International journal of mental health systems
October 13, 2023
Giovana Gonçalves Gallo, Daniela Fernandez Curado, Mayra Pires Alves Machado et al.
18 citations
The development of mental health disorders is common in the university population, and mindfulness-based interventions (MBIs) seem to be effective in addressing them in different contexts. Thus, this study investigated the impact of an 8-week MBI adapted to university students from the Mindfulness-Based Relapse Prevention (MBSR) on different symptoms related to mental health problems,...
Biological Psychiatry Global Open Science
October 1, 2023
Ben Julian A Palanca, Charles R Conway, Thomas Zeffiro et al.
Nitrous oxide holds promise in the treatment of major depressive disorder. Its psychotropic effects and NMDA receptor antagonism have led to comparisons with ketamine. Despite longstanding use, persistent effects of nitrous oxide on the brain have not been characterized. Sixteen healthy volunteers were recruited in a double-blind crossover study. In randomized order, individuals underwent a...
Archives of Razi Institute
October 1, 2023
Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth et al.
Since depression is a common mental illness affecting an estimated 5% of people worldwide, investigators are encouraged to develop effective antidepressants. According to the monoamine-deficiency hypothesis, the underlying pathophysiology of depression is a deficiency of some neurotransmitters (serotonin, norepinephrine, or dopamine) in the central nervous system. The neurotransmitter serotonin...
JMIR Research Protocols
September 22, 2023
Diane Elliot, Kerry Kuehl, Carol DeFrancesco et al.
Background: Correction professionals are a highly stressed workforce with heightened risks for depression, suicide, obesity, cardiovascular disease, and injury. These professionals, largely hidden from view, have received little study concerning means to improve their safety, health, and well-being. In other settings, mindfulness has resulted in lowered stress, along with other benefits. We...
European Journal of Pharmacology
September 15, 2023
Barbara G Ferri, Cintia O De Novais, Raquel S Bonani et al.
11 citations
Ring-substituted phenethylamines are believed to induce psychedelic effects primarily by interacting with 5-hydroxytryptamine 2 (5-HT2A) receptors in the brain. We assessed the effect of the psychedelic substances 25H-NBOMe and 25H-NBOH on the depressive-like behavior of male adult rats. Naive Wistar rats were divided into groups to assess the effects of different doses (0.1 mg/kg, 1 mg/kg, and...
European Journal of Investigation in Health, Psychology and Education
September 1, 2023
Monique L Mefrouche, Eva-Maria Siegmann, Stephanie Böhme et al.
15 citations
Introduction. Pregnancy is a unique time in a woman's life that can be both exciting and challenging. It is also a period that can be associated with significant stress, anxiety, and depression, which can have negative consequences for both the mother and the baby. Mindfulness interventions are known to be a well-suited treatment and prevention method for psychiatric symptoms in pregnancy, and...
Pharmacology, Biochemistry, and Behavior
September 1, 2023
Yixue Qin, Haoxuan Li, Yuqi Zhang et al.
6 citations
Ketamine has been increasingly used as a rapid-onset antidepressant in specific clinical settings. However, as a psychedelic reagent, the potential of physical and psychological dependence limits its clinical use. Here, we added retigabine, a KCNQ channel opener, as an adjunctive treatment to observe its effect on ketamine's antidepressant property in a forced swim test in both male and female...
Mindfulness
September 1, 2023
Blair T Johnson, Rebecca L. Acabchuk, Elisabeth A George et al.
45 citations
Universities increasingly offer mindfulness-based programs (MBPs) to improve student health and reduce their impact on overburdened psychological services. It is critical for evidence-based policy to determine for what health outcomes mindfulness programs are effective and under what conditions. Objectives were to: (a) perform a comprehensive analysis of the effects of mindfulness interventions...
Psychiatry and Clinical Neurosciences Reports
September 1, 2023
Chisato Tanaka, Kenta Wakaizumi, Akira Ninomiya et al.
3 citations
The coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented stress. Mindfulness-based interventions (MBIs) are known to be effective in reducing stress. However, it is unclear how long-term outcomes differ between those who continue mindfulness practice after MBIs and those who do not. In this study, we hypothesized that those who continued mindfulness practice would have higher...
Journal of Pain and Symptom Management
September 1, 2023
Benjamin R. Lewis, Eric L Garland, Kevin Byrne et al.
60 citations
Psilocybin-assisted psychotherapy shows promise in treating depression and existential distress in people with serious medical illness. However, its individual-based methodology poses challenges for scaling and resource availability. The HOPE trial (A Pilot Study of Psilocybin Enhanced Group Psychotherapy in Patients with Cancer) is an Institutional Review Boards-approved open-label feasibility...