Southeastern Archaeology
March 13, 2022
J. Blitz, D. Bodoh
ABSTRACT A previously unreported Depression-era excavation at the Walling II site on the Tennessee River, Alabama, revealed a context that may provide insight into Mississippian shamanic ritual. Mound A, a low earthen mound, was erected over the remains of a small circular structure, followed by the burial of a single person accompanied by a human effigy smoking pipe, human calvaria, and other...
International Journal of Environmental Research and Public Health
March 13, 2022
Yolanda Álvarez-Pérez, Amado Rivero-Santana, Lilisbeth Perestelo-Pérez et al.
Meditation is defined as a form of cognitive training that aims to improve attentional and emotional self-regulation. This systematic review aims to evaluate the available scientific evidence on the effectiveness and safety of mantra-based meditation techniques (MBM), in comparison to passive or active controls, or other active treatment, for the management of mental health symptoms. MEDLINE,...
Brain Sciences
March 12, 2022
Anya Ragnhildstveit, Matthew Slayton, Laura Kate Jackson et al.
Eating disorders (EDs) are serious, life-threatening psychiatric conditions associated with physical and psychosocial impairment, as well as high morbidity and mortality. Given the chronic refractory nature of EDs and the paucity of evidence-based treatments, there is a pressing need to identify novel approaches for this population. The noncompetitive N-methyl-D-aspartate receptor (NMDAr)...
Australian & New Zealand Journal of Psychiatry
March 12, 2022
Steve Kisely, Mark Connor, Andrew A Somogyi et al.
36 citations
Objectives: There is an increasing interest in combining psilocybin or methylenedioxymethamphetamine with psychological support in treating psychiatric disorders. Although there have been several recent systematic reviews, study and participant numbers have been limited, and the field is rapidly evolving with the publication of more studies. We therefore conducted a systematic review of PubMed,...
Journal of Fungi
March 11, 2022
Elaine Meade, Sarah Hehir, Neil J. Rowan et al.
24 citations
Mushrooms have been used as traditional medicine for millennia, fungi are the main natural source of psychedelic compounds. There is now increasing interest in using fungal active compounds such as psychedelics for alleviating symptoms of mental health disorders including major depressive disorder, anxiety, and addiction. The anxiolytic, antidepressant and anti-addictive effect of these...
Research Square
March 8, 2022
Gabriella Smedfors, Elliot J. Glotfelty, Negar Kalani et al.
8 citations
preprint
Abstract Psilocybin is a psychedelic substance approaching clinical use. The drug has long-lasting effects after single or multiple administrations and enhances structural plasticity in the brain. Little is known if the plasticity inducing effects of psilocybin could be timed to other treatments and promote a larger effect. We investigated the effect of psilocybin on cultured mouse hippocampal...
Saúde e Desenvolvimento Humano
March 7, 2022
Maria Eduarda Kegler Ramos, João Pedro Popilniski Strapasson, Cassiano Mateus Forcelini et al.
1 citation
Introdução: As vicissitudes da vida moderna, as instabilidades sociais, econômicas e comportamentais tem feito com que o consumo de chás, medicamentos, drogas e álcool tenha aumentado como alternativa de fuga dos problemas do dia-a-dia. Nos últimos anos, alguns estudos mostraram um potencial ansiolítico e antidepressivo do chá de Ayahuasca, baseado em relatos de adeptos de seitas religiosas que...
C&EN Global Enterprise
March 7, 2022
Bethany Halford
Over the past decade, psychedelic compounds like psilocybin and ecstasy have emerged as potentially life-changing treatments for mental illnesses, including major depressive disorder and posttraumatic stress disorder. Read on to learn how some companies are trying to bring these once-demonized drugs to market and how others are hoping to use chemistry to eliminate their hallucinogenic effects—a...
Contemporary Clinical Trials Communications
March 6, 2022
Anka A Vujanovic, Antoine Lebeaut, Maya Zegel et al.
Mindfulness-based interventions have demonstrated efficacy with regard to diverse psychological symptoms across populations. Few studies have evaluated the efficacy of mindfulness-based interventions for firefighters. This pilot randomized clinical trial (RCT) is designed to determine the preliminary efficacy, feasibility, and acceptability of a novel mindfulness-based workshop (entitled...
Frontiers in Psychology
March 4, 2022
Agnieszka D. Sekula, Luke A. Downey, Prashanth Puspanathan
27 citations
Psychotherapy with the use of psychedelic substances, including psilocybin, lysergic acid diethylamide (LSD), ketamine, and 3,4-methylenedioxymethamphetamine (MDMA), has demonstrated promise in treatment of post-traumatic stress disorder (PTSD), anxiety, addiction, and treatment-resistant depression. Psychedelic-assisted psychotherapy (PP) represents a unique psychopharmacological model that...