Substance use disorders (SUD) involving ketamine, cocaine, and alcohol present significant clinical challenges, often characterized by high relapse rates and limited pharmacological options. This case report details a 30-year-old male with a five-year history of severe polysubstance dependence, including daily intranasal ketamine use (2–3 g/day), cocaine, and alcohol, comorbid with recurrent...
This study undertakes a comprehensive philosophical and literary investigation of Ahalyā, the remarkable long poem by the eminent Odia poet Dr. Phani Mohanty, translated into English by Sonali Sahu. Rather than treating Ahalyā merely as a mythological character from the Ramayana, the poem reconstructs her into a universal symbol of human suffering, feminine consciousness, existential...
This chapter explores the role of mindfulness in enhancing resilience, attention, and well-being among law students, drawing on the latest findings in cognitive neuroscience. Legal education places intense cognitive and emotional demands on students, often resulting in stress, anxiety, and cognitive decline. The authors present empirical evidence demonstrating how mindfulness...
This chapter offers research-based methods for integrating Mindful Self-Compassion (MSC) into law school curricula and professional development. Meta-analyses and other empirical studies demonstrate that MSC enhances resilience, reduces depression and anxiety, mitigates burnout, fosters interpersonal connection, and supports peak performance. MSC complements widely practiced mindfulness...
Abstract Psilocybin is a serotonergic psychedelic drug with emerging therapeutic applications, yet its actions under glutamatergic dysfunction, and relevance to schizophrenia and associated psychiatric disorders, remain unclear. We examined the acute and long-lasting effects of psilocybin (1 mg/kg, intraperitoneal) on behavioral and neural outcomes in the metabotropic glutamate receptor 5...
FigshareJuly 17, 2026Wenjie Liu, Tian Yuan, Li Wang et al.
preprint
The COVID-19 pandemic has profoundly restructured daily life, significantly impacting mental health. This negative event has been reported to alter subjective experience of time, such as the blending of days, reflecting distortions in long-term time perception over relatively coarse scales. However, the influence of the COVID-19 pandemic on short-term time perception over fine scales has...
Objective: The objective of this narrative review is to understand what forms of spirituality screening and spiritual support are available to individuals with serious or life-threating illness involved in psychedelic-assisted therapies. Introduction: In addition to physical pain related to disease and treatment processes, people encountering serious illness frequently experience psychological...
Background: For millennia, mantra-based meditation practices, including Transcendental Meditation (TM), have been central to various contemplative traditions. In recent decades, these techniques have become a focus of rigorous scientific investigation, primarily within the field of stress medicine. Aim: This paper aims to synthesise the current evidence on the physiological and psychological...
The modern quest for psychological well-being increasingly draws from both scientific and spiritual traditions. This proposed chapter explores how mindfulness, rooted in Eastern esotericism, and cognitive-behavioral approaches, grounded in Western psychology, converge to foster resilience and emotional balance among elderly populations. With age-related transitions often accompanied by...
Categorical nosological systems frequently fall short when confronted with patients whose presentations cross established diagnostic boundaries. We report M.S., a 44-year-old Brazilian man involuntarily admitted to a psychiatric inpatient unit who presented with systematized persecutory ideation of mechanistic–technological content (chip implantation, satellite-based surveillance), structural...