Psychoactive substances 25H-NBOMe and 25H-NBOH induce antidepressant-like behavior in male rats.
European Journal of Pharmacology September 15, 2023 Barbara G Ferri, Cintia O De Novais, Raquel S Bonani et al. 11 citations
Ring-substituted phenethylamines are believed to induce psychedelic effects primarily by interacting with 5-hydroxytryptamine 2 (5-HT2A) receptors in the brain. We assessed the effect of the psychedelic substances 25H-NBOMe and 25H-NBOH on the depressive-like behavior of male adult rats. Naive Wistar rats were divided into groups to assess the effects of different doses (0.1 mg/kg, 1 mg/kg, and...
DOI: 10.1016/j.ejphar.2023.175926 (opens in new tab)
Full text (opens in new tab)
Depression
Forced swimming test
Psychedelics