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Depression: all studies

Page 1030 of 1,034: studies 10,291 to 10,300 of 10,336, newest first. Back to the depression overview

Research

A Literature Review on Vipassana Meditation: Psychological Treatment and Social Benefits for Harmonizing the Inner Self and Society

Feri Sulianta preprint

This literature review examines Vipassana meditation as a multifaceted practice with significant psychological and social benefits. Rooted in ancient Indian traditions and revived in the 20th century by S.N. Goenka, Vipassana meditation focuses on self-observation and mindfulness to cultivate deep self-awareness and ethical living. This review synthesizes historical, empirical, and theoretical...

The Role of Mindfulness -Based Cognitive Therapy to Reduce Depressive Symptoms in Older Adults (Case Study)

Moustafa Yacoub preprint

This case study examines the application and effectiveness of MBCT in reducing depressive symptoms in a 72-year-old man presenting with moderate depression, chronic health issues, and social isolation. The client participated in an 8-week MBCT program tailored for older adults. Assessment tools included the Geriatric Depression Scale (GDS-15), the Mini-Mental State Examination (MMSE), weekly...

How Ketamine Became an Antidepressant

Vincent Joralemon preprint

Ketamine’s path from anesthetic to antidepressant reframed treatment-resistant depression (TRD) by shifting focus from monoamines to glutamate/NMDA modulation. This Article traces the science (from Yale–NIMH pilot work through Zarate 2006), synthesizes evidence across routes of administration (IV, IM, oral, sublingual, intranasal) with bioavailability tradeoffs, and explains why esketamine...

The Relative Importance of Mindfulness Facets and Their Interactions: Relations to Psychological Symptoms in Chronic Pain

Zahra Azizi, Gholamreza Jandaghi, Manijeh Firoozi et al. preprint

Abstract Objectives This study had three objectives: first, to investigate the relative importance of the five mindfulness facets to negative affect (NA) among patients with chronic musculoskeletal pain; second, to test the hypothesis that observing is associated with lower NA only if occurs in an accepting manner; and third, to investigate the relation between mindfulness and...

The Influence of Mindfulness Meditation Versus CBT for Anxiety on Emotional Distress and Attitudes Towards Seeking Mental Health Treatment

Daniela Aisenberg-Shafran, Liav Shturm preprint

Abstract Older adults often avoid seeking psychological treatment, challenging their ability to adaptively deal with anxiety, stress and depression. The aim of the current study was to compare the effects of a mindfulness intervention vs. cognitive-behavioral-therapy (CBT) on measures of emotional distress and attitudes towards seeking mental-health treatment among older adults. Twenty-four...

Efficacy and mechanisms of internet-delivered MBCT for adjustment disorder during the COVID-19 pandemic: A randomized controlled trial

Paweł Holas, Jan Michał Wardęszkiewicz, Malgorzata Grochowska et al. preprint

Background: Adjustment Disorder (AjD) is a common stress-related condition, yet evidence-based interventions remain scarce. Mindfulness-Based Cognitive Therapy (MBCT) targets transdiagnostic mechanisms such as cognitive fusion and low self-compassion, which may be particularly relevant for AjD.Objective: This randomized controlled trial tested the efficacy of a brief, guided, asynchronous...

Development of the therapeutic alliance and its association with treatment outcome in internet-based Mindfulness-Based Cognitive Therapy (eMBCT) compared to group-based MBCT (MBCT) for distressed cancer patients (Preprint)

Else Bisseling, Linda Cillessen, Philip Spinhoven et al.

BACKGROUND Mindfulness-Based Cognitive Therapy (MBCT) is an evidence-based group-based psychological treatment in oncology, resulting in reduction of depressive and anxiety symptoms. Internet-based Mindfulness-based Cognitive Therapy (eMBCT) has been found to be an effective alternative for MBCT. The therapeutic alliance, i.e. the bond between therapist and patient, is known to have a...

Effect of psycho-education and mindfulness-based stress reduction on psychological stress of carers of relatives with dementia: A randomized controlled trial

Mohsen Janghorbani, Victoria Omranifard, Azam Mansourzadeh preprint

Abstract Background and Objectives The intention of this randomized controlled trial was to compare the relative usefulness of psycho-education (PE) and mindfulness-based stress reduction (MBSR) training programs on carers of relatives with dementia (RWD). Materials and Methods An eight-week, randomized, controlled trial was accomplished from March to December 2020. Ninety carers of RWD were...

Death and Near-Death Experiences in Ketamine and Psychedelic Therapy

Michael Alvear preprint

Patients undergoing ketamine-or psychedelic-assisted therapy for cancer-related distress, treatment-resistant depression, or end-of-life existential fear frequently report experiences resembling death or near-death: a sense of leaving the body, encountering something transcendent, or having died and returned. This synthesis reviews peer-reviewed evidence on how often this occurs, why it may...

Does Practice Make Perfect? Functional Connectivity of the Salience Network and Somatosensory Network Predicts Response to Mind-Body Treatments for Fibromyalgia

Sonia Medina, Owen G. O’Daly, Matthew A. Howard et al. preprint

Abstract Mind-body treatments can improve coping mechanisms, and occasionally perceived pain, in individuals with Fibromyalgia syndrome (FMS). However, their mechanisms-of-action remain unclear and predictors of treatment response are lacking. We employed resting-state blood oxygen level dependent (rsBOLD) functional magnetic resonance imaging (fMRI) to address this need by examining changes in...