Effect of online mindfulness intervention on anxiety, depression, and stress in patients with chronic diseases.
Ying-Ju Chen, Chiu-Hsiang Lee, Chia-Jung Hsieh, Pei-Hung Liao, Yu-Da Chen, Kuei-Ru Chou, Shu-Liu Guo, Li-Fang Chang, Tso-Ying Lee
Explore July 8, 2025 DOI: 10.1016/j.explore.2025.103214 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Qualitative Peer reviewed |
|---|---|
| Sample size | 97 |
| Population | Patients with chronic diseases |
| Intervention | Online mindfulness platform |
| Duration | 8-week intervention, assessments at baseline, 4 weeks, and 8 weeks |
| Topics | Anxiety Depression Meditation |
| Keywords | Adults Chronic disease Online mindfulness platform Stress |
| Citations | 1 |
| Key findings | Online mindfulness intervention significantly reduced anxiety at 4 and 8 weeks, and reduced depression and stress at 8 weeks, in adults with chronic diseases. |
Abstract
Online mindfulness may be an effective non-pharmacological mental health intervention. To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases. In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (N = 47) or the control group (N = 50). Anxiety, depression, and stress levels were assessed at baseline, 4 weeks, and 8 weeks after the intervention. The baseline scores of anxiety, depression, and stress between the control and experiment groups were comparable. Online mindfulness intervention significantly reduced anxiety scores at Week 4 and Week 8 (both P < 0.001). In addition, online mindfulness intervention significantly lowered both depression scores and stress levels at Week 8 (both P ≤ 0.002), but not at Week 4. Online mindfulness interventions effectively alleviate anxiety, depression, and stress in patients with chronic diseases. Future qualitative research is recommended to further explore the mechanisms of change at the psychological level.
Comparable studies
Other randomized controlled trials on anxiety, most cited first.
Citations in the library
Cited by 2
- Impact of mindfulness training on depression and walking ability in patients with lower extremity arteriosclerosis obliterans and depression World Journal of Psychiatry August 19, 2026
- The Effects of a Digital Mindfulness Intervention on Mental Health and Vision-Related Quality of Life in Non-infectious Uveitis. Ophthalmology June 1, 2026
Cites 21
- Mechanisms of mindfulness Journal of Clinical Psychology December 29, 2005
- Mindfulness-based interventions: an overall review British Medical Bulletin April 21, 2021
- Mindfulness-Based Stress Reduction as a Stress Management Intervention for Healthy Individuals Journal of Evidence-Based Complementary & Alternative Medicine July 22, 2014
- App‐based mindfulness meditation reduces perceived stress and improves self‐regulation in working university students: A randomised controlled trial Applied Psychology: Health and Well-Being December 27, 2021
- Training-related improvements in mental well-being through reduction in negative interpretation bias: A randomized trial of online socio-emotional dyadic and mindfulness interventions. Journal of Affective Disorders June 1, 2024
and 16 more in the library