BMJ Case Reports
July 8, 2026
Cocoa Mudgal, H J Bodansky
A man in his 30s developed progressive multisystem organ dysfunction following 15 years of heavy recreational ketamine use. Complications included ketamine cystitis, cholangiopathy, obstructive uropathy, cardiomyopathy and mood disorder. This case illustrates chronic ketamine misuse as a cumulative multisystem toxicity.
BMJ Case Reports
November 7, 2024
Yesh Chandra Singh, Shalini Singh, Roshan Bhad et al.
Various factors limit the acceptability of methadone as an opioid agonist treatment (OAT), in which case, buprenorphine becomes the preferred alternative. The classical approach is to gradually taper methadone to a low dose and buprenorphine is initiated after some opioid-free period, which generally takes weeks. A novel approach known as 'microdosing' or the 'Bernese method' might serve as a...
BMJ Case Reports
August 14, 2024
Morven Rosemary Baker, Christopher Iain O'Shea
1 citation
Ayahuasca is a plant-based psychoactive decoction, traditionally used by indigenous Amazonian peoples, which commonly contains the hallucinogen N,N-dimethyltryptamine (DMT). There is now growing interest across the Western world in psychedelics including Ayahuasca.This case describes a previously well male with no risk factors for adverse psychiatric outcomes or forensic history. Following...
BMJ Case Reports
March 1, 2024
Clarice Ho, John R. Crawford
A previously healthy adolescent presented to the emergency department with an abrupt onset of altered mental status and abnormal behaviour, including shaking of the extremities, rocking back and forth, and non-sensical speech, after ingestion of chocolate that contained psilocybin. Neurological
BMJ Case Reports
May 1, 2022
Wiktoria Julia Kotts, David Gamble, Dana Dawson et al.
10 citations
We present a case of takotsubo cardiomyopathy following recreational ingestion of Psilocybe semilanceata (known as ‘magic mushrooms’). The patient presented with respiratory distress and pulmonary oedema responding to standard medical measures. Investigations included: echocardiogram, cardiac MRI and angiogram. Based on our search, we suggest this is only the second recognised case in the...
BMJ Case Reports
November 25, 2019
Marissa Ginette Danielle Vive, Galia Valentinova Anguelova, Sjoerd Duim et al.
A 26-year-old man presented at the emergency department with confusion and decreased consciousness after several days of vomiting. In the preceding 6 months, he had used a 2-litre tank of nitrous oxide (N2O) weekly. His metabolic encephalopathy was caused by hyperammonaemia which probably resulted from interference of N2O-induced vitamin B12 deficiency with ammonia degradation. A catabolic...
BMJ Case Reports
March 7, 2019
Geoffrey Peter Ronan, Nicola Ronan, Siobhan Mcgettigan et al.
4 citations
A 26-year-old cachectic man presented with an altered mental status. He was agitated, tremulous, hyperthermic and diaphoretic with largely dilated pupils. Collateral history revealed acute ingestion of 3,4-methylenedioxymethamphetamine on a background of chronic drug abuse. His condition deteriorated requiring sedation and intubation with transfer to the intensive care unit. A diagnosis of...