Skip to content

Depression: all studies

Page 553 of 1,036: studies 5,521 to 5,530 of 10,358, newest first. Back to the depression overview

Research

Self-inflicted transorbital intracranial foreign body following ingestion of hallucinogenic psilocybin mushrooms.

American journal of ophthalmology case reports September 1, 2025 Abigail M Blanton, Pooja Parikh, Scott Zhou et al. 3 citations

Self-inflicted penetrating orbital trauma is a rare ophthalmologic emergency requiring timely intervention and neurological monitoring to identify and treat any possible intracranial complications and to prevent irreversible vision loss. This case report aims to describe a fatal case of self-inflicted ocular trauma following the consumption of psilocybin mushrooms, necessitating urgent...

DOI: 10.1016/j.ajoc.2025.102359 (opens in new tab) Full text (opens in new tab) Neurosurgery Ocular trauma Transorbital foreign body Eye injury +19

The effect of reflective image meditation on depressive affect in middle-aged men: A single-case study

Journal of Meditation based Psychological Counseling August 31, 2025 Yuri Jang

This study explores the depression experience of a middle-aged male with depressive affect and aims to identify the impact of a Reflective Image Meditation (RIM)-based meditation counseling intervention on his emotional state through a single-case study. To this end, an 8-session meditation counseling program, incorporating RIM to help the participant observe mental phenomena as they are,...

Evaluating the effectiveness of transcendental meditation on mental health and resilience of paramedicine students - a randomised controlled pilot study.

Scientific Reports August 29, 2025 Abbie L Little, Malcolm Boyle

Paramedics worldwide have a higher prevalence of PTSD, anxiety, and depression than the general population. Paramedicine students predominately enter the profession without preventative techniques to manage stress, depression and fatigue. The objective of this study was to examine the effect of Transcendental Meditation (TM) on the well-being and resilience of paramedicine students. A pilot...

The post-marketing safety of Esketamine among older adults(≥ 65): an real-world pharmacovigilance study.

BMC Pharmacology and Toxicology August 29, 2025 Bin Deng, Zhiwen Fu, Linjie Li et al. 3 citations

AIMS: This study aims to investigate the safety profile of Esketamine, with a particular focus on comparing adverse events (AEs) between adults (< 65 years) and older adults (≥ 65 years) using data from the FDA Adverse Event Reporting System (FAERS). METHODS: We conducted a comprehensive analysis of FAERS data from 2019 to 2024, identifying 6,452 Esketamine-related AE reports. After removing...

Psilocybin-occasioned Mystical-Type Experiences and Mental Wellness

August 29, 2025 Romesha Uduwawela

<p><strong>Psilocybin, the psychoactive compound found in certain mushrooms, has gained increasing attention for its potential therapeutic applications in mental health treatment. While clinical research highlights its efficacy in alleviating mental disorders, such as depression, anxiety, PTSD, and substance use disorders, much remains to be known about the role of acute doses of psilocybin...

Investigating the safety and tolerability of single-dose psilocybin for post-traumatic stress disorder: A nonrandomized open-label clinical trial

Journal of Psychopharmacology August 29, 2025 Niall M. Mcgowan, James Rucker, Rachel Yehuda et al. 10 citations

Background: Post-traumatic stress disorder (PTSD) is a debilitating condition for which there are few efficacious treatments. Psilocybin is being studied for use in treatment-resistant depression but has not yet been investigated in PTSD. Aims: The trial’s primary outcome was to investigate the safety and tolerability of single-dose psilocybin in participants with PTSD. Methods: This was a...

Effects of Psychedelic Drug Use on Neurocognitive Function and Psychological and Social Quality of Life Domains: An International Online Study

medRxiv August 28, 2025 Franziska Stadler, Johan Saelens, Ioline D. Henter et al. preprint

This international online study (N=759) examined the acute, subacute, and long-term effects of psychedelic drug use on cognitive performance and mental health. Participants completed cognitive tasks assessing working memory, selective attention, and visual/spatial perception, as well as questionnaires assessing mental health outcomes and quality of life. Based on self-reported substance use,...

DOI: 10.1101/2025.08.27.25334164 (opens in new tab) Full text (opens in new tab) Neurocognitive Quality philosophy Function biology Drug +8

Meditative Practices and Mental Wellness: Indian Thought and Perspective

Advanced International Journal for Research August 27, 2025 Seema Rath

Mental health has emerged as a global concern in the 21st century, marked by rising cases of anxiety, depression, and stress-related disorders. Amidst this psychological crisis, the ancient Indian practice of meditation has garnered renewed attention. Rooted in profound philosophical systems like Ved?nta, S??khya, Yoga, and Buddhism, meditation is not merely a therapeutic tool but a...

The Science of Self: A Bibliometric and Pragmatic Analysis of Yoga, Meditation, And Wellbeing in The Contemporary Scientific Landscape

International Journal of Basic and Applied Sciences August 27, 2025 Pallabi Mukherjee -, Ankita Sharma, Vinita Ramchandani et al.

The research paper uses bibliometric analysis to analyze worldwide trends of yoga and ‎meditation research between the years 2010 and 2025. With citation and co-citation analysis, ‎the paper establishes top authors, nations, and repeating patterns. Results reveal consistent ‎growth in publications, highest between 2020–2022, spurred by post-COVID health ‎consciousness and India's 2020 National...

Ketamine's Therapeutic Role in Substance Use Disorders: A Narrative Review.

NeuroSci August 27, 2025 Alexander Thomas, R Andrew Chambers 4 citations

Interest in ketamine as a novel treatment for substance use disorders (SUDs) has been increasing due to its N-methyl-D-aspartate (NMDA) glutamate receptor antagonism and mounting evidence that glutamate neurotransmission is involved in the pathogenesis of both depression and addictions. This narrative review provides an outline of clinical evidence reported in the literature from the 1970s to...

DOI: 10.3390/neurosci6030083 (opens in new tab) Full text (opens in new tab) Ketamine Nmda n-methyl-d-aspartate Case reports Cohort studies +3