Headache: The Journal of Head and Face Pain
February 25, 2011
Christina Sun‐edelstein, Alexander Mauskop
71 citations
There is a growing body of evidence supporting the efficacy of various complementary and alternative medicine approaches in the management of headache disorders. These treatment modalities include nutraceutical, physical and behavioral therapies. Nutraceutical options comprise vitamins and supplements (magnesium, riboflavin, coenzyme Q 10 , and alpha lipoic acid) and herbal preparations...
Frontiers in Behavioral Neuroscience
2011
Eva María Marco
139 citations
Public concern on mental health has noticeably increased given the high prevalence of neuropsychiatric disorders. Cognition and emotionality are the most affected functions in neuropsychiatric disorders, i.e., anxiety disorders, depression, and schizophrenia. In this review, most relevant literature on the role of the endocannabinoid (eCB) system in neuropsychiatric disorders will be presented....
PLoS One
2011
Joost Wiskerke, Nicky Stoop, Dustin Schetters et al.
It is well known that acute challenges with psychostimulants such as amphetamine affect impulsive behavior. We here studied the pharmacology underlying the effects of amphetamine in two rat models of impulsivity, the 5-choice serial reaction time task (5-CSRTT) and the delayed reward task (DRT), providing measures of inhibitory control, an aspect of impulsive action, and impulsive choice,...
PLoS One
2011
Lisa K Brents, Emily E Reichard, Sarah M Zimmerman et al.
K2 products are synthetic cannabinoid-laced, marijuana-like drugs of abuse, use of which is often associated with clinical symptoms atypical of marijuana use, including hypertension, agitation, hallucinations, psychosis, seizures and panic attacks. JWH-018, a prevalent K2 synthetic cannabinoid, is structurally distinct from Δ(9)-THC, the main psychoactive ingredient in marijuana. Since even...
VCU Scholars Compass
2011
D. Matthew Walentiny
Cannabinoid agonists (e.g., THC) dose-dependently decrease locomotor activity and body temperature and produce antinociception and catalepsy. Drugs that produce this tetrad of effects within a limited dose range are likely to function as CB1 receptor agonists. A structure activity relationship study from our laboratory investigating analogs of the CB1 antagonist rimonabant revealed that certain...
Pharmacological Reports
2011
Jenny L Wiley, Rhys L Evans, Darren B Grainger et al.
Adolescents and young adults of both sexes are the primary consumers of "club" drugs; yet, most of the mechanistic preclinical research in this area has been performed in adult male rodents. The purpose of this study was to evaluate the acute and repeated effects of drugs that are commonly abused by adolescents in female adolescent and adult rats in a rodent model of behavioral sensitization....
Journal of Psychoactive Drugs
2011
Donald R Wesson
22 citations
The 1960s were a time of social upheaval, wars, vibrant creativity and missed opportunity. Mainstream culture and a psychedelic drug-using counterculture shared a belief in "better living through chemistry'," but they disagreed about the particular chemistry. The Vietnam war and the cold war with the Soviet Union, racial discrimination, and gender roles fueled political activism. "Yes we can"...
Current Drug Abuse Reviews
September 1, 2010
Marinus N. Verbaten
10 citations
A quantitative meta-analysis was carried out on the chronic effects of ecstasy use on working memory (WM), assumed to consist of a central executive (CE) and four executive subcomponents: Updating, Attention shifting, Inhibition and Access to long term memory. Publications dating from January 1998 to January 2008 were only included when they fulfilled the criteria for a meta-analysis (number of...
Journal of Psychoactive Drugs
September 1, 2010
Pearl P Nyi, Emily P Lai, Diana Y Lee et al.
16 citations
An Internet-based survey of Salvia divinorum ("salvia") users was conducted to identify correlates surrounding its use. Salvia-knowledgeable persons were recruited via "social networking Internet websites" (n = 23) where notices were posted on recreational salvia group message boards (n = 69). Data collection included demographics, use circumstances, experiences, and age (current and at first...
M/C Journal
August 19, 2010
Cornelia Sears, Jessica Johnston
5 citations
We take as our subject what many would deem a waste of good celluloid: the degraded cultural form of the stoner film. Stoner films plot the experiences of the wasted (those intoxicated on marijuana) as they exhibit wastefulness—excessiveness, improvidence, decay—on a number of fronts. Stoners waste time in constantly hunting for pot and in failing to pursue more productive activity whilst...