Addiction Biology
January 2010
Rocío Martín‐Santos, Marta Torrens, Sandra Poudevida et al.
A 3-year longitudinal prospective study was conducted to compare the incidence of substance use disorders (SUD) and non-substance use disorders (NSUD) among ecstasy users and two control groups: one of cannabis users and the other of non-drug users. The 5-HTTLPR polymorphism related to NSUD was also studied. A total of 94 subjects were included: 37 ecstasy users, 23 cannabis users and 34...
Neuropsychobiology
2010
A J Matthews, R Bruno
Methylenedioxymethamphetamine affects the central serotonergic system, and there is some evidence for an association between ecstasy use (drugs sold as methylenedioxymethamphetamine) and depression. The aim of the present study was to investigate the incidence of self-reported depression and associated help-seeking among a sample of regular ecstasy users. A further aim was to examine the...
December 6, 2009
I. Dowbiggin
Reviewed by: Psychedelic Psychiatry: lsd from Clinic to Campus Ian Dowbiggin Psychedelic Psychiatry: LSD from Clinic to Campus. Erika Dyck. Baltimore: Johns Hopkins University Press, 2008. Pp. 216, $35.00 cloth I’ve lived long enough to remember the 1960s when movies such as Reefer Madness, a film about the health dangers of marijuana, were considered square, moralistic, and unscientific. Then...
L'Encephale
December 1, 2009
Y Morvan, J Rouvier, J-P Olié et al.
Introduction: The use of illicit drugs by students and the possible psychological repercussions in this population of young adults is an important public health issue. While some data in the literature suggest a relationship between cannabis and the occurrence of mental health disorders, and in particular psychotic illnesses, epidemiologic surveys have shown that cannabis is the most consumed...
Psychological Assessment
December 2009
Margreet Oorschot, Thomas Kwapil, Philippe Delespaul et al.
There is an expanding interest to study psychosis in the realm of daily life. The study of the person in the context of daily life may provide a powerful addition to more conventional and cross-sectional research strategies in the study of psychosis. This article first discusses the nature of experience sampling research in psychosis and demonstrates the feasibility and validity of studies...
Psychopharmacology
November 1, 2009
Dagmar Koethe, Carolin Hoyer, F Markus Leweke
Model psychosis is characterised by experimentally induced symptoms of withdrawal from reality, frequently accompanied by perceptual disturbances, thought disorders, delusional ideas and sometimes by hallucinations. These "altered states of consciousness" provide a long-standing and valid approach to enhance our understanding of certain aspects of schizophrenia. Targeting the endocannabinoid...
Brain Research
October 6, 2009
Gloria M P Roberts, Liam Nestor, Hugh P Garavan
It has been consistently shown that ecstasy users display impairments in learning and memory performance. In addition, working memory processing in ecstasy users has been shown to be associated with neural alterations in hippocampal and/or cortical regions as measured by functional magnetic resonance imaging (fMRI). Using functional imaging and a face-learning task, we investigated neural...
The Journal of Clinical Psychiatry
October 1, 2009
Daphne Simeon, David S Kozin, Karina Segal et al.
Previous studies have documented that in a substantial minority of individuals with depersonalization disorder, onset is first triggered by illicit drug ingestion. The goal of this study was to systematically compare a large sample of individuals with drug-initiated (D) versus non-drug-initiated (ND) chronic depersonalization. We conducted an internet survey of 394 adults endorsing DSM-IV-TR...
September 30, 2009
John Mann, John Emsley, Philip Ball et al.
Timothy Leary's advice to "tune in, turn on and drop out" was a 1960s exhortation to experiment with LSD, but humans had been consuming ergot alkaloids related to lysergic acid diethylamide for at least a thousand years. Opium has been around even longer with its medicinal uses being known to the Ancient Sumerians as long ago as 3400 BC. This is the first book to cover all of the major...
Journal of Clinical and Experimental Neuropsychology
September 30, 2009
Karen L. Hanson, Mónica Luciana
34 citations
This study and our previous report (Hanson, Luciana, & Sullwold, 2008) suggest that moderate MDMA use does not lead to persistent impairments above and beyond that associated with generally heavy drug use, but polydrug use may lead to dose-related temporal and frontoparietal dysfunction. Marijuana use may be particularly problematic. Cause-effect relations are unclear.