Depression: all studies (page 370) - The Consciousness Library

The mental health of nursing students during the COVID-19 pandemic: Beneficial effects of mindfulness-based stress reduction.

Heliyon June 30, 2024 Fariba Eslamimoghadam, Zahra Abedini, Ashraf Khoramirad 7 citations

Following the COVID-19 global emergency, health students were faced with increased workloads, university closures, study interruptions, loss of peer support networks, and the challenges of volunteer work in hospitals. These factors caused health students to experience significant stress and anxiety, highlighting the necessity of psychological interventions for this group. Several studies have...

DOI: 10.1016/j.heliyon.2024.e32986 Full text Anxiety Depression Mindfulness-based stress reduction Nursing students

Study protocol for the MIND-PD study: a randomized controlled trial to investigate clinical and biological effects of mindfulness-based cognitive therapy in people with Parkinson's disease.

BMC Neurology June 25, 2024 Anouk Van der Heide, Franziska Goltz, Nienke M De Vries et al. 5 citations

People with Parkinson's disease (PD) are very sensitive to the effects of stress. The prevalence of stress-related neuropsychiatric symptoms is high, and acute stress worsens motor symptoms. Animal studies suggest that chronic stress may accelerate disease progression, but evidence for this in humans is lacking. Mindfulness-based interventions (MBIs) train participants to focus on the present...

DOI: 10.1186/s12883-024-03736-7 Full text Anxiety Depression Disease progression Mindfulness-based cognitive therapy +2

Treatment and therapy of mental health conditions in the Global South using psychedelics: A scoping review and narrative synthesis

Journal of Psychedelic Studies June 21, 2024 Caroline Griffin, Alec Knight 3 citations

AbstractBackground and aimsPsychedelics show promise for treatment of mental health conditions (MHCs). But there is relatively little research on indigenous psychedelics conducted in the Global South (GS). Much research is carried out in the Global North, where there are different cultural perceptions of mental health and psychedelics. Therefore, this paper appraises research on psychedelics...

DOI: 10.1556/2054.2024.00333 Depression Psychedelic therapy Mental health conditions Unmet needs +6

The association between ketamine and esketamine and suicidality: reports to the Food And Drug Administration Adverse Event Reporting System (FAERS).

Expert Opinion on Drug Safety June 21, 2024 Roger S McIntyre, Rodrigo B. Mansur, Joshua D. Rosenblat et al. 7 citations

Replicated evidence indicates that ketamine and esketamine reduce measures of suicidality in persons with treatment-resistant depression (TRD). It remains uncertain whether individuals experience worsening of preexisting suicidality with either agent. The Food and Drug Administration Adverse Event Reporting System (FAERS) database was searched from 1970 and 2019 to 30 September 2023 for reports...

DOI: 10.1080/14740338.2024.2368827 Full text Esketamine Treatment-resistant depression Suicidality Depression treatment +3

Mindfulness-based interventions for improving mental health of frontline healthcare professionals during the COVID-19 pandemic: a systematic review.

Systematic Reviews June 20, 2024 Gemma Benavides-Gil, Fermín Martínez-zaragoza, Jordi Fernández-castro et al. 22 citations

Mindfulness-based interventions (MBIs) appear to be effective for improving the mental health of healthcare professionals (HCPs). However, the effectiveness of MBIs on extreme psychological trauma caused by the coronavirus disease 2019 (COVID-19) pandemic is largely unknown. The aim of this paper was to systematically review empirical studies of MBIs for HCPs carried out during the COVID-19...

DOI: 10.1186/s13643-024-02574-5 Full text Anxiety Depression Burnout Covid-19 +5

(R)-(-)-Ketamine: The Promise of a Novel Treatment for Psychiatric and Neurological Disorders.

International Journal of Molecular Sciences June 20, 2024 Hana Shafique, Julie C Demers, Julia Biesiada et al. 29 citations

NMDA receptor antagonists have potential for therapeutics in neurological and psychiatric diseases, including neurodegenerative diseases, epilepsy, traumatic brain injury, substance abuse disorder (SUD), and major depressive disorder (MDD). (S)-ketamine was the first of a novel class of antidepressants, rapid-acting antidepressants, to be approved for medical use. The stereoisomer, (R)-ketamine...

DOI: 10.3390/ijms25126804 Full text R-ketamine Major depressive disorder Substance use disorder Inflammation +5

The cyclical revival of psychedelics in psychiatric treatment

Current Medical Research and Opinion June 17, 2024 Francisco J Appiani, Stanley N. Caroff 5 citations

There is an increasing demand for effective treatments for depression, particularly for individuals grappling with treatment-resistant depression. Over recent years, a surge of interest has focused on exploring the safety and efficacy of psilocybin as a potential treatment for depression. However, preliminary findings from phase 2 studies have been inconclusive, prompting critical examination...

DOI: 10.1080/03007995.2024.2368725 Depressive disorder Psilocybin Hallucinogenic therapy Hallucinogens +5

Time-dependent antidepressant-like effects of reelin and ketamine in the repeated-corticosterone model of chronic stress.

Progress in Neuro-Psychopharmacology and Biological Psychiatry June 8, 2024 Kaylene K A Scheil, Carla L Sánchez-Lafuente, Brady S Reive et al. 5 citations

There is an urgent need for novel antidepressants, given that approximately 30% of those diagnosed with depression do not respond adequately to first-line treatment. Additionally, monoaminergic-based antidepressants have a substantial therapeutic time-lag, often taking months to reach full therapeutic effect. Ketamine, an N-methyl-d-aspartate receptor (NMDAR) antagonist is the only current...

DOI: 10.1016/j.pnpbp.2024.110998 Full text Ketamine Chronic stress Corticosterone Rapid-acting antidepressants +5

10-Week Trajectories of Candidate Psychological Processes Differentially Predict Mental Health Gains from Online Dyadic versus Mindfulness Interventions: A Randomized Clinical Trial.

Journal of Clinical Medicine June 3, 2024 Malvika Godara, Tania Singer 5 citations

Background: App-based contemplative interventions, such as mindfulness-based interventions, have gained popularity for the promotion of mental health; however, the understanding of underlying intervention-specific mechanisms remains limited, especially related to novel inter-relational dyadic practices. Methods: We tested (n = 253) seven putative mechanisms underlying two brief (daily 12-min)...

DOI: 10.3390/jcm13113295 Full text Anxiety Depression Mindfulness Acceptance +4

The effect of 20-minute mindful breathing exercise on psychological well-being in epilepsy: A pilot randomized controlled trial.

Epilepsy & Behavior June 1, 2024 Kheng-Seang Lim, Si-Lei Fong, Xuen Yu et al. 6 citations

Depression and anxiety are prevalent in epilepsy patients, but psychiatric or psychological services may not be accessible to all patients. This study aimed to determine the effectiveness of the 20-minute mindful breathing on the psychological well-being of PWE using an instructional video. This was a pilot, assessor-blinded, randomized controlled trial. The intervention group received a guided...

DOI: 10.1016/j.yebeh.2024.109778 Full text Anxiety Depression Mindfulness Epilepsy +1