PURPOSE/BACKGROUND: Chronic insomnia causes malaise and is associated with depression, irritability, cognitive impairment, impaired alertness, and substance abuse. Individuals with posttraumatic stress disorder (PTSD) often have both inadequate and fragmented sleep, putting them at elevated risk for these consequences. Sleep abnormalities in patients with PTSD include frequent trauma-related...
A depressão é um transtorno mental prevalente e incapacitante sendo considerado um problema de saúde pública. É caracterizada por humor deprimido persistente, perda de interesse em atividades diárias, alterações cognitivas e somáticas e, frequentemente, acompanhada por fadiga, alterações no sono ou no apetite. Estima-se que cerca de 20–40% dos pacientes com transtorno depressivo maior não...
Posttraumatic stress disorder (PTSD) is a chronic and disabling condition and identifying beneficial therapies is timely and important. We aimed to estimate the efficacy of 3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) compared with control on clinical and functional outcomes in PTSD. A PRISMA-compliant search (PROSPEROCRD42022353261) up to August 14, 2025, covered nine databases...
Students with disabilities are a group that faces more complex and complex mental health issues. Discrimination and difficulties experienced by students with disabilities during the learning process give rise to unpleasant feelings, putting them at higher risk for depression, anxiety, and other mental health problems. Therefore, mindfulness therapy is necessary to improve the mental health of...
Introdução: Os transtornos psiquiátricos representam um importante desafio na saúde pública mundial, com impacto significativo na qualidade de vida, funcionalidade e mortalidade dos pacientes. Embora os psicofármacos tradicionais, como antidepressivos, antipsicóticos e estabilizadores de humor sejam amplamente utilizados, muitos indivíduos apresentam resposta insatisfatória, falha terapêutica...
Bloy et al. [1] provide an important and methodologically rigorous secondary analysis of the Ketamine for the reduction of Alcoholic Relapse (KARE) trial, examining whether acute psychoactive effects mediate the therapeutic impact of ketamine in alcohol use disorder (AUD). Their finding that dissociative and perceptual effects did not mediate abstinence outcomes is clinically relevant, and...
Psychedelic compounds such as psilocybin, Lysergic Acid Diethylamide (LSD), N,Ndimethyltryptamine (DMT), and 3,4-methylenedioxymethamphetamine (MDMA) are emerging as novel therapeutics for neuropsychiatric disorders, including depression, Post-Traumatic Stress Disorder (PTSD), and addiction. Acting primarily through serotonin 5-HT2A receptor agonism, they activate intracellular cascades...
Objective: Mindfulness-based interventions (MBI) support mental health. We evaluated the feasibility and acceptability of a 12-week MBI in adolescents with obesity and type 2 diabetes or prediabetes. Methods: This was an uncontrolled, pilot, feasibility and acceptability evaluation in youth aged 15-17 years with type 2 diabetes or prediabetes. The Learning to BREATHE (L2B) curriculum was...
The present research conducted an analysis of the effects of mindfulness on emotional resilience and well-being of high school students, addressing the importance of incorporating this technique in the classroom using a qualitative approach and a descriptive design. The information was collected in Google Scholar, PubMed and Scopus platforms and, after a filtering process, 20 key articles were...
Career transitions constitute one of the most psychologically demanding phases in the lives of young people. The shift from education to employment, preparation for competitive examinations, uncertainty regarding career choices, unemployment, workplace adaptation, and changing socio-economic expectations frequently expose youth to heightened levels of stress, anxiety, emotional exhaustion, and...