ILAR Journal
2011
Divya Ramesh, Joel E Schlosburg, Jason M Wiebelhaus et al.
Marijuana (Cannabis sativa) is the most commonly used illicit drug worldwide as well as in the Unites States. Prolonged use of marijuana or repeated administration of its primary psychoactive constituent, Δ9-tetrahydrocannabinol (THC), can lead to physical dependence in humans and laboratory animals. The changes that occur with repeated cannabis use include alterations in behavioral,...
Indian Journal of Psychiatry
January 2011
Shubhangi R Parkar, Seethalakshmi Ramanathan, Narendra Nair et al.
Cannabis has been associated with transient psychotic states; however, the causal relationship between cannabis and schizophrenia continues to remain a matter of debate. Epidemiological and some biological studies hint at cannabis being an independent risk factor for schizophrenia; this has not been definitively proved. We aimed to understand the patterns of glucose uptake in important brain...
Brain Connectivity
2011
Dae-Jin Kim, Patrick D. Skosnik, Hu Cheng et al.
Endocannabinoid receptors modulate synaptic plasticity in the brain and may therefore impact cortical connectivity not only during development but also in response to substance abuse in later life. Such alterations may not be evident in volumetric measures utilized in brain imaging, but could affect the local and global organization of brain networks. To test this hypothesis, we used a novel...
Neuropsychopharmacologia Hungarica
2011
Zoltán Makkos, Lilla Fejes, Gabriella Inczédy-Farkas et al.
3 citations
Marijuana (cannabis) is the most commonly abused drug by adolescents and young adults and also by people with schizophrenia or other psychotic disorders. An increasing number of studies suggest that regular cannabis users can show psychotic episodes similar to schizophrenic disorders but it still unclear if cannabis induced psychotic disorder is a distinct entity requiring special therapy or...
Indian Journal of Psychiatry
2011
Amresh Shrivastava, Megan Johnston, Ming T. Tsuang
69 citations
This review considers the effects of cannabis on cognitive functioning, in both short and long term. Although the general impression supported by many studies is that cannabis causes cognitive decline, particularly with long-term usage, some research suggests that this may not be the case. Nevertheless, certain specific neuropsychological parameters have been found to be affected. Most commonly...
2011
M. Konings
Chapter IVValidity and reliability of the CAPE: a self-report instrument for the measurement of psychotic experiences in the general population 51 Chapter V Early exposure to cannabis and risk for psychosis in young adolescents in Trinidad 61Chapter VI Evidence from two prospective population-based studies for interaction between cannabis use and childhood trauma on psychosis risk.
Frontiers in Behavioral Neuroscience
2011
Liana Fattore, Walter Fratta
443 citations
Synthetic cannabinoids are functionally similar to delta9-tetrahydrocannabinol (THC), the psychoactive principle of cannabis, and bind to the same cannabinoid receptors in the brain and peripheral organs. From 2008, synthetic cannabinoids were detected in herbal smoking mixtures sold on websites and in "head shops" under the brand name of Spice Gold, Yucatan Fire, Aroma, and others. Although...
Farmacognosia
2011
F. Capasso
Gli allucinogeni sono sostanze psicoattive capaci di causare ‘sostanziali e transitorie modificazioni della percezione, del pensiero e dell’umore’. Possono essere classificate in base al loro meccanismo d‘azione oppure in base alla loro struttura chimica.
Journal of Psychoactive Drugs
2011
Radmila Lorencova
14 citations
This study focuses on measuring the spirituality of alcohol and marijuana users, using the new and exclusively Czech measuring tool, the Prague Spiritual Questionnaire (PSQ). The data from 155 respondents shows that users of both marijuana and alcohol scored significantly higher in the mysticism dimension of spirituality than those who only drank alcohol. People who mentioned that the specified...
Neuropsychopharmacology
December 8, 2010
Disruption of frontal θ coherence by Δ9-tetrahydrocannabinol is associated with positive psychotic symptoms.