agonist to 5-HT2a receptors. Drinking ayahuasca has recently become very popular in shamanistic u2018healing...
Background: The surface web is a rich source of extensive data on populations of users and misusers of psychoactive substances including substances known as hallucinogens and entheogens. The internet and its social media websites can serve as a database upon which several hypotheses are applicable via thematic analytic and psychoanalytic studies. Materials and Methods: This study will deploy...
Pain is the most prevalent symptom of a health condition, and it is inappropriately treated in many cases. Here, we present a case report in which we observe a long-lasting analgesic effect produced by changa, a psychedelic drug that contains the psychoactive N,N-dimethyltryptamine and ground seeds of Peganum harmala, which are rich in β-carbolines. We describe the case and offer a brief review...
Identification of the biological features of autism is essential for designing an efficient treatment and for prevention of the disorder. Though the subject of extensive research, the neurophysiological features of autism remain unclear. One of the proposed biological causes of autism is malfunction of the pineal gland and deficiency of its principal hormone, melatonin. The main function of...
Zaburzenia psychiczne stają się plagą współczesnych społeczeństw postindustrialnych, poddanych oddziaływaniu szybko ewoluującego otoczenia cywilizacyjnego. W połowieubiegłego wieku odkrycie potencjału LSD i psylocybiny znalazło zastosowanie na gruncie psychologii, a wśród prekursorów jego wykorzystania w psychoterapii był pracownik Uniwersytetu Harvarda, twórca interpersonalnej teorii...
Archaeological studies have found evidence of ritual consumption of psychoactive plants among native cultures in South America. However, the evidence is fragmentary, preventing researchers from piecing together a coherent picture of hallucinogen use in ancient South America. Melanie Miller et al. (pp. 11207–11212) analyzed the chemical makeup of artifacts in a 1,000-year-old ritual bundle...
This chapter aimed to provide an overview of the large number of hallucinogens of natural origin. Following a literature review, the following hallucinogens were selected for a detailed description that considered their essential chemical groups: indoleamines ( N,N -dimethyltryptamine, 5-methoxy- N,N -dimethyltryptamine, bufotenine, psilocybin, and ibogaine), phenylethylamines (mescaline),...