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Anesthesiology October 1, 2011 Edgar Alfonso Romero-Sandoval 21 citations
Dartmouth Medical School, Dartmouth College, Lebanon, New Hampshire. edgar.a.romero-sandoval@dartmouth.eduA LARGE population of patients concomitantly experiences chronic pain and depression or symptoms of depression (52% in pain clinics, or 85% in chronic facial pain dental clinics, for example).1How these two syndromes coexist, interact, reinforce each other, and/or are maintained is poorly...
Anesthesiology October 1, 2011 Jing Wang, Yossef Goffer, Duo Xu et al. 171 citations
BACKGROUND: Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with chronic pain and whether this antidepressant effect depends on its...
臺灣精神醫學 September 1, 2011 Chun‐Yi Lee, Jung-Kwang Wen
Objective: A socio-cultural model of depression in Confucianism-oriented societies has the basic assumption that its psychopathology is determined by the disturbance of a harmonious relationship with others. We present a case study in the context of the socio-cultural background to address the relevant issues regarding mental health. Case Report: A 46-year-old housewife patient with major...
Pharmacopsychiatry September 1, 2011 Milan Scheidegger, Anke Henning, Martin Walter et al.
Background: Ketamine is a potent NMDA receptor antagonist with rapid antidepressant properties at subanaesthetic doses. This multimodal imaging study reveals the effects of a subanaesthetic ketamine infusion on fMRI-BOLD responses during an emotional processing task and their relationship to glutamatergic metabolite concentrations in the pregenual anterior cingulate cortex (PACC) assessed by...
Cognitive and Behavioral Practice August 1, 2011 Stuart J. Eisendrath, M. Chartier, Maura Mclane
Major depressive disorder (MDD) is currently ranked the third leading cause of disability in the world. Treatment-Resistant Depression (TRD) causes the majority of MDD's disability. Strikingly, 50% of individuals with MDD will fail to remit with two adequate trials of antidepressant medications, thus qualifying as treatment resistant. Current pharmacological and psychotherapeutic treatment...
Journal of Consulting and Clinical Psychology July 18, 2011 Nicole Geschwind, Frenk Peeters, Marjan Drukker et al. 440 citations
OBJECTIVE: To examine whether mindfulness-based cognitive therapy (MBCT) increases momentary positive emotions and the ability to make use of natural rewards in daily life. METHOD: Adults with a life-time history of depression and current residual depressive symptoms (mean age = 43.9 years, SD = 9.6; 75% female; all Caucasian) were randomized to MBCT (n = 64) or waitlist control (CONTROL; n =...
Behavioural Brain Research June 6, 2011
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Psychology and Psychotherapy Theory Research and Practice June 2011 Johannes Michalak, Anne Hölz, Tobias Teismann
In mindfulness-based cognitive therapy (MBCT), it is proposed that training in mindfulness should reduce the tendency of formerly depressed patients to enter into ruminative thinking, thus reducing their risk of depressive relapse. However, data showing that rumination is associated with depressive relapse are lacking. In an uncontrolled study with 24 formerly depressed patients, rumination was...
Progress in Neuro-Psychopharmacology and Biological Psychiatry June 1, 2011 Lobna Ibrahim, Nancy Diazgranados, David A. Luckenbaugh et al.
Ketamine rapidly improves depressive symptoms in patients with treatment-resistant major depressive disorder (MDD) who do not respond to multiple standard antidepressants. However, it remains unknown whether ketamine is equally effective in patients with MDD who previously also did not respond to electroconvulsive therapy (ECT). This study compared 17 patients with treatment-resistant MDD who...
Complementary Therapies in Clinical Practice May 25, 2011
Meditation for the management of adjustment disorder anxiety and depression.