Disruption of frontal θ coherence by Δ9-tetrahydrocannabinol is associated with positive psychotic symptoms.

Study at a glance

Characteristics	Observational cohort Peer reviewed
Population	Participants administered THC (specific population not stated)
Intervention	Δ9-tetrahydrocannabinol
Topics	Cannabis
Key findings	THC disrupts frontal theta coherence, and this disruption is associated with positive psychotic symptoms.

Other observational and cohort studies on cannabis, most cited first.

Study	Year	Design	Participants
High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population	2009	Case-control study	n = 454
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population	2013	Observational study
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people	2000	Observational
Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline	2011	Observational cohort	n = 1,923
Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and...	2005	Observational cohort	n = 535