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Depression: all studies

Page 403 of 1,034: studies 4,021 to 4,030 of 10,336, newest first. Back to the depression overview

Research

Hypnotherapy or transcendental meditation versus progressive muscle relaxation exercises in the treatment of children with primary headaches: a multi-centre, pragmatic, randomised clinical study.

European Journal of Pediatrics October 24, 2018 M C Jong, I Boers, H A Van Wietmarschen et al.

Many children suffer from headaches. Since stress may trigger headaches, effective techniques to cope with stress are needed. We investigated the effectiveness of two mind-body techniques, transcendental meditation (TM) or hypnotherapy (HT), and compared them with progressive muscle relaxation (PMR) exercises (active control group). Children (9-18 years) suffering from primary headaches more...

Mindfulness-based program for stress reduction in infertile women: Randomized controlled trial.

Stress and Health October 16, 2018 Simone F Nery, Sara P C Paiva, Érica L Vieira et al.

Infertile women often experience chronic stress, which may have a negative impact on general well-being and may increase the burden of infertility. In this open-label, parallel, randomized controlled trial, infertile women aged 18-50 years (median 37 years) were assigned to an 8-week mindfulness-based program (MBP) or no intervention. The primary outcome was stress severity measured by the...

Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents.

Molecules October 11, 2018 Bronwyn M Kivell, Kelly F Paton, Nitin Kumar et al. 45 citations

The acute activation of kappa opioid receptors (KOPr) produces antinociceptive and anti-cocaine effects, however, their side-effects have limited further clinical development. Mesyl Sal B is a potent and selective KOPr analogue of Salvinorin A (Sal A), a psychoactive natural product isolated from the plant Salvia divinorum. We assessed the antinociceptive, anti-cocaine, and side-effects of...

Relationship Between Mindfulness and Posttraumatic Stress in Women Who Experienced Stillbirth.

Journal of Obstetric, Gynecologic, and Neonatal Nursing October 5, 2018 Jennifer Huberty, Jeni Green, Joanne Cacciatore et al.

Objective: To explore the potential factors that mediate the relationship between mindfulness and symptoms of posttraumatic stress (PTS) in women who experienced stillbirth. Design: A cross-sectional analysis of baseline data before women's participation in an online mindfulness intervention (i.e., online yoga). Setting: This was a national study, and women participated in their own homes....

An evaluation of a low intensity mHealth enhanced mindfulness intervention for Chinese university students: A randomized controlled trial.

Psychiatry Research October 2, 2018 Brian J Hall, Peng Xiong, Xinqi Guo et al.

Mental disorders and sleep dysfunction are common among Chinese university students. This study aimed to evaluate a low cost scalable mindfulness intervention program to improve psychological health and sleep quality among Chinese university students. A randomized controlled trial with 101 university students (mean age 22.30 ± 2.63, 69.31% female) was conducted. Participants were randomized...

The Role of Mindfulness in the Insomnia Severity of Female Chronic Hypnotic Users.

International Journal of Behavioral Medicine October 1, 2018 Daniela Curado, Viviam Barros, Emerita Opaleye et al.

Purpose: To investigate dispositional mindfulness, psychiatric symptoms, and their relationship with insomnia severity among female chronic hypnotic users. Methods: Observational, cross-sectional study, including 76 women with chronic hypnotic use. Participants completed several self-report questionnaires: sociodemographic characteristics, depressive symptoms (CES-D), anxiety levels (STAI-T),...

Mindfulness-Based Versus Health Promotion Group Therapy After Traumatic Brain Injury.

Journal of Psychosocial Nursing and Mental Health Services October 1, 2018 Esther Bay, Roxane Raffin Chan

The current pre- and posttest intervention study is designed for individuals with chronic symptoms and stress associated with mild-to-moderate traumatic brain injury (TBI). The researchers' intent was to evaluate whether an 8-week mindfulness-based group therapy compared to health promotion active control group therapy reduces chronic stress, TBI symptoms, and depressive symptoms. Significant...

The effect of route of administration on the enantioselective pharmacokinetics of ketamine and norketamine in rats.

Journal of Psychopharmacology October 2018 Martin Le Nedelec, Paul Glue, Helen Winter et al.

Ketamine has been shown to produce a rapid and potent antidepressant response in patients with treatment-resistant depression. Currently ketamine is most commonly administered as a 40-minute intravenous infusion, though it is unknown whether this is the optimal route of administration. To determine the plasma concentration time course of the R- and S-enantiomers of ketamine and norketamine...

The role of glutamatergic modulation in the mechanism of action of ketamine, a prototype rapid-acting antidepressant drug.

Pharmacological Reports October 2018 Agnieszka Pałucha-Poniewiera

Over the past decade, ketamine has been one of the most commonly studied potential antidepressants. This is because it produces a spectacularly rapid and persistent therapeutic effect in people suffering from severe treatment-resistant depression (TRD), for which classical drugs are ineffective. Similar efficacy was demonstrated for scopolamine, a drug belonging to a completely different...

A randomized, controlled trial of mindfulness-based stress reduction in HIV infection.

Brain, Behavior, and Immunity October 2018 Frederick M Hecht, Judith T. Moskowitz, Patricia J Moran et al.

Evidence links depression and stress to more rapid progression of HIV-1 disease. We conducted a randomized controlled trial to test whether an intervention aimed at improving stress management and emotion regulation, mindfulness-based stress reduction (MBSR), would improve immunological (i.e. CD4+ T-cell counts) and psychological outcomes in persons with HIV-1 infection. We randomly assigned...