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Steve Kisely

3 papers in the library · 58 citations · publishing 2020-2023

Papers

A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders

Australian & New Zealand Journal of Psychiatry March 12, 2022 Steve Kisely, Mark Connor, Andrew A Somogyi et al. 36 citations

A systematic review of randomized controlled trials found that MDMA and psilocybin, given with psychological support, may reduce symptoms in highly selected populations under close supervision. The strongest evidence was for MDMA in post-traumatic stress disorder, with a large effect compared to active controls (standardized mean difference = -0.86). Psilocybin showed small benefits for social anxiety in adults with autism and was as effective as escitalopram for long-standing depression on the primary outcome, though most secondary benefits were not significant after correction. Both drugs were well tolerated, but overall certainty of evidence was low or very low.

DOI: 10.1177/00048674221083868 (opens in new tab) Psilocybin Anxiety Psychiatry Meta-analysis +3

Mindfulness-based cognitive therapy experiences in youth with inflammatory bowel disease and depression: findings from a mixed methods qualitative study

BMJ Open November 5, 2020 Tatjana Ewais, Jake Begun, Maura Kenny et al.

Youth with inflammatory bowel disease and depression who completed an adapted mindfulness-based cognitive therapy group programme described the experience as healing and transformative. Four themes emerged: connectedness and shared understanding, growing in wisdom, therapeutic alliance, and barriers to mindfulness practice. Participants perceived peer connection as essential for learning mindfulness skills, which in turn strengthened that connection. Barriers included fatigue, depression, time, and travel constraints. The findings help interpret the results of the larger randomized controlled trial and inform future MBCT studies in this cohort.

DOI: 10.1136/bmjopen-2020-041140 (opens in new tab) Full text (opens in new tab)