Annals of the New York Academy of Sciences
August 1, 2006
Raquel Faria, Ana Magalhães, Pedro Monteiro et al.
29 citations
Abstract: Long‐term behavioral consequences of the neurotoxicity produced by 3,4‐methylenedioxymethamphetamine (MDMA) in the adolescent rat are still mostly unknown. Here, adolescent male rats (postnatal day 45 PND [45]) were exposed to 10 mg/kg of MDMA, intraperitoneally, every 2 h for 6 h. Controls were given 0.9% saline in the same protocol. Ten days after exposure, the behavioral effects of...
Psychopharmacology
July 7, 2006
Roland R. Griffiths, William A. Richards, U. Mccann et al.
1,684 citations
RationaleAlthough psilocybin has been used for centuries for religious purposes, little is known scientifically about its acute and persisting effects.ObjectivesThis double-blind study evaluated the acute and longer-term psychological effects of a high dose of psilocybin relative to a comparison compound administered under comfortable, supportive conditions.Materials and methodsThe participants...
Brazilian Journal of Medical and Biological Research
April 1, 2006
Antônio Waldo Zuardi, José A. Crippa, Jaime E. C. Hallak et al.
411 citations
A high dose of delta9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of delta9-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspect that CBD could have anxiolytic...
Journal of Psychopharmacology
March 30, 2006
Kirstie Soar, John Turner, A. C. Parrott
65 citations
Recreational ecstasy (3,4-methylenedioxymethamphetamine; MDMA) use has been increasingly associated with a number of psychiatric symptoms and psychological problems. However, previous studies assessing possible psychopathological effects have not identified whether users consider their ecstasy use ‘problematic’ or not. In addition, research has generally failed to address the potential role of...
Addiction
March 24, 2006
Chelsea A. Baylen, Harold Rosenberg
214 citations
ABSTRACT Aim Although several relatively recent reviews have summarized the neuropsychiatric effects associated with chronic ecstasy use, there is no published comprehensive review of studies on the acute subjective effects (ASEs) of MDMA/ecstasy. Design The present study reviewed the prevalence, intensity and duration of ASEs collected from 24 studies that provided frequency data on the...
Transcultural Psychiatry
March 1, 2005
Devon E Hinton, Vuth Pich, Dara Chhean et al.
Among a psychiatric population of Cambodian refugees (N = 100), 42% had current--i.e. at least once in the last year--sleep paralysis (SP). Of those experiencing SP, 91% (38/42) had visual hallucinations of an approaching being, and 100% (42/42) had panic attacks. Among patients with post-traumatic stress disorder (PTSD; n = 45), 67% (30/45) had SP, whereas among those without PTSD, only 22.4%...
Depression and Anxiety
2005
Devon E Hinton, Vuth Pich, Dara Chhean et al.
Among Cambodian refugees attending a psychiatric clinic (n=100), 49% (49/100) had at least one episode of sleep paralysis (SP) in the previous 12 months. The annual and monthly SP prevalences were much higher in posttraumatic stress disorder (PTSD) than in non-PTSD patients. Among the PTSD patients, 65% (30/46) had monthly episodes of SP versus 14.85% (8/54) among non-PTSD patients (chi2[2,...
British journal of sports medicine
October 1, 2004
A Dietrich, W F McDaniel
Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes. This article provides an overview of this emerging field.
Assessment
September 1, 2004
Ruth A. Baer, Gregory T. Smith, Kristin B. Allen
2,283 citations
A self-report inventory for the assessment of mindfulness skills was developed, and its psychometric characteristics and relationships with other constructs were examined. Participants included three samples of undergraduate students and a sample of outpatients with borderline personality disorder Based on discussions of mindfulness in the current literature, four mindfulness skills were...
Drugs Education Prevention and Policy
June 1, 2004
Sarah Riley, Emma Hayward
52 citations
A survey of drug use in the past year was completed by 124 clubbers (50% male, 50% female, age range 14–44, mean 24 years). Participants were self selecting and recruited in clubs and pre-club bars. Prevalence rates for alcohol, cannabis, and ecstasy were over 80%; 63% reported cocaine and 53% amphetamine use, 15%–43% used ketamine, psilocybin, LSD and nitrites. A pattern of polydrug and...