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Depression: all studies

Page 430 of 1,034: studies 4,291 to 4,300 of 10,336, newest first. Back to the depression overview

Research

The New Mexico Medical Psilocybin Act and current trends in the United States psychedelic policy

Psychedelics October 1, 2026 Diego Borbón

In April 2025, New Mexico enacted the Medical Psilocybin Act, establishing the first legislated statewide medical psilocybin program and becoming the third state to authorize supervised psilocybin use. The Act directs the New Mexico Department of Health to build a regulated system where licensed clinicians provide psilocybin to qualified patients in approved settings for treatment-resistant...

Study Participant Perceptions of the Relevance of Therapist and Study Team Personal Psychedelic Experience

Psychedelics October 1, 2026 Benjamin R. Lewis, Eric L Garland, Zach Schwartz et al.

Background Psychedelic-assisted psychotherapy (PAP) has demonstrated great promise for a variety of mental health problems. Many clinicians and researchers who are engaged in providing PAP report personal experiences with psychedelics; these experiences are often positive. Still, there are ongoing questions regarding the relevance of therapists personal experience with psychedelic drugs for the...

The Consciousness Exemption Problem

Zenodo (CERN European Organization for Nuclear Research) October 1, 2026 ROY Partha Partha preprint

Whether current or near-future artificial intelligence systems possess phenomenal consciousness or sentience remains scientifically and philosophically unresolved, a fact openly acknowledged even by the industry laboratories that build these systems. This paper argues that this very uncertainty, far from licensing reduced ethical scrutiny, obligates greater scrutiny of AI systems deployed to...

Ketamine in psychiatry: a systematic review of clinical applications, safety considerations, and emerging challenges

Frontiers in Psychiatry October 1, 2026 Matthew M. Kinney, Zackary L. Bowers

Ketamine has progressed from solely being an anesthetic agent to a drug of rising clinical and research interest due to its distinctive pharmacological properties. Its dissociative properties and rapid-acting antidepressant effects have made it a prominent area of investigation across many medical and psychiatric applications. This systematic review examines ketamine’s history, mechanisms of...

Impacts of digital third-wave interventions for adults on wellbeing and mental health outcomes: A systematic review and meta-analysis of randomized controlled trials.

PLOS digital health October 2026 Tom C Gordon, Andrew H Kemp, Josh Hope-Bell et al.

To synthesise the efficacy of digital third-wave process-based interventions (e.g., ACT, Mindfulness, Compassion) for improving wellbeing and ameliorating mental health symptoms in adults. A prospectively registered systematic review (OSF: 10.17605/OSF.IO/5RMU2) and random-effects meta-analysis of randomised controlled trials (RCTs) was conducted across six databases through January 2026....

Effects of Cognitive Behavioral Couple Therapy With Integrated Mindfulness on Mindful Attention, Depressive Symptoms, and Dyadic Adjustment in Low‐Income Couples: A Pilot Randomized Clinical Trial

Journal of Marital and Family Therapy October 1, 2026 Ricardo S. S. Durães, Zila Elizabeth Pulache Vargas, Ana Cristina Garcia Dias et al.

ABSTRACT Psychosocial distress can exacerbate marital conflict, maladjustment, and mental health vulnerability. This pilot randomized clinical trial examined cognitive‐behavioral couple therapy (CBCT) integrated with mindfulness in low‐income Brazilian couples (per‐capita household income up to one minimum wage). Thirty‐four participants (17 heterosexual couples) were randomized (independent...

Cognitive-Affective Factors Associated with Psychological Distress in Young Adults: A Cross-Sectional Structural Equation Modelling Study

PsyArXiv Preprints September 30, 2026 preprint

Objectives: To examine concurrent associations among cognitive-affective factors associated with psychological distress in young adults. Methods: Cross-sectional structural equation modelling was conducted in a community sample of 841 young adults aged 18 to 30 years. Psychological distress was specified as a latent factor indicated by depressive symptoms (PHQ-9), anxious symptoms (GAD-7), and...

Therapeutic Efficacy of Rajayoga Meditation and Varma Therapy in Attenuating Occupational Stress and Reversing Non-Alcoholic Fatty Liver Disease among Night-Shift Information Technology Professionals

International Journal of Academic Excellence and Research September 30, 2026 S Venkatesan, D Rajendran

The growing incidence of Non-Alcoholic Fatty Liver Disease (NAFLD) among night-shift IT professionals is posing as a major occupational health issue since shift work, sedentary lifestyle, psychosocial stress, lack of sleep, and disrupted circadian rhythms can lead to metabolism problems and fatty liver. Even though there is a possibility to cure NAFLD by adopting lifestyle changes, the...

PHYSIOLOGY OF MEDITATION WITH REFERENCE TO VARIOUS MANASIKA VYADHI

Intemed International Journal of Research in Integrated Medical Sciences September 30, 2026 Suhas More, Pankaj Kakde, Namita Gaikwad

Mental health and psychosomatic disorders are increasingly recognized as important contributors to morbidity and impaired quality of life. Anxiety, depressive symptoms, chronic stress, sleep disturbances and stress- related somatic complaints are associated with alterations in emotional regulation, autonomic function, neuroendocrine activity and cognitive processing. Ayurveda gives considerable...

Psychological and neuropsychological effects of adolescent cannabis use: a structured narrative review.

Journal of Addictive Diseases September 30, 2026 Rocco Miazzi, Clara Cestonaro, Claudio Terranova

BACKGROUND Adolescence represents a vulnerable developmental period during which cannabis exposure may be associated with psychological, neuropsychological, and neurobiological alterations. OBJECTIVE This structured review examines the psychological and neuropsychological effects associated with cannabis use during adolescence, focusing exclusively on human studies. METHODS A structured...