Neuroscience & Biobehavioral Reviews
January 2020
Rafael Guimarães Dos Santos, Jaime Eduardo Cecilio Hallak
Serotoninergic hallucinogens include drugs such as lysergic acid diethylamide (LSD), dimethyltryptamine (DMT) and psilocybin. Recent trials with single/few doses of these compounds show that they induce rapid and sustained antidepressive, anxiolytic, and antiaddictive effects. These effects are also observed in religious groups using the DMT-containing brew ayahuasca. The agonist action of...
Journal of Psychoactive Drugs
2020
Ismael Eduardo Apud Peláez
22 citations
Ayahuasca is a psychoactive brew that contains N,N-dimethyltryptamine and monoamine oxidase-inhibiting alkaloids. It is originally from the Amazon rainforest, but since the 1990s it has expanded worldwide. The compound is used in different religious, spiritual, and therapeutic settings. One of its common applications is for the treatment of addiction. The current study is an assessment of the...
Human Psychopharmacology: Clinical and Experimental
2020
Patricia Acosta, Joseph J Palamar
44 citations
Abstract Objective The number of novel psychedelic phenethylamines and tryptamines has continued to increase, but little academic research has focused on the effects of these substances. We sought to determine and compare the subjective effects of various substances. Methods We conducted in‐depth interviews with 39 adults (75.4% male and 87.2% White) who reported experience using psychedelic...
December 13, 2019
Vítor Bruno
1 citation
\n Alucinógenos (ALU) são substâncias psicoativas que não induzem o indivíduo à dependência, possuem perfil de segurança de uso mais alto quando comparado a outras drogas e baixa capacidade de causar tolerância ao uso. Estudos recentes propõem o uso de ALU como tratamento a algumas doenças e transtornos relacionados ao sistema nervoso central, como a depressão, ansiedade e dependência. Dentre...
Medicines
October 18, 2019
Ana Y. Simão, Joana Gonçalves, Ana Paula Duarte et al.
36 citations
Ayahuasca is a psychoactive beverage prepared traditionally from a mixture of the leaves and stems of Psychotria viridis and Banisteriopsis caapi, respectively, being originally consumed by indigenous Amazonian tribes for ritual and medicinal purposes. Over the years, its use has spread to other populations as a means to personal growth and spiritual connection. Also, the recreational use of...
Journal of Psychedelic Studies
September 1, 2019
Avery Sapoznikow, Zachary Walsh, Kenneth W. Tupper et al.
8 citations
Background and aims Ayahuasca is a psychedelic decoction prepared from two (or more) plants containing monoamine oxidase inhibitors, N , N -dimethyltryptamine, and other chemicals. Ayahuasca has apparently been used for centuries in the Amazon basin of South America, and in recent years has increasingly been used internationally in diverse contexts. This study aims to elucidate differences...
Journal of Emergency Medicine Case Reports
July 1, 2019
Selman Yeniocak, Asım Kalkan, Tuğba Aguş et al.
3 citations
Objective: Ayahuasca tea contains N, N-dimethyltryptamine (DMT) found in the leaves of the Psychotria viridis vine and -carbolines found in Banisteriopsis caapi.Case Report: A 59-year-old man was brought to the emergency department due to hallucinations, agitated behavior, aggression , nausea and vomiting developing 1.5 h after drinking approximately one tea glassful of Ayahuasca tea....
Journal of Chromatography B
June 8, 2019
Rita C. Z. Souza, Flávia Da Silva Zandonadi, Donizete P. Freitas et al.
42 citations
Ayahuasca is a brew prepared from the water decoction of two Amazonian plants, which is legally used for religious, cultural or therapeutic activities. The potential use of ayahuasca as a natural or phytotherapeutic drug is directly linked to the action of its active compounds and their connection with the therapeutic efficacy of the beverage. In this context, the aim of the present study was...
Proceedings of the National Academy of Sciences
June 4, 2019
Melanie J Miller, Juan Albarracin-Jordan, Christine K. Moore et al.
171 citations
Over several millennia, various native plant species in South America have been used for their healing and psychoactive properties. Chemical analysis of archaeological artifacts provides an opportunity to study the use of psychoactive plants in the past and to better understand ancient botanical knowledge systems. Liquid chromatography tandem mass spectrometry (LC-MS/MS) was used to analyze...
Natural Products and Bioprospecting
May 27, 2019
Edgar Antonio Estrella-Parra, Julio Cesar Almanza-Pérez, Francisco Javier Alarcón-aguilar
57 citations
Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a "master plant." It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it stimulates creative thinking and visual creativity. Native healers of the Orinoco and Amazon basins have used traditionally ayahuasca as a healing tool...