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Depression: all studies

Page 436 of 1,034: studies 4,351 to 4,360 of 10,336, newest first. Back to the depression overview

Research

Uso de psicodélicos no tratamento da depressão resistente: eficácia clínica e perspectivas terapêuticas

Revista JRG de Estudos Acadêmicos September 16, 2026 Monique Vieira de Moura, Heder Albuquerque Azevedo Rocha, Márcio José de Carvalho Lima et al.

A depressão resistente ao tratamento (DRT) representa uma condição de elevada carga clínica e funcional, usualmente definida pela resposta inadequada a pelo menos dois tratamentos antidepressivos adequados. O interesse por psicodélicos clássicos ressurgiu diante da possibilidade de efeitos antidepressivos rápidos após uma ou poucas administrações em contexto supervisionado. O objetivo desta...

Effectiveness of Mindfulness-Based Techniques in Alleviating Anxiety and Stress Among Patients with Psychiatric Conditions

Leadership Education Personality An Interdisciplinary Journal September 15, 2026 2Dr. Jitendra Chicholkar 1Rahul Tiwari

Mindfulness-based techniques have gained significant attention as complementary treatments for managing anxiety and stress in individuals with psychiatric conditions. This study explores the effectiveness of mindfulness-based interventions (MBIs) in alleviating these symptoms among patients with various psychiatric disorders, such as depression, bipolar disorder, and generalized anxiety...

Next-Generation Psychedelic Drug Development

ACS Chemical Neuroscience September 15, 2026 Lindsay P. Cameron, Matthew W. Johnson, Kevin S. Murnane et al.

Psychedelic medicine has gained rapid popularity for the treatment of a variety of neuropsychiatric disorders, including depression, anxiety, and post-traumatic stress disorder. As novel psychedelic analogues and treatment regimes emerge, increasing numbers of variables are being tested. Here, we review various approaches and considerations for novel psychedelic therapies, including the...

Exploring Mechanisms, Methods, and Measurement in Mindfulness Research: A Scoping Review of Community-Based Interventions

Mindfulness September 15, 2026 Diana C. Parra, Abel Regassa, Bethel Ataro et al.

Abstract Objectives Mindfulness-based interventions (MBIs) have increasingly been implemented outside clinical environments and within community settings such as schools, workplaces, community health programs, and digital platforms. While the effectiveness of MBIs for improving psychological well-being is well established, less is known about the processes through which community-based...

Insecure Attachment, Mindfulness, and Resilience Among Adolescents: A Moderating Mechanism Review

Journal of language, culture and education. September 14, 2026 Suyu Zhu

Many teenagers today struggle with mental health issues: anxiety, depression, emotional dysregulation, relationship difficulties, and school‑related stress are common. A key underlying cause is insecure attachment. When teens are insecurely attached, they tend to have low resilience and more emotional problems. Resilience is a protective factor for mental health. It is the dynamic ability to...

Recalibrating Pain–Mood Coupling in Fibromyalgia: A Hypothesis-Generating Multisystem Neurobehavioral Framework for Mindfulness-Based Interventions

Anesthesia Research September 13, 2026 Camilla Teixeira Pinheiro Gusmão, Batuhan Özen, Marina Seixas Studart E Neves et al.

Background/Objectives: Fibromyalgia (FM) is a nociplastic pain syndrome characterized by chronic widespread pain, fatigue, sleep disturbance, cognitive dysfunction, and heightened sensitivity to somatic and environmental stimuli. Depressive symptoms and major depressive disorder (MDD) frequently co-occur with FM and are associated with greater disability, pain catastrophizing, sleep disruption,...

Moderators of the Effects of Telehealth Mindfulness-based Interventions for Chronic Pain

Clinical Journal of Pain September 10, 2026 Colin Calvert, Emily M Hagel Campbell, Lee J. S. Cross et al.

OBJECTIVES: Little is known about who benefits most from Mindfulness-Based Interventions (MBIs), and whether certain groups differentially benefit from different types of MBI formats (group-based versus non-group based). The present study uses data from a three-arm randomized controlled trial (ClinicalTials.gov ID: NCT04526158) of two MBIs (self-paced and group) to test moderating effects by...

Influence of pranic healing and mindfulness on respiratory function, physical endurance, and well-being: A randomized single-blind study among paramedical students

Health Psychology Research September 10, 2026 Vinu Vijayakumar, Mahesh Pudukudru Anand, Srikanth N. Jois et al.

Background: In pranic healing, a naturopathic biofield (prana) therapy, wellness is achieved by balancing life energy, also known as prana. Studies confirm its effectiveness in lowering rates of depression and anxiety, along with improving sleep quality and functional health. Objective: To evaluate the effects of mass pranic healing (MPH) on lung function and physical performance among...

Prior ayahuasca experience is associated with improved mental health: observational data from ritualistic settings

npj Mental Health Research September 10, 2026 Lucas Cruz, Marcio S. C. Longo, Rafael S. Rodrigues et al.

Abstract This observational survey study investigated the relationship between prior ayahuasca experience and mental health and mindset outcomes. Participants planning to attend an ayahuasca ceremony completed a survey before their upcoming ayahuasca use. Measures included substance use, depression, anxiety, stress, spiritual well-being, aberrant salience, and metaphysical beliefs. Participants...

457. Intensive longitudinal monitoring of symptoms in response to treatment with intranasal esketamine

The International Journal of Neuropsychopharmacology September 9, 2026 M Saje, Jurij Bon, Aleš Oblak

Abstract Background Esketamine is a NMDA receptor antagonist that has been approved as treatment for treatment-resistant depression (TRD). Unlike serotoninergic therapies requiring weeks for effect, intranasal esketamine modulates glutamate neurotransmission, often yielding symptom relief within hours and significant response rates within one month [1]. This rapid action is particularly...