Clinical trials investigating psychedelic compounds for depression and anxiety-related disorders are yielding promising preliminary results. Psychedelics produce profound alterations in brain function—such as suppression of the default mode network and thalamocortical dysregulation—leading to intense subjective experiences including ego dissolution and mystical-type states. While often...
Sacred architecture has historically served to communicate religious teachings and elicit spiritual experiences. Although theologians and architects have offered explanations for this phenomenon, empirical evidence supporting these claims remains scarce. Scientific research on religious responses has usually overlooked architecture's role in shaping them. This study utilizes mobile...
Mind‑body practices, such as meditation and yoga, involve paying attention to breathing sensations. During these practices, individuals report "interoceptive lapses," moments when attention drifts away from internal bodily sensations. While lapses in attention to the external world have been widely studied, little is known about the physiological and neural mechanisms of interoceptive lapses....
Journal of Psychiatric ResearchJune 23, 2026Júlio César Claudino Dos Santos, Sofia Januário Bolan, Guilherme Lodetti da Silva et al.
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by persistent deficits in social communication and interaction, restricted and repetitive patterns of behavior, and sensory processing alterations, frequently accompanied by anxiety, emotional dysregulation, and other psychiatric comorbidities. Despite advances in behavioral and pharmacological...
JMIR NursingJune 22, 2026Gloria Guerrero-Pertiñez, Vera Carbonell, Jonathan Joseph Dawood-Histrova et al.
Background: Health care professionals are exposed to high levels of occupational stress, emotional exhaustion, and anxiety-depressive symptoms. Digital interventions using mindfulness- and acceptance-based approaches have shown promising results in improving psychological well-being in this population. The MINDxYOU program is a self-guided digital intervention designed to reduce perceived...
Abstract Objectives: This study examined the effect of a mindfulness-based intervention based on the Wheel of Awareness practice on psychological distress and access to internal states, within the framework of the Seeking Proxies for Internal States (SPIS) model of obsessive-compulsive disorder (OCD). The intervention aimed to enhance mindfulness skills, improve access to internal experiences,...
HealthcareJune 21, 2026Ebru Durusoy, Abdülhakim İbrahim Ulusoy, Özge Önürmen Zeyrek et al.
Background: Fibromyalgia is a chronic condition characterised by widespread pain, fatigue, sleep disturbances, and psychological symptoms. Mindfulness-based approaches are increasingly used as complementary interventions for symptom management. This study aimed to investigate the effectiveness of mindfulness-based yoga (MBY) delivered via telerehabilitation in individuals with fibromyalgia....
Out-of-body experiences (OBEs) during sleep involve a transient disruption of bodily self-consciousness, in which the self or center of awareness is experienced as displaced from the physical body. Although OBEs have been reported in neurological, psychiatric, and dissociative contexts, they also occur in non-clinical populations, raising the question of whether their altered-self phenomenology...
Objective: To evaluate the effect of mindfulness training in addition to essential psychological counseling on the clinical pregnancy rate in women undergoing frozen embryo transfer (FET), and to explore the potential mediating role of neuropsychological improvements. Methods and analysis: This study will be conducted as a single-center, parallel-group, open-label, exploratory randomized...
An essay on sleep as the separation of mind and body, written by someone who does not get much of it. It moves from a joke in a cartoon to the genetics of familial natural short sleep and the contemplative traditions that train the mind to stay awake while the body rests, and it is careful to say which of those the author is standing in — neither. The sleep genetics describes a rare inherited...