Skip to content

Depression: all studies

Page 1026 of 1,035: studies 10,251 to 10,260 of 10,348, newest first. Back to the depression overview

Research

Perceived changes in the self following an MBCT protocol: a qualitative study to inform further theory development

Mental Health and Social Inclusion December 14, 2026 Philippine Chachignon, Emmanuelle Le Barbenchon, Carine Finiels et al.

Purpose Mindfulness-based cognitive therapy (MBCT) is a flagship intervention addressing depressive disorders that are distressing for the self and socially impairing. While psychological processes such as self-regulation, meta-awareness and self-transcendence account for its efficacy, these are often examined in isolation, and the social aspects of the self remain under-researched. Moreover,...

Embodied Transformation: Psychedelic Therapy Through the Lens of Merleau-Ponty’s Phenomenology

Integrative Psychological and Behavioral Science December 1, 2026 Zinet Ritschel, Brady Wagoner

Abstract This paper develops a phenomenological account of the therapeutic significance of psychedelic-induced mystical experience, drawing on the philosophy of Maurice Merleau-Ponty. The central argument holds that the enduring therapeutic benefits of psychedelics emerge through a radical transformation in the structure of lived experience. Two prominent objections to the therapeutic value of...

Voided REM Sleep (V-REM)

Mouhammad Ousmane Ndiaye

Roughly 40% of patients with post-traumatic stress disorder (PTSD) and roughly 31% of patients with major depressive disorder (MDD) fail to respond to first-line treatment, and the two disorders co-occur in approximately half of all cases. No objective, nocturnal biomarker currently distinguishes which patients will fail to recover, or why. This paper proposes that a subgroup of...

Contexts, Risks, and Affordances among Autistic Adults Using Psychedelics for Therapeutic Purposes: A Naturalistic, Mixed-Methods Study

Alvita Sam, Alexander de Foe, Aspasia Stacey Rabba et al. preprint

Background: Autistic adults are under-investigated in psychedelic research, despite speculated elevated likelihood of substance use for therapeutic and recreational purposes.Aims: This study explored contexts of naturalistic psychedelic use and wellbeing and mental health indicators in a group of Autistic adults using psychedelics for therapeutic purposes, and compared these with the broader...

Psilocybin-Assisted Therapy for Existential Distress in Serious and Life-Limiting Illness: Emerging Trial Evidence, Barriers to Access, and the Case for Individualized Eligibility

Janis Ancans preprint

AbstractBackground. Existential distress and treatment-resistant depression are common and difficult to manage in patients with serious and life-limiting illnesses. Psilocybin-assisted therapy has shown early promise for these conditions, but access outside research settings remains narrow, inconsistent, expensive and often shaped by outdated eligibility rules. These include extremely limited...

Quality of Life and the Case for Consent-Based Psilocybin Access – Questions on the Regulatory Framework and Cost

Janis Ancans preprint

Legal access to psilocybin almost always requires a medical diagnosis first, usually treatment-resistant depression (TRD) or severe PTSD, as though informed consent alone was not sufficient. This article makes two connected arguments. Extending the autonomy argument already accepted for terminally ill patients, competent adults who understand the potential benefits and risks of a psilocybin...

Spirituality Matters in Deconstructive Meditation: Comparing Secular and Buddhist-Based Mechanisms of Change in Depressive Vulnerability

Céline Stinus, Sophie Berjot preprint

This exploratory study extends a previously implemented randomized protocol to examine whether incorporating Buddhist-based spiritual and philosophical components into deconstructive meditation is associated with different patterns of psychological change. We compared secular deconstructive meditation (S-SI; n = 49), Buddhist-based deconstructive meditation (B-SI; n = 53), and a waitlist...

Mindfulness and Legal Practice: A Preliminary Study of the Effects of Mindfulness Meditation and Stress Reduction in Lawyers

John Paul Minda, Jeena Cho, Emily Nielsen et al. preprint

Research has shown that lawyers often experience symptoms of depression, anxiety, and stress in their lives. Mindfulness meditation may be an effective way to reduce the many negative effects associated with work stress. We asked a group of 46 lawyers to participate in an eight week mindfulness meditation program that was designed for lawyers. The mindfulness program was based on The Anxious...

The neural correlates of two forms of spiritual love: an EEG study

E. S. Louise Faber preprint

Abstract: Spiritual practices are gaining an increasingly wider audience as a means to enhance positive affect in healthy individuals and to treat neurological disorders such as anxiety and depression. The current study aimed to examine the neural correlates of two different forms of love generated by spiritual practices using EEG; love generated during a loving kindness meditation performed by...