General Hospital Psychiatry
July 24, 2025
Shizhen Wang, Mengru Wu, Jixiang Wei et al.
6 citations
Anxiety and depression are highly prevalent mental health disorders, imposing significant burdens on individuals and healthcare systems. Mindfulness-based cognitive therapy (MBCT) has demonstrated effectiveness in reducing these symptoms. Electronic health MBCT (eMBCT) offers a scalable alternative, but its efficacy in alleviating anxiety and depression in adults remains unclear. To examine the...
Applied Psychophysiology and Biofeedback
July 22, 2025
Saba Hassanvandi, Reza Mohammadzadegan, Seyed Hassan Saadat et al.
The current trial aimed to assess the effectiveness of Mindfulness-Based Stress Reduction training on salivary cortisol and α-amylase levels, anxiety and depression of students. This research was an experimental trial with a pre-test-post-test design and a control group. The statistical population of the research included all students studying in the universities of Khoy, Iran in 2021. The...
Frontiers in Psychiatry
July 18, 2025
Hui Kou, Wei Luo, Yiwei Wang et al.
2 citations
Background: The present study investigated the sustained effects of a 5-week EmotionCore mindfulness training program on emotion regulation, emotional intelligence (EI), trait mindfulness, depression, and anxiety among 120 undergraduates, while exploring the mediating mechanisms of training effect and heterogeneous effects across subgroups. Methods: Participants were randomly assigned to a...
Fundamental Research
July 16, 2025
C-J Gao, Heming Cheng
A recent study published in Neuron by Tiwari et al . identified the critical role of 5-HT 2A receptor in ventral hippocampal parvalbumin (PV) interneurons (INs) in mediating the acute anxiolytic effects of the serotonergic psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI). This study not only advances psychedelic neuropharmacology but also provides a robust framework for developing novel...
Scientific Reports
July 16, 2025
Junchao Yuan, Luyu Chen, Hongye Geng
1 citation
Anxiety symptoms are highly prevalent among Chinese university students, significantly impairing psychosocial functioning. Although mindfulness has been identified as a protective psychological factor, the precise mechanisms underlying its association with anxiety symptom alleviation remain insufficiently understood. This study investigates the serial mediation effects of rumination and...
Neuropsychopharmacology
July 15, 2025
Maria Beatriz Bistue Millón, Laura Noguera, Diana Bruno et al.
4 citations
This Phase I clinical trial is the first to rigorously evaluate the safety, tolerability, and pharmacokinetics of a novel sublingual formulation of 5-MeO-DMT, administered at sub-psychedelic doses to adults with moderate to high levels of anxiety and/or depression, without formal psychiatric diagnosis or ongoing treatment. Using a double-blind, placebo-controlled design, participants received a...
Archives of Psychiatry and Psychotherapy
July 14, 2025
Patryk Roczon, Paweł Holas, Marzena Rusanowska et al.
Previous studies have found that self-compassion and mindfulness are negatively related to depressive and anxiety symptoms. Still, the mechanisms underlying these relationships in major depression and whether such mechanisms differ in healthy people are poorly understood. In the present study, it was examined whether mindfulness and worrying mediated relationships between self-compassion,...
Psychiatry Research
July 12, 2025
Marianna de Abreu Costa, Patrícia Bado, Maiko Schneider et al.
1 citation
The brain mechanisms underlying patient improvement after interventions remain poorly understood. Identifying the shared and distinct neural pathway between improvement mechanisms across distinct treatment modalities might improve our understanding of brain-behavior relationships and inform personalized approaches. To investigate the neural correlations of symptom improvement in Generalized...
Psychology in the Schools
July 9, 2025
Kenjiro Tsubono, Sachiko Mitoku
Schoolteachers are considered as one of the most stressful professions worldwide. This study aimed to investigate the effect of brief mindfulness meditation practice via video streaming on schoolteachers' mental health. Public school teachers were recruited through paper flyers and relevant social media. Participants were randomly assigned to either the meditation or the control group. Blind...
Explore
July 8, 2025
Ying-Ju Chen, Chiu-Hsiang Lee, Chia-Jung Hsieh et al.
1 citation
Online mindfulness may be an effective non-pharmacological mental health intervention. To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases. In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (N = 47) or the control group (N =...