Schizophrenia Bulletin
August 20, 2026
Sofia Francesca Aprile, Alessandro Rodolico, Djordje Basic et al.
Schizophrenia spectrum disorders are typically described using positive and negative symptoms, yet standard diagnostic systems may not reflect the full range of how individuals experience the disorder. We hypothesized that synthesizing first-person accounts would yield a broader, clinically useful symptom framework that better represents lived experience. We performed a systematic review and...
Molecular Psychiatry
May 29, 2026
Mickael Eskinazi, Rayan Nasserdine, Romane M Cusin et al.
Serotonergic psychedelics are increasingly investigated as treatments for affective disorders. Concerns persist regarding their potential to induce hypomania or mania, particularly in individuals with bipolar spectrum vulnerability. Whether these substances precipitate transient mood switches or contribute to persistent bipolar illness or diagnostic transition remains unclear. We conducted a...
Schizophrenia
April 30, 2026
Marco Zierhut, S. Koop, Niklas Bergmann et al.
This study investigates changes in stress parameters in individuals with schizophrenia spectrum disorders participating in mindfulness-based group therapy (MBGT). N = 45 participants were randomised to MBGT or Treatment as Usual over four weeks. Before and after each session, psychological and biological stress markers by self-rating scales and cortisol saliva samples were assessed in the...
Schizophrenia Research
March 13, 2026
Michel Sabé, Paul Grof, Nathan Sackett et al.
1 citation
Serotonergic psychedelics are re-emerging as therapeutic candidates across psychiatry, particularly for treatment-resistant depression. Their rapid and sustained antidepressant effects, alongside evidence for neuroplastic, dopaminergic, and glutamatergic modulation, have prompted interest in whether they could address depressive and negative symptoms in schizophrenia spectrum disorders (SSDs)....
Frontiers in Psychology
2026
Niklas Bergmann, Ingmar Conell, Inge Hahne et al.
Cognitive fusion, a key construct in Acceptance and Commitment Therapy (ACT), describes the overidentification with internal thoughts that compromises psychological flexibility and contributes to maladaptive emotion regulation. Cognitive defusion techniques aim to reduce this entanglement, promoting adaptive functioning and improved mental health. This study examined the psychometric properties...
Scientific Reports
September 23, 2025
Daniel Heppt, Niklas Bergmann, Ingmar Conell et al.
The present article explores the relationship between mindfulness meditation and personality. Based on a substantial body of research, mindfulness has been shown to have significant associations with personality. Recent research suggests that mindfulness meditation may influence personality traits in accordance with the Five Factor Personality Model. To examine this, we investigated whether...
Schizophrenia Research
July 1, 2025
Antonia Meinhart, Annika Schmueser, Steffen Moritz et al.
4 citations
Mindfulness- and acceptance-based interventions (MBIs/ABIs) for persons with schizophrenia spectrum disorders (SSD) aim to cultivate purposeful attention, mind-body awareness, and targeted action-taking. This systematic meta-review assessed the current body of evidence regarding the effects of MBIs/ABIs for SSD symptoms. The study was registered with PROSPERO (CRD42024535284) on June 3, 2024....
Asian Journal of Psychiatry
June 26, 2025
Adi Sulstarova, Luise Scheuerlein, Silvia Monari et al.
4 citations
Psychedelics are increasingly used in the general population, yet they are associated with increased risk of psychosis in a minority of users that can experience psychedelic-induced psychosis (<1 % in controlled trial settings). In contrast, the evidence regarding the treatment of psychedelics-induced psychosis remains to date scarce. We conducted a PRISMA 2020-compliant systematic review...
Scientific Reports
June 4, 2025
Inge Hahne, Julia Segerer, Marco Zierhut et al.
3 citations
The effectiveness of mindfulness-based interventions (MBIs) in enhancing mental well-being and reducing positive, negative, and depressive symptoms in schizophrenia spectrum disorders (SSD) has been increasingly supported by evidence. However, the underlying mechanisms of MBIs require further examination. Psychological flexibility (PF), typically assessed through cognitive fusion, has been...
