Journal of Mental Science
July 1, 1952
Ashley A. Robin, E. J. Harrison
A search of the literature has not revealed a report of the depersonalization syndrome occurring in identical twins, although Palmer (1946) published a report of twins in which one patient was described as suffering from “all round loss of interest with some depression…. His thoughts … milled round in a ceaseless turmoil concerning his loss of contact with people and things. There was some...
American Journal of Psychiatry
June 1, 1952
Charles Savage
137 citations
Lysergic acid diethylamide (LSD-25 Sandoz) given orally in single doses as low as 20 micrograms produces depersonalization, derealization, and increased imagery in "normal" individuals. Larger doses are required to produce the same effect in psychotic patients. Of 15 patients with depressive reactions, 3 recovered and 4 improved after one month's treatment with daily oral doses of 20-100...
Journal of Mental Science
1947
G. Tayleur Stockings
Depersonalization, or feeling of unreality, is a symptom which may occur as part of several psychiatric conditions, such as hysteria, anxiety and obsessional states, and some forms of schizophrenia and endogenous depression. The true derealization-depersonalization syndrome, however, in which the unreality symptom is the primary disturbance, is a quite peculiar and distinctive condition, which...
Home healthcare now
Jala Sireesha, Jayasree Manukinda, Sudhindra Vooturi et al.
Progressive functional decline and behavioral disturbances in people with dementia place sustained emotional and practical demands on family caregivers, often resulting in chronic stress, anxiety, depression, and a high perceived caregiving burden. This pilot study examined the effects of an 8-week online Mindfulness-Based Stress Reduction (MBSR) program on psychological burden and well-being...
Journal of Clinical Psychopharmacology
John L. Havlik, Sayana Isaac, Pralahad Raman et al.
With a rapid rise in clinical trials investigating psychogenic substances, the field faces considerable concerns regarding transparency and conflicts of interest. This study aims to systematically characterize ongoing NIH-registered clinical trials investigating psychogenic substances for psychiatric disorders as of late 2024, including research protocols, institutional settings, and funding...
The Journal of cardiovascular nursing
Angela Rao, Robert Zecchin, Phillip J Newton et al.
2 citations
Comorbid depression and/or anxiety symptoms occur in 25% of patients attending cardiac rehabilitation (CR) programs and are associated with poorer prognosis. There is a need to evaluate psychological interventions, including meditation, that have potential to improve psychological health in CR programs. The aim of this study was to determine the feasibility and acceptability of integrating a...
Journal of Addiction Medicine
Babak Tofighi, Christina Marini, Joshua D Lee et al.
1 citation
Recent findings support the provision of meditation-based interventions (MBIs) in primary care. However, the acceptability of MBI among patients prescribed medications for opioid use disorder (eg, buprenorphine) in primary care remains unclear. This study assessed experiences and preferences for adopting MBI among patients prescribed buprenorphine in office-based opioid treatment (OBOT). This...
Journal of Addiction Medicine
Ameya Krishnan
3 citations
Among 20.4 million US adults diagnosed with substance use disorders (SUDs), up to 60% return to use despite treatment or attempted abstinence. Standard care for SUDs is pharmacotherapy and/or behavioral interventions in either an inpatient or outpatient setting. Both national and international epidemiological data suggest this approach to treatment is insufficient and use of an integrative...
Journal of Clinical Psychopharmacology
Vivian Kim, Scott M Wilson, Mary E Woesner
3 citations
Following a decades-long decline in psychedelic research resulting from social, political, and legislative factors, there has been greatly renewed interest in these compounds' ability to treat psychiatric disorders. Classic psychedelics, encompassing both natural and synthetic psychoactive compounds, are characterized by their action as agonists or partial agonists of serotonin...
Clinical Neuropharmacology
Jiancheng Qiu, Yifei Gong, Xiucui Zhang et al.
4 citations
This study was aimed to investigate the effectiveness of mindfulness-based cognitive therapy (MBCT) on depressive symptoms, brain potential, and neuroimmunoinflammatory factors in patients with depression. Sixty-four eligible patients according to the inclusion criteria were randomly divided into the control group and the observation group, with 32 patients in each group. The control group...