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July 27, 2022 Rebekah Senanayake
<p>Disruptions to the sense of self are dotted across cultures and times in rituals involving hallucinogens, sensory deprivation, trance possession, and meditation. Much of the research on the self or “ego” suggests that the self is a complicated, multi-faceted entity and that there are many aspects that hold together our ego. Yet, current measurements on ego-dissolution focus on a narrow...
Anthropology of Consciousness July 8, 2022 Bruno Ramos Gomes, Luís Fernando Tófoli 2 citations
ABSTRACT This research qualitatively investigated four treatments for addiction in Brazil that use ibogaine as the main tool in the process. Ibogaine is a substance derived from an African plant, Tabernanthe iboga, traditionally used in its region of origin and which leads to intense sensations during its acute effects and also different experiences of oneself and the surrounding world in the...
Journal of Neurochemistry July 1, 2022 Hannah N Saeger, David E. Olson 59 citations
Psychedelics are increasingly being recognized for their potential to treat a wide range of brain disorders including depression, post-traumatic stress disorder (PTSD), and substance use disorder. Their broad therapeutic potential might result from an ability to rescue cortical atrophy common to many neuropsychiatric and neurodegenerative diseases by impacting neurotrophic factor gene...
SSM: Qualitative Research in Health June 4, 2022 David M. O’shaughnessy, Zoltán Sarnyai, Frances Quirk et al.
Traditional Amazonian medicine, and in particular the psychoactive substance ayahuasca, has generated significant research interest along with the recent revival of psychedelic medicine. Previously we published within-treatment quantitative results from a residential addiction treatment centre that predominately employs Peruvian traditional Amazonian medicine, and here we follow up that work...
International Journal of Environmental Research and Public Health May 29, 2022 Ahmed Al-Imam, Marek A Motyka, Zuzanna Witulska et al. 7 citations
Background: Psychedelics represent a unique subset of psychoactive substances that can induce an aberrant state of consciousness principally via the neuronal 5-HT2A receptor. There is limited knowledge concerning the interest in these chemicals in Poland and how they changed during the pandemic. Nonetheless, these interests can be surveyed indirectly via the web. Objectives: We aim to conduct a...
Columbia University Press eBooks May 13, 2022 G. William Barnard 6 citations
The Santo Daime is a syncretic religion whose spiritual practice is based around the sacramental use of ayahuasca. G. William Barnard—an initiate of the religion and a scholar of religious studies—considers the religious practice and transformative inner experiences of the Santo Daime community.
Frontiers in Psychology May 3, 2022 Débora González, Marc Aixalà, Robert A Neimeyer et al. 15 citations
Rationale Many psychedelic experiences are meaningful, but ineffable. Engaging in meaning-making regarding emerging symbolic content and changing previous schemas have been proposed as mechanisms of change in psychedelic therapy. Objective Firstly, we suggest the implementation of a Restorative Retelling (RR) technique to process and integrate the psychedelic experience into autobiographical...
Neuroscience and biobehavioral reviews April 2022 Pantelis Leptourgos, Vincent Bouttier, Sophie Denève et al.
Psychedelics distort perception and induce visual and multimodal hallucinations as well as synaesthesia. This is in contradiction with the high prevalence of distressing voices in schizophrenia. Here we introduce a unifying account of unimodal and multimodal erroneous percepts based on circular inference. We show that amplification of top-down predictions (descending loops) leads to an...
Journal of Ethnopharmacology March 25, 2022 Ilana Berlowitz, David M O'Shaughnessy, Michael Heinrich et al. 26 citations
Indigenous groups of the Amazon have developed intricate methods for the application of psychoactives, among which particularly the dieta or diet method of Peruvian-Amazonian traditional medicine stands out. It is a retreat-like intervention involving lengthy periods of social, behavioural, and alimentary restrictions, while ingesting specially prepared plant substances. The interplay of the...
Journal of Psychopharmacology March 1, 2022 Max Wolff, Lea J. Mertens, Marie Walter et al. 57 citations
Background: Many benefits and some harms associated with psychedelic use could be attributable to these drugs’ acceptance/avoidance-promoting effects and corresponding changes in psychological flexibility. Underlying psychological mechanisms are insufficiently understood. Aim: The purpose of this study was the validation of a psychological model of acceptance/avoidance-promoting psychedelic...