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Depression: all studies

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Research

Psychometric Properties of Wong’s Self-Transcendence Measure-Brief Among Spanish Older People

Joaquín García-alandete preprint

Abstract Self-transcendence can be defined as what goes beyond one’s limitations and difficulties in life in order to serve or connect with something greater. Self-transcendence is related to both mental and physical health in older people, so it is important to have instruments to measure it properly. This study analyzes the psychometric properties of Wong’s Self-Transcendence Measure-Brief...

Default Mode Network Detection using EEG in Real-time

Navin Cooray, Chetan Gohil, Brendan Harris et al. preprint

Abstract Mental health disorders affect countless people worldwide and present a major challenge for mental health services, which are struggling with the demand on a global scale. Recent studies have indicated that activity of the brain’s Default Mode Network (DMN) could prove insightful in monitoring patient recovery from depression and has been used as a therapeutic target itself. An...

Disruptions of default mode network and precuneus connectivity associated with cognitive dysfunctions in tinnitus

Stephanie Rosemann, Josef P. Rauschecker preprint

Tinnitus is the perception of a ringing, buzzing or hissing sound “in the ear” without external stimulation. Previous research has demonstrated changes in resting-state functional connectivity in tinnitus, but findings do not overlap and are even contradictory. Furthermore, how altered functional connectivity in tinnitus is related to cognitive abilities is currently unknown. Here we...

Increased Default Mode Network Connectivity and Temperament Predict Internalizing Symptoms in Early Childhood

Halle Miller, Johanna Chajes, Tobias Grossmann preprint

Abstract This study investigates the early neural and temperament precursors to internalizing psychopathology. Increased default mode network (DMN) functional connectivity and decreased frontoparietal network (FPN) connectivity are established neural signatures of internalizing disorders in adults, but it is unknown if these patterns represent early-emerging vulnerability. In a community sample...

Oscillatory default mode network coupling in concussion

B.T Dunkley, Karolina Urban, L. Da Costa et al. preprint

Abstract Background Concussion is a common form of mild traumatic brain injury (mTBI). Despite the descriptor ‘mild’, a single injury can leave long-lasting and sustained alterations to brain function, including changes to localised activity and large-scale interregional communication. Cognitive complaints are thought to arise from such functional deficits. We investigated the impact of injury...

Altered resting-state connectivity within default mode network associated with late chronotype

Charlotte Mary Crisp, Ray Norbury preprint

Current evidence suggests late chronotype individuals have an increased risk of developing depression. However, the underlying neural mechanisms of this association are not fully understood. Forty-six healthy, right-handed individuals free of current or previous diagnosis of depression, family history of depression or sleep disorder underwent resting-state functional Magnetic Resonance Imaging...

Investigation of Default Mode Network by very low frequency EEG network analysis

Sho Ageno, Keiji Iramina

One of the resting state networks is the default mode network (DMN); the DMN is primarily concerned with self-perception, orientation, and memory. Although EEG-DMN has been suggested to be active in the ultra-low frequency band below 1 Hz based on fMRI studies, the characteristics of the network have not yet been elucidated. In this study, we measured EEG-DMN during the eye-closed resting...

Synchronous online group MBCT vs guided asynchronous iMBCT in depressed sample: randomized clinical trial with a 3-month follow-up

Jan Wardęszkiewicz, Paweł Holas, Gerhard Andersson preprint

Abstract Background Online Mindfulness-Based Cognitive Therapy (iMBCT) is a promising intervention for mental health, but its effectiveness in reducing depressive symptoms remains underexplored. While key mechanisms of change have been identified in traditional MBCT, their role in online delivery formats needs further investigation. Methods In this randomized clinical trial, 170 individuals...

A Computational Theory of Mindfulness Based Cognitive Therapy from the “Bayesian Brain” Perspective

Zina-Mary Manjaly, Sandra Iglesias preprint

Mindfulness Based Cognitive Therapy (MBCT) was developed to combine methods from cognitive behavioural therapy and meditative techniques, with the specific goal of preventing relapse in recurrent depression. While supported by empirical evidence from multiple clinical trials, the cognitive mechanisms behind the effectiveness of MBCT are not well understood in computational (information...

Mindfulness-Based Stress Reduction Specifically Improves Social Anhedonia among Adults with Chronic Stress

Corinne Carlton, Ligia Antezana, Katelyn Mallory Garcia et al. preprint

This randomized controlled trial examined the effects of mindfulness on anhedonic symptoms in a sample of adults reporting high levels of chronic stress. Meditation-naïve adults (N=68, Mage=32, 62% female) were randomized to either an 8-week MBSR intervention group (N=35), or to a waitlist control group (N=33). We hypothesized that changes in mindfulness would mediate the relationship between...