Experimental and Clinical Psychopharmacology
September 27, 2018
Anne Baker, Eric L Garland
Prescription opioid misuse among chronic pain patients is undergirded by self-regulatory deficits, affective distress, and opioid-cue reactivity. Dispositional mindfulness has been associated with enhanced self-regulation, lower distress, and adaptive autonomic responses following drug-cue exposure. We hypothesized that dispositional mindfulness might serve as a protective factor among...
JMIR Mental Health
September 25, 2018
Julia Sevilla-Llewellyn-Jones, Olga Santesteban-Echarri, Ingrid Pryor et al.
Web-based mindfulness interventions are increasingly delivered through the internet to treat mental health conditions. The objective of this study was to determine the effectiveness of web-based mindfulness interventions in clinical mental health populations. Secondary aims were to explore the impact of study variables on the effectiveness of web-based mindfulness interventions. We performed a...
Journal of experimental neuroscience
September 19, 2018
David E. Olson
Neural plasticity-the ability to change and adapt in response to stimuli-is an essential aspect of healthy brain function and, in principle, can be harnessed to promote recovery from a wide variety of brain disorders. Many neuropsychiatric diseases including mood, anxiety, and substance use disorders arise from an inability to weaken and/or strengthen pathologic and beneficial circuits,...
Neuropsychopharmacology
September 6, 2018
Haley L Goodwill, Gabriela Manzano-Nieves, Meghan Gallo et al.
Childhood trauma and neglect influence emotional development and increase the risk for and severity of mental illness. Women have a heightened susceptibility to the effects of early life stress (ELS) and are twice as likely as men to develop debilitating, stress-associated disorders later in life, such as major depressive disorder (MDD). Until now, mouse models of depression have been largely...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
August 30, 2018
Manoj P Dandekar, Tao Peng, David D McPherson et al.
Similar to ketamine, xenon gas acts as a glutamatergic N-methyl-d-aspartate receptor antagonist, but devoid of propensity to cause untoward effects. Herein, we loaded xenon gas into a liposomal carrier called xenon-containing liposomes (Xe-liposome) for systemic delivery, and investigated its effect as an antidepressant and also analyzed synaptic biomarkers including brain-derived neurotrophic...
Journal of Affective Disorders
August 1, 2018
Carrie Cuttler, Alexander Spradlin, Ryan J Mclaughlin
Cannabis is commonly used to alleviate symptoms of negative affect. However, a paucity of research has examined the acute effects of cannabis on negative affect in everyday life. The current study provides a naturalistic account of perceived changes in symptoms of depression, anxiety, and stress as a function of dose and concentration of Δ9tetrahydrocannabinol (THC) and cannabidiol (CBD). Data...
Psychiatry Research
August 2018
Xiaoyin Ke, Yi Ding, Ke Xu et al.
The aim of this study was to examine the cognitive function in chronic ketamine users. Factors correlated to cognition impairments were analyzed. Sixty-three chronic ketamine users and 65 healthy subjects were recruited. Cognitive function was assessed by using immediate/delayed visual reproduction (IVR/DVR) tasks, immediate/delayed logical memory (ILM/DLM) tasks, Stroop test, Wisconsin card...
Asian Pacific journal of cancer prevention : APJCP
July 27, 2018
Somye Pouy, Fatemeh Attari Peikani, Hassan Nourmohammadi et al.
Cancer poses substantial challenges to both physical and mental health of patients. On the other hand, breast cancer is one of the most common cancers among Iranian women. Therefore, the present study was conducted to investigate the effect of mindfulness-based training on psychological status and quality of life (QoL) of patients with breast cancer living in Ilam, Iran. This quasi-experimental...
Psychological Assessment
July 26, 2018
Jason M Prenoveau, Alison A Papadakis, Jacob C S Schmitz et al.
No study has yet assessed the psychometric properties of scores from any mindfulness measure in racial minority adolescents from low-income environments. The present study examined the reliability and validity of Child and Adolescent Mindfulness Measure (CAMM) scores in a nonclinical sample of late adolescents (N = 92) from low-income neighborhoods who predominantly identified as African...
Journal of Complementary and Integrative Medicine
July 19, 2018
Mathew P Varghese, Ragavendrasamy Balakrishnan, Subramanya Pailoor
Background Type 2 diabetes mellitus [T2DM] is one of the leading causes for mortality. This study examined the role of an self-awareness based guided meditation practice, Cyclic Meditation [CM] on perceived stress, anxiety, depression, sleep and quality of life in T2DM patients. Design A single arm pre-post design was used for the study. Setting The study was conducted in an auditorium for...