The European Journal of Psychiatry
September 1, 2009
Celestine Okorome Mume
34 citations
Background and Objectives: Nightmare is a common sleep disorder.While a sleep disorder such as insomnia can readily be associated with psychiatric disorders, the same cannot be said of nightmare.The objective of this study was to determine the prevalence rate of nightmare in a sample of psychiatric patients, and to compare this rate with the rate obtained in age-and sex-matched healthy control...
The International Journal of Neuropsychopharmacology
September 2009
Dragoš Inta, Massimo Trusel, Marco A Riva et al.
Preclinical and clinical studies have shown that N-methyl-D-aspartate (NMDA) receptor antagonists can exert antidepressant effects. Thus, a single intravenous injection of ketamine, a non-competitive NMDA receptor antagonists, has been recently demonstrated to produce a rapid and relatively sustained antidepressant effect in patients. Therefore, the role of NMDA receptors and their signalling...
Revista Brasileira de Psiquiatria
September 2009
Lara C Assis, Gislaine T Rezin, Clarissa M Comim et al.
Clinical findings suggest that ketamine may be used for the treatment of major depression. The present study aimed to compare behavioral effects and brain Creatine kinase activity in specific brain regions after administration of ketamine and imipramine in rats. Rats were acutely given ketamine or imipramine and antidepressant-like activity was assessed by the forced swimming test; Creatine...
Journal of Forensic Sciences
September 1, 2009
Barry K. Logan
Dextromethorphan is a nonprescription antitussive which has been gaining in popularity as an abused drug, because of the hallucinogenic, dissociative, and intoxicating effects it produces at high doses. This report describes a series of eight drivers arrested for driving under the influence of the combined effects of dextromethorphan and chlorpheniramine, and a further four drivers under the...
Current Medicinal Chemistry
August 20, 2009
John S. Adams
7 citations
Pyramidal neurons in layer 5 of the cerebral cortex are involved in learning and memory and have complex connections with other neurons through a very large array of dendrites. These dendrites can switch between long term depression and long term potentiation depending on global summation of various inputs. The plasticity of the input into pyramidal neurons makes the neuronal output variable....
Brain Research Bulletin
August 14, 2009
Gislaine T Rezin, Cinara L Gonçalves, Juliana F Daufenbach et al.
Modulation and dysfunction of the glutamatergic system seems to be involved in depression. Recently a renewed interest in the glutamatergic system as a treatment option for major depression emerged by the finding that the glutamate N-methyl-D-aspartate (NMDA) antagonist ketamine leads to a rapid improvement of depressive symptoms. Several works support the hypothesis that metabolism impairment...
August 14, 2009
L. Gibson
MacIntyre (Encyclopedia of Philosophy, p. 296) voices two representative philosophical criticisms of Jung’s theorizing: (1) the existence of the collective unconscious cannot be decided by any possible observation or experiment, and (2) ontological claims about the contents of the psyche are ambiguous. Jung states, “The content of the collective unconscious is made up essentially of...
Annals of the New York Academy of Sciences
August 1, 2009
Richard P. Brown, Patricia L. Gerbarg
278 citations
Yoga breathing is an important part of health and spiritual practices in Indo-Tibetan traditions. Considered fundamental for the development of physical well-being, meditation, awareness, and enlightenment, it is both a form of meditation in itself and a preparation for deep meditation. Yoga breathing (pranayama) can rapidly bring the mind to the present moment and reduce stress. In this paper,...
Annals of the New York Academy of Sciences
August 1, 2009
Elissa S Epel, Jennifer Daubenmier, Judith T. Moskowitz et al.
324 citations
Understanding the malleable determinants of cellular aging is critical to understanding human longevity. Telomeres may provide a pathway for exploring this question. Telomeres are the protective caps at the ends of chromosomes. The length of telomeres offers insight into mitotic cell and possibly organismal longevity. Telomere length has now been linked to chronic stress exposure and...
BMJ Case Reports
July 7, 2009
Ingo Kleiter, Ralf Luerding, Gerhard Diendorfer et al.
The case of a 23-year-old mountaineer who was hit by a lightning strike to the occiput causing a large central visual field defect and bilateral tympanic membrane ruptures is described. Owing to extreme agitation, the patient was sent into a drug-induced coma for 3 days. After extubation, she experienced simple and complex visual hallucinations for several days, but otherwise largely recovered....