Journal of Fungi
July 2, 2026
Amiel Sharchaton, Shilat Parsha, Sara P. Azerrad et al.
Psilocybin-producing mushrooms exhibit considerable biochemical diversity, yet the extent of variability among strains within a single species under standardized conditions remains insufficiently characterized. In this study, we quantified psilocybin, psilocin, baeocystin, norbaeocystin, aeruginascin, and norpsilocin in the fruiting bodies of 14 distinct strains of Psilocybe cubensis. The...
Journal of Fungi
April 7, 2026
Eyal Kurzbaum, Tomáš Páleníček, Amiel Sharchaton et al.
correction
In the original publication [...].
Journal of Fungi
January 28, 2025
Eyal Kurzbaum, Tomáš Páleníček, Amiel Shrchaton et al.
11 citations
Psilocybe cubensis, a widely recognized psychoactive mushroom species, has played a significant role in both historical and modern therapeutic practices. This review explores the complex interplay between genetic diversity, strain variability and environmental factors that shape the biosynthesis of key psychoactive compounds, including psilocybin and psilocin. With many strains exhibiting...
Journal of Fungi
January 7, 2025
Xi-Xi Han, Dorji Phurbu, Bin Cao et al.
2 citations
The Qinghai-Xizang Plateau, known for its high altitude, geological history of plate collision, crustal uplift, and special ecology factors, provides an ideal environment for studying fungal biodiversity in extreme environmental conditions. Some species within the Conocybe, containing secondary metabolites such as psilocybin, phallotoxins, and amatoxins, have potential medicinal value for...
Journal of Fungi
March 18, 2024
Wen-Qiang Yang, Mao-Qiang He, Dorji Phurbu et al.
3 citations
The species of Gymnopilus (Hymenogastraceae, Agricales) are commonly recognized as wood-decaying fungi. Certain members of this genus have been identified as psilocybin-producing mushrooms. Gymnopilus exhibits a diverse range and has a global distribution. In this study, a total of seventy-eight specimens were gathered from ten provinces in China. A comprehensive molecular phylogenetic analysis...
Journal of Fungi
August 18, 2022
Sen Yao, Chuanzheng Wei, Hui Lin et al.
6 citations
As a potential medicine for the treatment of depression, psilocybin has gradually attracted attention. To elucidate the molecular mechanism regulating psilocybin synthesis in Gymnopilus dilepis, ultra-performance liquid chromatography (UPLC) was used to detect the changes in psilocybin content after S-adenosyl-l-homocysteine (SAH) treatment and the changes of psilocybin content in different...
Journal of Fungi
June 2, 2022
Curro Polo-Castellano, José A. Álvarez, Miguel Palma et al.
19 citations
Hallucinogenic fungi, mainly those from the Psilocybe genus, are being increasingly consumed even though there is no control on their culture conditions. Due to the therapeutic potential as antidepressants and anxiolytics of the alkaloids that they produce (psilocin and psilocybin), some form of control on their production would be highly recommended. Prior to identifying their optimal culture...
Journal of Fungi
March 11, 2022
Elaine Meade, Sarah Hehir, Neil J. Rowan et al.
24 citations
Mushrooms have been used as traditional medicine for millennia, fungi are the main natural source of psychedelic compounds. There is now increasing interest in using fungal active compounds such as psychedelics for alleviating symptoms of mental health disorders including major depressive disorder, anxiety, and addiction. The anxiolytic, antidepressant and anti-addictive effect of these...