European Journal of Pharmacology
January 26, 2007
Daniela Braida, Valeria Limonta, Lorenzo Malabarba et al.
The mechanism mediating the effects of cannabinoids on anxiety-related responses appear to involve cannabinoid CB1 and non-CB1 receptors. However, other neurotransmitters may play a role in such effect. This study shows evidence of an interaction between endocannabinoid system and serotonin (5-HT), 1A receptor subtype on anxiety-like behavior in Sprague-Dawley rats. The exogenous cannabinoid...
Addiction
January 15, 2007
Harold A. Pollack, Peter H. Reuter
7 citations
Recent studies have increased long-standing concerns that cannabis use can trigger or exacerbate psychosis and schizophrenia. Widely publicized, these findings have led to calls for tougher laws and/or more aggressive enforcement of prohibitions against cannabis use and distribution [1]. The findings may be confounded by unobserved factors. Even if they prove broadly correct, these findings...
Socialmedicinsk tidskrift
2007
Peter Allebeck
Det är väl känt att cannabis kan leda till en mängd olika psykiska symtom i direkt anslutning till missbruk eller kort därefter. Frågan om cannabis är en oberoende riskfaktor för schizofreni och andra psykoser har dock varit kontroversiell och under lång tid saknades forskning på området som möjliggjorde bedömning av orsakssambanden. Under senare år har ett antal studier givit starkt stöd för...
Neurosciences
2007
B. Issa
Cannabis is one of the oldest, and one of the most widely abused substances. It is available in all parts of the world where it is used commonly as a recreational drug when smoked or consumed in some other ways. It also has some medicinal potential, the reason for which some are calling for its legalization. Cannabis has been associated with several psychiatric problems such as anxiety...
Learning & Memory
2007
Alexander F. Hoffman, Murat Oz, Ruiqin Yang et al.
preprint
Memory deficits produced by marijuana arise partly via interaction of the psychoactive component, Delta(9)-tetrahydrocannabinol (Delta(9)-THC), with cannabinoid receptors in the hippocampus. Although cannabinoids acutely reduce glutamate release and block hippocampal long-term potentiation (LTP), a potential substrate for learning and memory, the consequences of prolonged exposure to...