This research proposes to evaluate Transcendental Meditation (TM) as a complementary integrative practice in the treatment of Anxiety Disorders. Based on WHO data and the Brazilian context, the study highlights the high prevalence of anxiety and the need for therapeutic alternatives beyond the biomedical model. The research, conducted with adults diagnosed in the state of São Paulo, used online...
Objectives: Chronic musculoskeletal pain (CMP) is the leading cause of years lived with disability worldwide and the costliest health condition in the United States. Mindfulness is an effective treatment for CMP, but traditional mindfulness-based interventions (MBIs) are inaccessible for many CMP patients for both format and content reasons. An MBI that leverages music may be a more accessible...
Pharmacological ResearchNovember 22, 2025Zhuo-Ning Zhang, Xin-Yu Hao, Chen Cai et al.5 citations
This randomized, double-blind, parallel-group trial evaluated the efficacy of a single intravenous dose of esketamine (0.3mg/kg) administered at anesthesia induction in reducing postoperative depression and anxiety among patients undergoing cardiac valve surgery. A total of 142 patients from three centers were randomly assigned to receive esketamine or saline. The primary outcomes were the...
Scientia PsychiatricaNovember 19, 2025Ni Wayan Saka Rahayu, Putu Risdianto Eka Putra
Introduction: The pervasive integration of digital media into pediatric life has shifted the clinical focus from screen time quantity to content quality. Emerging "metaphysical" sub-genres, such as algorithmic "Lucid Dreaming" tutorials, pose unique risks to preadolescents. This case report aims to document a novel presentation of acute sleep anxiety precipitated specifically by "Lucid...
Correction: Correction: Effectiveness and satisfaction of mindfulness-based cognitive therapy for children on anxiety, depression, and internet addiction in adolescents: Study protocol for a randomized control trial.
Background: Buspirone shows a certain efficacy in patients with generalized anxiety disorder (GAD), but its combination therapy with mindfulness-based cognitive therapy (MBCT) remains unclear. To compare buspirone + MBCT versus buspirone alone for GAD in a retrospective cohort. Methods: According to the treatment regimens, patients were assigned to the experimental group (n = 50) to receive 120...
Research SquareNovember 11, 2025Xuming Zhu, Xiaoyong Wei, Qianyu Guo et al.
preprint
Abstract Background: The incidence of preoperative anxiety in children is significantly higher than in adults. Esketamine, the dextrorotatory enantiomer of ketamine, has been shown to alleviate preoperative anxiety in children effectively. Previous studies have established the effective dose (ED 50 ) of esketamine for reducing anxiety in pediatric patients. However, the 95% effective dose (ED...
BMC NursingNovember 6, 2025Sayedeh Farkhondeh Safavi, Hakimeh Vahedparast, Batool Amiri et al.
BACKGROUND: Informal caregivers play a crucial supportive role throughout the course of illnesses, particularly in patients with cancer. Following a cancer diagnosis, informal caregivers often experience substantial psychological, physical, and social stress, which may lead to conditions such as anxiety and sleep disturbances. Therefore, implementing interventions aimed at reducing anxiety and...
Social anxiety has become a prevalent psychological distress globally, severely impairing individuals’ social functioning and mental health. Existing intervention measures have limitations such as high dependence on professional guidance and poor long-term sustainability, making it urgent to explore innovative and accessible intervention approaches. This study aims to examine the mitigative...
The Apollo wearable device (wrist or ankle) is an investigational device which provides touch therapy with silent vibrations that may help individuals reduce the symptoms of stress such as difficulty breathing, sleeping or focusing on tasks. Positive feedback from a mental health treatment program that uses ketamine-assisted therapy as a treatment adjunct inspired researchers to assess the...