Mindfulness
May 17, 2025
Michel Sabé, Chaomei Chen, Davy Vancampfort et al.
7 citations
Abstract Objectives We conducted a scientometric analysis on mind–body interventions to assess themes and trends in recent decades, providing insights for prospective research directions. Our systematic search, completed on 1 November, 2023, encompassed the Web of Science Core Collection and focused on scientific publications related to contemplative practices: Mindfulness, Yoga, Qi-gong,...
Molecular Psychiatry
March 1, 2025
Michel Sabé, Adi Sulstarova, Alban Glangetas et al.
39 citations
Persons with schizophrenia are excluded from psychedelic-assisted therapy due to concerns about the risk of triggering or worsening psychosis. However, there is limited meta-analytic data on the risk of psychedelic-induced psychosis in individuals with pre-existing psychotic disorders. We conducted a systematic review, meta-analysis, and overview of reviews to assess the incidence of...
Schizophrenia Bulletin
November 16, 2024
Inge Hahne, Marco Zierhut, Niklas Bergmann et al.
3 citations
The efficacy of yoga as an adjunctive treatment for schizophrenia spectrum disorders (SSD) has garnered interest. While yoga may positively influence various symptom domains, further investigation is needed due to the limited number, quality, and generalizability of studies. This study assessed the feasibility and acceptability (primary outcome) of a yoga-based group intervention (YoGI)...
Schizophrenia Research
February 1, 2024
Michel Sabé, Raoul Kohler, Natacha Perez et al.
Mindfulness-based interventions (MBIs) have emerged as secular practices, including elements of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT). While MBIs have been widely adopted for physical and mental illness, only a few available programs are explicitly adapted for psychosis. However, previous reviews have reported the vital heterogeneity regarding...
Psychiatry Research
December 1, 2023
Kerem Böge, David J Hallford, Matthias Pillny
9 citations
The precise nature of the relationship between mindfulness, psychological flexibility (PF) and psychopathology in schizophrenia spectrum disorders (SSD) remains largely unclear and warrants further investigation. We recruited 43 persons with SSD and 43 controls. Our findings revealed that SSD showed lower mindfulness and PF than controls. Mindfulness was associated with higher PS, anticipatory...
European Psychiatry
November 17, 2023
Kerem Böge, Inge Hahne, Niklas Bergmann et al.
Introduction The therapeutic effectiveness of mindfulness-based interventions (MBIs) has been shown for various mental disorders. However, for schizophrenia spectrum disorders (SSD), only a few trials have been conducted, mostly in outpatient settings. Objectives This study aimed to investigate feasibility, acceptability, and preliminary effectiveness of a four-week mindfulness-based group...
Frontiers in Psychiatry
February 7, 2023
Laura Töbelmann, Inge Hahne, Theresa Schulze et al.
Background: Research exploring the effects of yoga therapy (YT) on individuals with schizophrenia spectrum disorders (SSD) is scarce. Therefore, the current study aimed to explore possible mechanisms of actions and processes, as well as adverse effects of a novel yoga-based group intervention (YoGI) for in-patients with SSD in a German university hospital setting. Material and methods: A...
Frontiers in Psychology
September 3, 2021
Niklas Bergmann, Eric Hahn, Inge Hahne et al.
Background: Schizophrenia spectrum disorders (SSD) are frequently accompanied by comorbid depressive and anxiety symptoms, as well as impaired quality of life (QoL). A growing body of evidence has demonstrated the relevance of mindfulness for SSD in recent years. The study examined the association between mindfulness, depression, anxiety, and QoL.Materials and Methods: A total of 83...
Schizophrenia Research
January 9, 2021
Kerem Böge, Inge Hahne, Niklas Bergmann et al.
Background: A Growing body of literature indicates therapeutic effectiveness of mindfulness for mental disorders. Only few trials have been conducted with schizophrenia spectrum disorders (SSD), mostly in outpatient settings. Primary objective was to assess feasibility, acceptability, and preliminary outcomes of mindfulness-based group therapy (MBGT) for in-patients with SSD. Methods: A...