Clinical Journal of Pain
September 10, 2026
Colin Calvert, Emily M Hagel Campbell, Lee J. S. Cross et al.
OBJECTIVES: Little is known about who benefits most from Mindfulness-Based Interventions (MBIs), and whether certain groups differentially benefit from different types of MBI formats (group-based versus non-group based). The present study uses data from a three-arm randomized controlled trial (ClinicalTials.gov ID: NCT04526158) of two MBIs (self-paced and group) to test moderating effects by...
Clinical Journal of Pain
July 1, 2026
Michael Yufeng Wang, M Prabhavi N Perera, Paul B. Fitzgerald et al.
Objective: Mindfulness-based interventions (MBIs) show promise in managing chronic pain but often require substantial time commitments, leading to high attrition and concerns about acceptability. This meta-analysis evaluated attrition rates in MBIs for chronic pain and examined moderators contributing to participant withdrawal. Methods: Following PRISMA guidelines, we searched relevant...
Clinical Journal of Pain
April 1, 2026
Michelle A. Clementi, Michelle Harmon, Emily F. Law et al.
Objectives: Adolescents with chronic migraine face increased risk for comorbid anxiety and depression that, can hinder migraine self-management and coping. Mindfulness-based interventions may reduce anxiety/depression to improve migraine outcomes, yet require tailoring to increase acceptability and engagement among this distinct population. The current study used qualitative methods to explore...
Clinical Journal of Pain
November 1, 2025
Perianen Ramasawmy, Andrea Antal, Olga L Gamboa Arana et al.
Mindfulness-based interventions (MBIs) appear to improve emotion regulation (ER) in disorders involving emotional dysregulation like fibromyalgia (FM). Despite the therapeutic potential of transcranial direct current stimulation (tDCS) in FM, its concurrent application with mindfulness meditation (MM) has not yet been explored. Potential synergistic effects may arise from aligning neural...
Clinical Journal of Pain
February 1, 2024
Myrella Paschali, Asimina Lazaridou, Jason Sadora et al.
25 citations
This systematic review aimed to compile existing evidence examining the effects of mindfulness-based interventions (MBIs) for chronic low back pain (CLBP). CLBP leads to millions of disabled individuals in the United States each year. Current pharmacologic treatments are only modestly effective and may present long-term safety issues. MBIs, which have an excellent safety profile, have been...
Clinical Journal of Pain
August 1, 2023
Orla Deegan, Brona M Fullen, Maire Brid Casey et al.
Limited studies exist combining mindfulness-based stress reduction (MBSR) and exercise in a pain management programme (PMP), with none thus far delivering a combined intervention as an online PMP. This study aimed to explore the acceptability and feasibility of a combined MBSR and exercise online PMP for adults with chronic pain and to examine the feasibility of conducting a randomized...
Clinical Journal of Pain
October 1, 2020
Melissa A Day, L. Charles Ward, Beverly E Thorn et al.
Objectives: This study evaluated theoretically derived mechanisms and common therapeutic factors to test their role in accounting for pain-related outcome change during group-delivered cognitive therapy, mindfulness meditation, and mindfulness-based cognitive therapy for chronic low back pain. Methods: A secondary analysis of a pilot randomized controlled trial was used to explore the primary...
Clinical Journal of Pain
July 1, 2018
Biyanka Komandur, Paul R. Martin, Siavash Bandarian-Balooch
Objectives: To replicate a study by Schutze and colleagues on a headache sample, rather than a heterogenous chronic pain sample, investigating whether level of mindfulness predicts key components in the Fear-Avoidance Model of chronic pain (pain intensity, negative affect, pain catastrophizing, pain-related fear, pain hypervigilance, and functional disability); to investigate the relationships...
Clinical Journal of Pain
January 2018
Maja Johannsen, Maja O'Connor, Mia S O'Toole et al.
The aim of this study was to investigate possible statistical mediators in a randomized controlled trial of mindfulness-based cognitive therapy (MBCT) on pain intensity in women treated for primary breast cancer. The sample consisted of 129 women treated for breast cancer, presenting with persistent pain, who were randomly assigned to MBCT or a wait-list control. We previously reported a...
Clinical Journal of Pain
November 1, 2017
Danielle A. Ruskin, Michelle M. Gagnon, Sara A. Kohut et al.
Objectives: Pediatric chronic pain is a major health issue that can lead to significant interference in daily functioning. Mindfulness-based interventions (MBI’s), which emphasize acceptance rather than control of pain, have gained increasing attention as a viable treatment option among adults with chronic pain. The effectiveness of MBIs for chronic pain in pediatric populations remains largely...
Clinical Journal of Pain
May 2017
Paul Grossman, Gunnar Deuring, Harald Walach et al.
Fibromyalgia (FM) is a syndrome characterized by severe pain, fatigue and sleep disturbance. There is evidence of central hyper-responsiveness to sensory stimulation and impaired cardiovascular autonomic control. Laboratory investigations suggest that mindfulness-based stress reduction (MBSR) may improve autonomic functioning in FM. However, these findings may not reflect what occurs during...
Clinical Journal of Pain
February 1, 2017
Elizabeth A. Thomas, Eric L Garland
Objectives: Chronic pain and long-term opioid use may lead to a persistent deficit in hedonic capacity, characterized by increased sensitivity to aversive states and insensitivity to natural rewards. Dispositional mindfulness has been linked with improved emotion regulation and pain coping. The aim of the current study was to examine associations between dispositional mindfulness, hedonic...
Clinical Journal of Pain
May 2016
Melissa A Day, James Halpin, Beverly E Thorn
It is often assumed that psychosocial pain treatments work because of specific active components of the intervention. The degree to which common factors may contribute to improved pain outcomes is not well researched. The purpose of this study was to examine patient-related and therapist-related common factors during a Mindfulness-Based Cognitive Therapy (MBCT) for headache pain trial. This...
Clinical Journal of Pain
June 2014
Mohammed A Issa, Sanjeet Narang, Robert N. Jamison et al.
Many cannabinoid medications are approved in North America or in phase III trials, such as dronabinol, nabilone, or nabiximols. Little is known about their subjective psychoactive effects when used for pain management. We hypothesized that when used for pain, dronabinol has psychoactive effects in a dose-response relationship, whose peak effects are comparable with smoking marijuana. This was a...
Clinical Journal of Pain
June 1, 2014
A-Mm Williams, A. Caño
Objectives:Existing research has reported the correlation between patients’ psychological flexibility, of which mindfulness is a component, and their perceptions of the spouses’ support provision. It is quite likely that spouses’ mindfulness, in particular certain aspects of mindfulness, is also related to the support they provide to patients. The current study examined this issue. Materials...
Clinical Journal of Pain
October 2011
Samuel Yeung Shan Wong, Frank Wan-Kin Chan, Rebecca Lai-Ping Wong et al.
Research suggests that an 8-week Mindfulness-Based Stress Reduction (MBSR) program (a structured form of meditation) might be effective in the treatment of various health problems including chronic pain. Our objective was to compare the clinical effectiveness of the MBSR program with a multidisciplinary pain intervention (MPI) program in terms of pain intensity, pain-related distress, quality...
Clinical Journal of Pain
1986
Jon Kabat‐zinn, Leslie Lipworth, R. Burncy et al.
485 citations
Two hundred twenty-five chronic pain patients were studied following training in mindfulness meditation. Large and significant overall improvements were recorded post-intervention in physical and psychological status. These gains were maintained at follow-up in the majority of subjects. Follow-up times ranged from 2.5–48 months. Status on the McUill Melzack Fain Rating Index (PRI). however,...