International Journal of Applied Research
2026
U Vijayabanu, Aswathi Bimal
Meditation and spiritual practices have moved from the margins of medical interest into the center of contemporary mental health research, with a rapidly growing body of randomized trials, neuroimaging studies, and systematic reviews. Evidence from programs such as Mindfulness Based Stress Reduction, yoga based interventions, Transcendental Meditation, loving kindness practices, and mantra...
Frontiers in Digital Health
2026
Judith Borghouts, Elizabeth V Eikey, Cinthia De Leon et al.
Digital mental health interventions (DMHIs), such as mindfulness-based apps, have become popular mental health resources and can be associated with benefits such as reducing stress, anxiety, and depression. However, there are limited data on the impact of DMHIs on improving mental health outside of controlled research settings, and what factors may facilitate or inhibit such potential impact....
Frontiers in Psychiatry
2026
Agnieszka Suchocka Capuano
Modern psychotherapy increasingly integrates multimodal and process-based approaches designed to respond to the complexity of contemporary clinical presentations. This paper introduces a three-pillar psychotherapeutic model combining (1) a revised cognitive behavioral foundation, (2) consciousness activation techniques derived from hypnosis, and (3) yoga-inspired postural and interoceptive...
Current Topics in Behavioral Neurosciences
2026
Ricarda Evens, Abdo Uyar, Tomislav Majić
The subacute period following the use of classic psychedelics is often marked by an "afterglow" - a state characterized by elevated mood; enhanced psychological well-being; increased emotional openness toward self, others, and nature; and sometimes a heightened sense of clarity and existential meaning. From a neurobiological perspective, subacute psychedelic states have been associated with...
Expert Opinion on Drug Metabolism & Toxicology
2026
Yang Jing Zheng, Christine E. Dri, Sabrina Wong et al.
Dextromethorphan/Buproprion (DXM/BUP) has received breakthrough FDA approval in August 2022 as a rapid-acting antidepressant. DXM/BUP is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist and sigma-1 receptor agonist, with bupropion (BUP), a norepinephrine/dopamine reuptake inhibitor and cytochrome P450 2D6 (CYP2D6) inhibitor. As DXM/BUP moves closer to widespread clinical use for...
Current Topics in Behavioral Neurosciences
2026
Matthias Michal
Depersonalization (DP) and Derealization (DR) refer to perceptual changes of "as-if-character" where the self (→DP) or the surroundings (→DR) are experienced as unreal. These symptoms are highly prevalent in individuals with mental disorders. If these symptoms persist most of the day for months, the diagnosis of depersonalization-derealization-disorder (DDD) is likely. DDD is a common disorder...
International journal of clinical and health psychology : IJCHP
2026
Julia Maruani, Nathan Martins, Emmanuelle Clerici et al.
Nightmare Disorder characterized by recurrent dysphoric dreams is strongly associated with major depressive episodes (MDE) and suicidal risk. Imagery rehearsal therapy (IRT) is the standard treatment for nightmares, but its effectiveness in individuals with MDE remain understudied. This study evaluated whether IRT is associated with greater improvement in nightmare symptoms compared to sleep...
Journal of Psychopharmacology
2026
Jack E Henningfield, Sandra D Comer, Matthew L Banks et al.
5 citations
Abuse potential assessment of drugs with central nervous system activity is a critical component of the development of new medications for regulatory filings for approval worldwide. These new drug applications typically include recommendations for scheduling status as a controlled substance, if scheduling is warranted. This commentary focuses on the approach and current issues related to...
Revista Brasileira de Psiquiatria
2026
Eduardo Aliende Perin, Nelson Carvas, Vinicius Tassoni Civile et al.
To evaluate the efficacy of mindfulness-based interventions for adults with obsessivecompulsive disorder. A systematic review and meta-analysis were conducted according to Cochrane Handbook guidelines. Two independent reviewers selected randomized controlled trials (RCTs) comparing mindfulness-based interventions with active control interventions, including cognitive/behavioral techniques and...
Heart & Lung
2026
Tania T Von Visger, Yu-Ping Chang
Adults with pulmonary hypertension (PH) live with a high symptom burden, psychological distress, and poor quality of life. Mindfulness-based interventions delivered in person or virtually have shown clinical benefits for chronic conditions and PH. Pilot testing of the Mindfulness Meditation for Pulmonary Hypertension (MMPH), an 8-week, web-based, multimodal program, shows improvement in...