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Depression: all studies

Page 522 of 1,034: studies 5,211 to 5,220 of 10,336, newest first. Back to the depression overview

Research

Meditation and spiritual practices in mental health: A comprehensive literature review

International Journal of Applied Research 2026 U Vijayabanu, Aswathi Bimal

Meditation and spiritual practices have moved from the margins of medical interest into the center of contemporary mental health research, with a rapidly growing body of randomized trials, neuroimaging studies, and systematic reviews. Evidence from programs such as Mindfulness Based Stress Reduction, yoga based interventions, Transcendental Meditation, loving kindness practices, and mantra...

DOI: 10.22271/allresearch.2026.v12.i3sa.13665 (opens in new tab) Full text (opens in new tab) Anxiety Transcendental meditation Mental health Psychological intervention +10

Mental health outcomes and use of online mental health tools following a public health deployment of the mindfulness meditation app headspace.

Frontiers in Digital Health 2026 Judith Borghouts, Elizabeth V Eikey, Cinthia De Leon et al.

Digital mental health interventions (DMHIs), such as mindfulness-based apps, have become popular mental health resources and can be associated with benefits such as reducing stress, anxiety, and depression. However, there are limited data on the impact of DMHIs on improving mental health outside of controlled research settings, and what factors may facilitate or inhibit such potential impact....

Case Report: Integrating CBT, hypnosis-based consciousness activation techniques, and yoga-based postural training: a three-pillar approach used for migrant populations.

Frontiers in Psychiatry 2026 Agnieszka Suchocka Capuano

Modern psychotherapy increasingly integrates multimodal and process-based approaches designed to respond to the complexity of contemporary clinical presentations. This paper introduces a three-pillar psychotherapeutic model combining (1) a revised cognitive behavioral foundation, (2) consciousness activation techniques derived from hypnosis, and (3) yoga-inspired postural and interoceptive...

Managing Psychological Challenges in the Subacute ("Afterglow") Window of Psychedelic Drug Effects.

Current Topics in Behavioral Neurosciences 2026 Ricarda Evens, Abdo Uyar, Tomislav Majić

The subacute period following the use of classic psychedelics is often marked by an "afterglow" - a state characterized by elevated mood; enhanced psychological well-being; increased emotional openness toward self, others, and nature; and sometimes a heightened sense of clarity and existential meaning. From a neurobiological perspective, subacute psychedelic states have been associated with...

DOI: 10.1007/7854_2025_612 (opens in new tab) Full text (opens in new tab) Afterglow Challenging Integration Psychedelic +1

Abuse liability of dextromethorphan and its combinatory formulation dextromethorphan/bupropion: a pharmacologic perspective.

Expert Opinion on Drug Metabolism & Toxicology 2026 Yang Jing Zheng, Christine E. Dri, Sabrina Wong et al.

Dextromethorphan/Buproprion (DXM/BUP) has received breakthrough FDA approval in August 2022 as a rapid-acting antidepressant. DXM/BUP is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist and sigma-1 receptor agonist, with bupropion (BUP), a norepinephrine/dopamine reuptake inhibitor and cytochrome P450 2D6 (CYP2D6) inhibitor. As DXM/BUP moves closer to widespread clinical use for...

DOI: 10.1080/17425255.2025.2607017 (opens in new tab) Full text (opens in new tab) Abuse Cyp2d6 Antidepressant Dextromethorphan/bupropion +3

Psychedelic-Associated Depersonalization-Derealization Disorder.

Current Topics in Behavioral Neurosciences 2026 Matthias Michal

Depersonalization (DP) and Derealization (DR) refer to perceptual changes of "as-if-character" where the self (→DP) or the surroundings (→DR) are experienced as unreal. These symptoms are highly prevalent in individuals with mental disorders. If these symptoms persist most of the day for months, the diagnosis of depersonalization-derealization-disorder (DDD) is likely. DDD is a common disorder...

Imagery Rehearsal Therapy (IRT) is associated with reduced nightmare severity and depressive, anxiety and suicidal symptoms in adults with Major Depressive Episode.

International journal of clinical and health psychology : IJCHP 2026 Julia Maruani, Nathan Martins, Emmanuelle Clerici et al.

Nightmare Disorder characterized by recurrent dysphoric dreams is strongly associated with major depressive episodes (MDE) and suicidal risk. Imagery rehearsal therapy (IRT) is the standard treatment for nightmares, but its effectiveness in individuals with MDE remain understudied. This study evaluated whether IRT is associated with greater improvement in nightmare symptoms compared to sleep...

Abuse potential assessment of novel central nervous system active and psychedelic substances for controlled substances act scheduling recommendations.

Journal of Psychopharmacology 2026 Jack E Henningfield, Sandra D Comer, Matthew L Banks et al. 5 citations

Abuse potential assessment of drugs with central nervous system activity is a critical component of the development of new medications for regulatory filings for approval worldwide. These new drug applications typically include recommendations for scheduling status as a controlled substance, if scheduling is warranted. This commentary focuses on the approach and current issues related to...

Mindfulness for obsessive-compulsive disorder: a systematic review and meta-analysis.

Revista Brasileira de Psiquiatria 2026 Eduardo Aliende Perin, Nelson Carvas, Vinicius Tassoni Civile et al.

To evaluate the efficacy of mindfulness-based interventions for adults with obsessivecompulsive disorder. A systematic review and meta-analysis were conducted according to Cochrane Handbook guidelines. Two independent reviewers selected randomized controlled trials (RCTs) comparing mindfulness-based interventions with active control interventions, including cognitive/behavioral techniques and...

Mindfulness meditation for pulmonary hypertension program development: Acceptability and feasibility of technology-assisted complementary health intervention for symptom self-management.

Heart & Lung 2026 Tania T Von Visger, Yu-Ping Chang

Adults with pulmonary hypertension (PH) live with a high symptom burden, psychological distress, and poor quality of life. Mindfulness-based interventions delivered in person or virtually have shown clinical benefits for chronic conditions and PH. Pilot testing of the Mindfulness Meditation for Pulmonary Hypertension (MMPH), an 8-week, web-based, multimodal program, shows improvement in...