Journal of Psychedelic Studies
November 20, 2023
Tahlia R. Harrison
23 citations
Abstract Background and aims Psychedelic-assisted therapy (P-AT) has been shown to reduce post-traumatic stress disorder (PTSD), depression, and anxiety symptoms, and is likely to be approved in the United States (US) in the coming years. However, concerns about participant safety in these early trials have surfaced, including allegations of sexual misconduct. This paper aims to illuminate how...
Journal of Medicinal Chemistry
November 20, 2023
Kaveh Matinkhoo, Lisa Yu, David Press et al.
18 citations
The psychedelic prodrug psilocybin has shown therapeutic benefits for the treatment of numerous psychiatric conditions. Despite positive clinical end points targeting depression and anxiety, concerns regarding the duration of the psychedelic experience produced by psilocybin, associated with enduring systemic exposure to the active metabolite psilocin, pose a barrier to its therapeutic...
European Psychiatry
November 17, 2023
Kerem Böge, Inge Hahne, Niklas Bergmann et al.
Introduction The therapeutic effectiveness of mindfulness-based interventions (MBIs) has been shown for various mental disorders. However, for schizophrenia spectrum disorders (SSD), only a few trials have been conducted, mostly in outpatient settings. Objectives This study aimed to investigate feasibility, acceptability, and preliminary effectiveness of a four-week mindfulness-based group...
European Psychiatry
November 17, 2023
K. Beck, Atheeshaan Arumuham, S. Brugger et al.
1 citation
Introduction N-Methyl-D-Aspartate Receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. Objectives Our aim was to determine if NMDAR availability was lower in patients with first episode psychosis compared to healthy controls. Methods To address this, we studied 40 volunteers (21 patients with first episode psychosis and 19 matched...
European Psychiatry
November 17, 2023
M. I. Husain, Daniel M. Blumberger, David Castle et al.
Introduction During the last decade there has been a resurgence of interest on the use of psychedelics as novel treatments for mental disorders, including treatment-resistant depression (TRD). Psilocybin, the chemical component of “magic mushrooms”, has been administered with psychotherapy in randomized clinical trials (RCTs) showing large and sustained antidepressant effects. As the use of...
Psychoactives
November 17, 2023
Anna Beatriz Vicentini, Lucas Silva Rodrigues, Giordano Novak Rossi et al.
4 citations
Alcohol is the recreational drug most frequently consumed, and its high frequency of use can lead to worsening social, psychological, and domestic issues. The age group most susceptible to alcohol dependence is 18- to 24-year-old youths, demanding interventional tools to target early involvement risks. Ayahuasca seems to be a promising therapeutic tool since evidence suggests it presents...
Nursing
November 17, 2023
In Brief Lorazepam associated with worse progression-free survival... Examining long-term medication effects... The co-treatment approach improves efficacy... Article details FDA's questionable approval... Updates to toxicity diagnosis and management... Identifying children with acute sinusitis who are likely to benefit from antibiotics... Psilocybin as a novel Intervention for depression
Journal of Psychedelic Studies
November 16, 2023
Danelle Jones
48 citations
Recent years have seen a global explosion in the field of psychedelic research, popularizing of use of non-ordinary states of consciousness to aid in PTSD, anxiety and depression, end of life and a growing sense that the use of substances like MDMA, psilocybin and others may become mainstream approaches to treating persistent challenges in these marginalized populations.As we destigmatize these...
Psychological Reports
November 16, 2023
Akeesha Simmons, Marissa Ferry, Michael Christopher
6 citations
Racially minoritized adults lack equal representation in research and experience disparities in healthcare. Little is known about which trait-level factors may help mitigate negative and promote positive psychological health among adults from these communities. The aim of this study was to assess the differential impact of dispositional mindfulness, self-compassion, and resilience in predicting...
Psychological Reports
November 16, 2023
Grazia Mirabito, Paul Verhaeghen
8 citations
It is often assumed that changes in state mindfulness coupled with a decrease in intrusive thinking (e.g., rumination or worry) are the crucial ingredients in mindfulness interventions. We investigate this claim by examining within-person day-to-day changes and causal relationships among these changes in state measures of mindfulness, cognitive interference (a measure of intrusive thinking),...