Brazilian Journal of Medical and Biological Research
September 2, 2025
A. Walsh-Monteiro, S. Morato, F.a.r. Uribe et al.
This systematic review investigates the effects of the ayahuasca beverage (Aya) in various animal models. Using the PRISMA protocol and adhering to the Cochrane Handbook for Systematic Reviews, a comprehensive selection of 2,359 documents was identified from the Web of Science, Medline, and Scopus databases between 2012 and 2022. Following the inclusion and exclusion criteria, 14 articles were...
Brazilian Journal of Medical and Biological Research
June 20, 2020
A.p.s. Campagnoli, L.a.s. Pereira, José Lino Oliveira Bueno
11 citations
Ayahuasca is described as a hallucinogenic substance whose property is to alter the subjective experience of time and impair the perception of the passage of time during stimuli of more than two to three seconds. The dose-dependent effects of two concentrations of ayahuasca in the ritualistic context were investigated employing temporal reproduction tasks in participants experienced in...
Brazilian Journal of Medical and Biological Research
2017
Nelson Francisco Correa-Netto, M.y. Masukawa, F. Nishide et al.
20 citations
Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups. However, little is known of the effects of ayahuasca during ontogenic development, particularly with regard to the functional characteristics of the central nervous system. Animal models are useful for studying the ontogenic...
Brazilian Journal of Medical and Biological Research
2017
Nelson Francisco Correa-Netto, L.s. Coelho, G Galfano et al.
10 citations
The Quechua term ayahuasca refers to a beverage obtained from decoctions of the liana Banisteriopsis caapi with leaves of Psychotria viridis. The ritualistic use of ayahuasca is becoming a global phenomenon, with some individuals using this beverage throughout life, including in old age. Cognitive impairment is a common manifestation during aging. There are conflicting reports on the ability of...
Brazilian Journal of Medical and Biological Research
September 4, 2013
V. Ferraz-De-Paula, D. Stankevicius, A. Ribeiro et al.
10 citations
Anxiolytic and anxiogenic-like behavioral outcomes have been reported for methylenedioxymethamphetamine (MDMA or ecstasy) in rodents. In the present experiment, we attempted to identify behavioral, hormonal and neurochemical outcomes of MDMA treatment to clarify its effects on anxiety-related responses in 2-month-old Balb/c male mice (25-35 g; N = 7-10 mice/group). The behavioral tests used...
Brazilian Journal of Medical and Biological Research
April 1, 2006
Antônio Waldo Zuardi, José A. Crippa, Jaime E. C. Hallak et al.
411 citations
A high dose of delta9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of delta9-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspect that CBD could have anxiolytic...