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Matthew A. Howard

2 papers in the library · 48 citations · publishing 2022

Papers

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Differential contributions of serotonergic and dopaminergic functional connectivity to the phenomenology of LSD

Psychopharmacology March 24, 2022 Timothy Lawn, Ottavia Dipasquale, Alexandros Vamvakas et al. 48 citations

Abstract Rationale LSD is the prototypical psychedelic. Despite a clear central role of the 5HT 2a receptor in its mechanism of action, the contributions of additional receptors for which it shows affinity and agonist activity remain unclear. Objectives We employed receptor-enriched analysis of functional connectivity by targets (REACT) to explore differences in functional connectivity (FC)...

Does Practice Make Perfect? Functional Connectivity of the Salience Network and Somatosensory Network Predicts Response to Mind-Body Treatments for Fibromyalgia

Sonia Medina, Owen G. O’Daly, Matthew A. Howard et al.

Abstract Mind-body treatments can improve coping mechanisms, and occasionally perceived pain, in individuals with Fibromyalgia syndrome (FMS). However, their mechanisms-of-action remain unclear and predictors of treatment response are lacking. We employed resting-state blood oxygen level dependent (rsBOLD) functional magnetic resonance imaging (fMRI) to address this need by examining changes in...