Abstract Virtually all of the world’s major spiritual and religious traditions incorporate elements of meditation or contemplative prayer, although the nature, prominence, and precise features of such practices vary between traditions. Neuroscientific findings indicate that meditation is associated with significant, enduring alterations in patterns of activity in specific brain areas. These, in...
Objective: Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have varying pharmacological actions with differential effects on acute and extended affective states, incuding anxiety. We aimed to study these effects on anxiety in legal market forms of cannabis. Method: This study makes use of a nonequivalent control group quasiexperimental design. Forty-two participants with anxiety symptions...
: Psychedelics are currently being examined once more as potential remedies for untreatable biological illnesses after decades of research problems. They are frequently regarded to be physically safe and do not frequently lead to dependency or addiction. The use of psychedelic substances in the treatment of mental illness and the adoption of the Substance Act of 1970 has classified psychedelic...
Psychedelics, such as psilocybin, mescaline and lysergic acid diethylamide (LSD), are psychoactive substances that induce alterations in cognition, perception and sensory processing. Studies in rodent models and healthy human volunteers highlight the serotonin 5-HT2A receptor’s pivotal role in mediating hallucinogenic effects. More recent findings indicate that psychedelics induce lasting...
This article offers a flexible method for analyzing drug representations in video games as they map onto lived social realities outside the game with a particular focus on US cultures. While drugs have received ample attention in popular culture studies—especially in film and television studies—game studies has been slow to produce systematic analyses of these important cultural artefacts...
Perceived ethnic discrimination is known to be associated with anxiety and depression, and in turn, anxiety and depression are known to be associated with nightmare frequency and distress. This elicits a question: is perceived ethnic discrimination associated with nightmare frequency and distress? In this study, 179 female university students from the United Arab Emirates were assessed to...
Approximately one-third of Gulf War veterans suffer from Gulf War Illness (GWI), which encompasses mood disorders and depressive symptoms. Deployment-related exposure to organophosphate compounds has been associated with GWI development. Epigenetic modifications have been reported in GWI veterans. We previously showed that epigenetic histone dysregulations were associated with decreased...
Cancer ResearchJanuary 16, 2024Kelsey Klute, Lou Lukas, Soonjo Hwang et al.2 citations
Abstract Background: Psychological distress is a common reaction to a cancer diagnosis and its treatment. Distress impacts quality of life, adherence to treatment, decision making and survival. Patients with pancreatic adenocarcinoma (PDAC) experience exceptionally high rates of psychological distress, most commonly depression, anxiety and suicidality. Psilocybin, a serotonergic psychedelic...
Postoperative depression (POD) and postoperative cognitive dysfunction (POCD) have placed heavy burden on patients’ physical and mental health in recent years. Sleep disturbance before surgery is a common phenomenon that has been increasingly believed to affect patients’ recovery, especially in aged patients, while little attention has been paid to sleep disruption before surgery and the...
Common mental health pathologies such as depression, anxiety, addiction, and PTSD have recently seen treatment inroads. These issues share a phenomenological core—a dissociative quality that involves the disintegration of self and other. Interestingly, some of the most effective treatments of these pathologies are themselvesacutely dissociative. For example, psychedelic therapy has been...